87 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
    1
    1. scibot 16 Nov 2024
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      DOI: 10.1016/j.cell.2024.10.012

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    sciencedirect.com/science/article/pii/S0092867424011887
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    Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
    1
    1. scibot 11 Nov 2024
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    sciencedirect.com/science/article/pii/S1535610824003982
  4. Sep 2024
  5. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1113/JP286460

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP286460
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    Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway
    1
    1. scibot 12 Sep 2024
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    sciencedirect.com/science/article/pii/S0003986124002753
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1038/s41467-024-51030-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11344041/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
    1
    1. scibot 26 Aug 2024
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      DOI: 10.1101/2024.08.09.607311

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    ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
  10. www.cell.com www.cell.com
    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.cmet.2024.07.014

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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00285-7
  11. Jul 2024
  12. www.sciencedirect.com www.sciencedirect.com
    CircEZH2 Promotes Gallbladder Cancer Progression and Lipid Metabolism Reprogramming through the miR-556-5p/SCD1 Axis
    1
    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S2589004224016535
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
    1
    1. scibot 27 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960274/
  15. Feb 2024
  16. www.sciencedirect.com www.sciencedirect.com
    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
    1
    1. scibot 16 Feb 2024
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    sciencedirect.com/science/article/pii/S1534580724000443
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1126/sciadv.adk1835

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866549/
  18. www.sciencedirect.com www.sciencedirect.com
    Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1016/j.isci.2024.109075

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    sciencedirect.com/science/article/pii/S2589004224002967
  19. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
    1
    1. scibot 13 Feb 2024
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    mdpi.com/1467-3045/45/12/620
  20. www.sciencedirect.com www.sciencedirect.com
    Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.cmet.2024.01.008

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    sciencedirect.com/science/article/pii/S1550413124000081
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
    1
    1. scibot 03 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0358

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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
  22. Jan 2024
  23. www.sciencedirect.com www.sciencedirect.com
    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.015

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    sciencedirect.com/science/article/pii/S1550413123004655
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Stress-induced β cell early senescence confers protection against type 1 diabetes
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.cmet.2023.10.014

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    sciencedirect.com/science/article/pii/S1550413123003832
  26. Oct 2023
  27. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.cmet.2023.09.012

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    sciencedirect.com/science/article/pii/S1550413123003686
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    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.cmet.2023.09.004

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    sciencedirect.com/science/article/pii/S1550413123003364
  29. Sep 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training
    1
    1. scibot 07 Sep 2023
      RRID:AB_2715528

      DOI: 10.1016/j.redox.2023.102873

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    sciencedirect.com/science/article/pii/S2213231723002744
  31. Aug 2023
  32. www.sciencedirect.com www.sciencedirect.com
    4-Octyl itaconate restricts STING activation by blocking its palmitoylation
    1
    1. scibot 25 Aug 2023
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      DOI: 10.1016/j.celrep.2023.113040

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    sciencedirect.com/science/article/pii/S2211124723010513
  33. Jul 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
    1
    1. scibot 22 Jul 2023
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      DOI: 10.4103/1673-5374.373715

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    ncbi.nlm.nih.gov/pmc/articles/PMC10358659/
  35. 52.53.155.43 52.53.155.43
    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
    1
    1. scibot 18 Jul 2023
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      DOI: 10.1101/2023.05.29.542776

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    52.53.155.43/295724fe7577204c05a5e312c5e68d353e69e1f1/2023.05.29.542776v1.full-html.html
  36. www.sciencedirect.com www.sciencedirect.com
    Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.isci.2023.107199

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    sciencedirect.com/science/article/pii/S2589004223012762
  37. www.sciencedirect.com www.sciencedirect.com
    Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons
    1
    1. scibot 12 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112746

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    sciencedirect.com/science/article/pii/S221112472300757X
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts
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    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.isci.2023.107113

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    sciencedirect.com/science/article/pii/S2589004223011902
  40. www.mdpi.com www.mdpi.com
    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
    1
    1. scibot 23 Jun 2023
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      DOI: 10.3390/antiox12061303

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    mdpi.com/2076-3921/12/6/1303
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
    1
    1. scibot 17 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-3848

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    ncbi.nlm.nih.gov/pmc/articles/PMC10267679/
  42. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Investigating the effects of 7-ketocholesterol on retinal pigment epithelium bioenergetics
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1096/fj.202300101R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300101R
  43. May 2023
  44. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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      DOI: 10.1016/j.celrep.2023.112536

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    sciencedirect.com/science/article/pii/S2211124723005478
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    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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      DOI: 10.1016/j.molcel.2023.04.023

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    sciencedirect.com/science/article/pii/S1097276523003179
  46. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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    mdpi.com/2076-3921/10/9/1387/htm
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of NADPH oxidase 4 reduces mitochondrial... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154488/
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  49. Apr 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing
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      DOI: 10.1016/j.scr.2023.103090

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    sciencedirect.com/science/article/pii/S1873506123000764
  51. Mar 2023
  52. 52.53.155.43 52.53.155.43
    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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    52.53.155.43/33a195c50d3c1e499f909c4b656134732d9eadf9/Inhibiting_tau_protein_improves_the_recovery_of.42-html.html
  53. Feb 2023
  54. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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    sciencedirect.com/science/article/pii/S1550413123000104
  55. Dec 2022
  56. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
    1
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      DOI: 10.3390/nu14245265

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    mdpi.com/2072-6643/14/24/5265
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    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
    1
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      DOI: 10.3390/cimb44120402

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  58. Nov 2022
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  60. Oct 2022
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  62. Aug 2022
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    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
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  64. Jul 2022
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    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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  67. May 2022
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  69. Mar 2022
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    The Protective Effects of Trans-Cinnamaldehyde against D-Galactose and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
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    Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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  73. Feb 2022
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    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
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  75. Jan 2022
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    The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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  80. Sep 2021
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    Structural basis and regulation of the reductive stress response
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  82. Aug 2021
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    A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
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  85. Jul 2021
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    A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
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  87. Jun 2021
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    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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  89. May 2021
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    Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection
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    Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential
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    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
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  94. Apr 2021
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  97. Feb 2021
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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  99. Nov 2020
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    Effect of Treadmill Exercise and Trans-Cinnamaldehyde against d-Galactose- and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
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  101. Sep 2020
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    Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection
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    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
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    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
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    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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    Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity
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    Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury
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    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      rabbit anti-NFE2L2/Nrf2

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  111. Jan 2020
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    HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice
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    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
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    Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1
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    Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
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    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
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      DOI: 10.1016/j.cell.2019.06.005

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      DOI: 10.1016/j.ccell.2018.12.009

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1186/s12974-019-1495-3

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  119. www.sciencedirect.com www.sciencedirect.com
    Mitohormesis Primes Tumor Invasion and Metastasis
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      DOI: 10.1016/j.celrep.2019.04.095

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  120. Nov 2018
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal activity induces glutathione metabolism gene expression in astrocytes
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    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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  124. Nov 2017
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    Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
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