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71 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

1
1. scibot 04 Nov 2025
  
  in Public
  
  anti-CD40 (2C10R4)
  
  DOI: 10.3389/fimmu.2025.1664463
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @giovanni.decastro
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12549273/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combined islet and kidney xenotransplantation for diabetic nephropathy: an update in ongoing research for a clinically relevant application of porcine islet transplantation

1
1. scibot 25 Mar 2025
  
  in Public
  
  anti-CD40 mAb (Nonhuman Primate Reagent Resource
  
  DOI: 10.3389/fimmu.2024.1351717
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @giovanni.decastro
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10927755/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights

1
1. scibot 19 Mar 2025
  
  in Public
  
  mouse/rhesus chimeric IgG4 clone 2C10R4
  
  DOI: 10.3390/biomedicines12061336
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @giovanni.decastro
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11201800/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeted mapping and utilization of the perihepatic surface for therapeutic beta cell replacement and retrieval in diabetic non-human primates

1
1. scibot 19 Mar 2025
  
  in Public
  
  anti-CD40 mAb 2C10R4
  
  DOI: 10.3389/frtra.2024.1352777
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @giovanni.decastro
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11235263/
Aug 2024
www.jtcvs.org www.jtcvs.org

The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors

1
1. scibot 02 Aug 2024
  
  in Public
  
  anti-CD40 (clone 2C10R4; NHP Reagent Resource
  
  DOI: 10.1016/j.jtcvs.2021.07.051
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
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  RRID:AB_2716325 RRIDCUR:Missing
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jtcvs.org/article/S0022-5223(21)01261-7/fulltext
May 2024
www.jtcvs.org www.jtcvs.org

The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors

1
1. scibot 15 May 2024
  
  in Public
  
  anti-CD40 (clone 2C10R4; NHP Reagent Resource
  
  DOI: 10.1016/j.jtcvs.2021.07.051
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 DOI:10.1016/j.jtcvs.2021.07.051
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DOI:10.1016/j.jtcvs.2021.07.051

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jtcvs.org/article/S0022-5223(21)01261-7/fulltext
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Initial evidence that blockade of the CD40/CD154 costimulation pathway alone is sufficient as maintenance therapy in xenotransplantation

1
1. scibot 03 Nov 2023
  
  in Public
  
  Anti-CD40 monoclonal antibody (mAb) (2C10R4
  
  DOI: 10.1111/xen.12721
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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onlinelibrary.wiley.com/doi/10.1111/xen.12721
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Erratum: Increase in Anti-Gal IgM Level is Associated With Early Graft Failure in Intraportal Porcine Islet Xenotransplantation

1
1. scibot 03 Nov 2023
  
  in Public
  
  anti-CD40
  
  DOI: 10.3343/alm.2016.36.5.504
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4940499/
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T and B lymphocyte dynamics after genetically-modified pig-to-baboon kidney xenotransplantation with an anti-CD40mAb-based immunosuppressive regimen

1
1. scibot 25 Oct 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4
  
  DOI: 10.1016/j.trim.2022.101545
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC9395207/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Bullous pemphigoid-like skin blistering disease in a rhesus macaque (Macaca mulatta)

1
1. scibot 25 Oct 2023
  
  in Public
  
  2C10R4
  
  DOI: 10.1111/jmp.12225
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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onlinelibrary.wiley.com/doi/10.1111/jmp.12225
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

1
1. scibot 25 Oct 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4)
  
  DOI: 10.1038/s41598-020-66311-3
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7300119/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stable expression of the human thrombomodulin transgene in pig endothelial cells is associated with a reduction in the inflammatory response

1
1. scibot 25 Oct 2023
  
  in Public
  
  Anti-CD40 2C10R4
  
  DOI: 10.1016/j.cyto.2021.155580
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8511266/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

One-Year Heterotopic Cardiac Xenograft Survival In A Pig To Baboon Model

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti CD40 antibody (clone 2C10R4
  
  DOI: 10.1111/ajt.12562
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC4184155/
www.sciencedirect.com www.sciencedirect.com

Comparative efficacy of anti-CD40 antibody–mediated costimulation blockade on long-term survival of full-thickness porcine corneal grafts in nonhuman primates

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 Ab (2C10R4
  
  DOI: 10.1111/ajt.14913
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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sciencedirect.com/science/article/pii/S1600613522097052
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 2C10R4
  
  DOI: 10.1111/xen.12715
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC9157534/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SERUM AMYLOID A AS AN INDICATOR OF IMPENDING XENOGRAFT FAILURE: EXPERIMENTAL STUDIES

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40mAb (2C10R4
  
  DOI: 10.1016/j.ijsu.2018.11.027
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC6310230/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 mAb 2C10R4
  
  DOI: 10.1038/s41467-019-11338-y
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC6677762/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Kidney transplantation from triple‐knockout pigs expressing multiple human proteins in cynomolgus macaques

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti‐CD40 (2C10R4
  
  DOI: 10.1111/ajt.16780
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC9291868/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Predictive biomarkers for graft rejection in pig-to-non-human primate corneal xenotransplantation

