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Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

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1. scibot 27 Sep 2025
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.immuni.2025.09.003
  
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sciencedirect.com/science/article/pii/S1074761325004145
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

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1. scibot 06 Aug 2025
  
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  RRID:AB_2716208
  
  DOI: 10.1158/2159-8290.CD-24-1425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

1
1. scibot 03 Jun 2025
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
Jul 2024
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

1
1. scibot 25 Jul 2024
  
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  AB_2716208
  
  DOI: 10.1016/j.celrep.2024.114506
  
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sciencedirect.com/science/article/pii/S2211124724008350
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

1
1. scibot 21 May 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
Mar 2024
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Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment

2
1. scibot 15 Mar 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.cmet.2024.02.009
  
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2. scibot 15 Mar 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.cmet.2024.02.009
  
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sciencedirect.com/science/article/pii/S155041312400055X
Jan 2024
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Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

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1. scibot 12 Jan 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.ccell.2023.12.013
  
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sciencedirect.com/science/article/pii/S1535610823004415
aacrjournals.org aacrjournals.org

Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade

1
1. scibot 11 Jan 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1158/2159-8290.CD-22-1301
  
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aacrjournals.org/cancerdiscovery/article/13/12/2566/731588/Formate-Supplementation-Enhances-Antitumor-CD8-T
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
1. scibot 04 Jan 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.devcel.2023.07.025
  
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2. scibot 04 Jan 2024
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Dec 2023
52.53.155.43 52.53.155.43

cd-22-1301-html.html

1
1. scibot 01 Dec 2023
  
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  RRID:AB_2716208
  
  DOI: 10.1158/2159-8290.cd-22-1301
  
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52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
Aug 2023
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CTLA-4 blockade induces CD4+ T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma

1
1. scibot 12 Aug 2023
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.immuni.2023.07.015
  
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sciencedirect.com/science/article/abs/pii/S107476132300328X
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Interventional hydrogel microsphere vaccine as an immune amplifier for activated antitumour immunity after ablation therapy

1
1. scibot 14 Jul 2023
  
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  RRID:AB_2716208
  
  DOI: 10.1038/s41467-023-39759-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10336067/
Apr 2023
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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

1
1. scibot 29 Apr 2023
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.celrep.2023.112436
  
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sciencedirect.com/science/article/pii/S2211124723004473
Dec 2022
aacrjournals.org aacrjournals.org

Stress-mediated attenuation of translation undermines T-cell activity in cancer

1
1. scibot 03 Dec 2022
  
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  RRID:AB_2716208
  
  DOI: 10.1158/0008-5472.CAN-22-1744
  
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aacrjournals.org/cancerres/article/82/23/4386/710692/Stress-Mediated-Attenuation-of-Translation
52.53.155.43 52.53.155.43

can-22-1744-html.html

1
1. scibot 01 Dec 2022
  
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  AB_2716208
  
  DOI: 10.1158/0008-5472.CAN-22-1744
  
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52.53.155.43/ad84fbadafd7207ef01b11f7e83790e81459d855/can-22-1744-html.html
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion

1
1. scibot 27 Jul 2022
  
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  AB_2716208
  
  DOI: 10.3389/fimmu.2022.878320
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9301332/
www.cell.com www.cell.com

Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

1
1. scibot 13 Jul 2022
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.cmet.2022.06.008
  
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cell.com/cell-metabolism/fulltext/S1550-4131(22)00228-5
Jun 2022
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Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models

1
1. scibot 09 Jun 2022
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.xpro.2022.101444
  
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sciencedirect.com/science/article/pii/S2666166722003240
Apr 2022
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Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches

1
1. scibot 07 Apr 2022
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.immuni.2022.03.006
  
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sciencedirect.com/science/article/pii/S1074761322001297
Feb 2022
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

1
1. scibot 04 Feb 2022
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.ccell.2022.01.002
  
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sciencedirect.com/science/article/pii/S1535610822000046
Jun 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

1
1. scibot 08 Jun 2021
  
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  RRID:AB_2716208
  
  DOI: 10.1016/j.immuni.2021.05.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9273026/