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 Ab (2C10R4
  
  DOI: 10.1111/xen.12515
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC6717035/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Failure of transplantation tolerance induction by autologous regulatory T cells in the pig-to-non-human primate islet xenotransplantation model

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 mAb (20 mg/kg, i.v. 2C10 R4 clone
  
  DOI: 10.1111/xen.12246
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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onlinelibrary.wiley.com/doi/10.1111/xen.12246
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long-term safety outcome of systemic immunosuppression in pig-to-nonhuman primate corneal xenotransplantation

1
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 Abs (2C10R4
  
  DOI: 10.1111/xen.12442
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC6166667/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis

2
1. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 Ab 2C10R4
  
  DOI: 10.1172/JCI76357
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
2. scibot 25 Oct 2023
  
  in Public
  
  anti-CD40 Ab 2C10R4
  
  DOI: 10.1172/JCI76357
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC4382240/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Addition of Anti-CD40 Monoclonal Antibody to Nonmyeloablative Conditioning with Belatacept Abrogated Allograft Tolerance Despite Induction of Mixed Chimerism

1
1. scibot 25 Oct 2023
  
  in Public
  
  RRID:AB_2716325
  
  DOI: 10.1097/TP.0000000000002417
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC6309923/
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

2
1. scibot 16 Jun 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4
  
  DOI: 10.1111/xen.12293
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRIDCUR:Missing RRID:AB_2716325
2. scibot 16 Jun 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4, a chimeric rhesus IgG4) was provided by the NIH NHP Reagent Resource
  
  DOI: 10.1111/xen.12293
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRIDCUR:Missing RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC5397334/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FURTHER EVIDENCE FOR SUSTAINED SYSTEMIC INFLAMMATION IN XENOGRAFT RECIPIENTS (SIXR)

1
1. scibot 16 Jun 2023
  
  in Public
  
  2C10R4
  
  DOI: 10.1111/xen.12182
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRIDCUR:Missing RRID:AB_2716325
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RRIDCUR:Missing

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ncbi.nlm.nih.gov/pmc/articles/PMC4575631/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Myroides Infection in a Baboon After Prolonged Pig Kidney Graft Survival

1
1. scibot 16 Jun 2023
  
  in Public
  
  anti-CD40mAb from the NHP Reagent Resource
  
  DOI: 10.1097/TXD.0000000000000523
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRIDCUR:Missing RRID:AB_2716325
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ncbi.nlm.nih.gov/pmc/articles/PMC4486305/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

“You cannot stay in the laboratory forever”*: Taking pig kidney xenotransplantation from the laboratory to the clinic

1
1. scibot 15 Jun 2023
  
  in Public
  
  Anti-CD40 monoclonal antibody (mAb) (2C10R4, a chimeric rhesus IgG4
  
  DOI: 10.1016/j.ebiom.2021.103562
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC8441149/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure

1
1. scibot 14 Jun 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4, a chimeric rhesus IgG4
  
  DOI: 10.3389/fimmu.2021.788949
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC8692283/
www.nature.com www.nature.com

Consistent success in life-supporting porcine cardiac xenotransplantation

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40
  
  DOI: 10.1038/s41586-018-0765-z
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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nature.com/articles/s41586-018-0765-z
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model

1
1. scibot 14 Jun 2023
  
  in Public
  
  2C10R4
  
  DOI: 10.1097/TXD.0000000000000761
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC5811273/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Delayed revascularization of islet after transplantation by IL-6 blockade in pig to nonhuman primate islet xenotransplantation model

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 mAb (2C10R4
  
  DOI: 10.1111/xen.12374
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC5903442/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pre-clinical results in pig-to-nonhuman primate islet xenotransplantation using anti-CD40 antibody (2C10R4)-based immunosuppression

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 mAb (2C10R4
  
  DOI: 10.1111/xen.12356
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRID:AB_2716325 RRIDCUR:Missing
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5809197/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AN INVESTIGATION OF EXTRACELLULAR HISTONES IN PIG-TO-BABOON ORGAN XENOTRANSPLANTATION

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40mAb (2C10R4
  
  DOI: 10.1097/TP.0000000000001676
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5856196/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model

1
1. scibot 14 Jun 2023
  
  in Public
  
  2C10R4
  
  DOI: 10.1097/TP.0000000000001836
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5568940/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Co-Stimulation Blockade

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 monoclonal antibody
  
  DOI: 10.1111/ajt.14341
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5519420/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Anti-CD40 antibody mediated-costimulation blockade promotes long-term survival of deep-lamellar porcine corneal grafts in non-human primates

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 (2C10R4
  
  DOI: 10.1111/xen.12298
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5464973/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immunosuppression with CD40 Costimulatory Blockade plus Rapamycin for Simultaneous Islet and Kidney Transplantation in Nonhuman Primates

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 mAb
  
  DOI: 10.1111/ajt.13999
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5298941/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TRANSPLANTATION OF HEPATOCYTES FROM GENETICALLY-ENGINEERED PIGS IN BABOONS

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40mAb
  
  DOI: 10.1111/xen.12289
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5397320/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thyroid hormone: relevance to xenotransplantation

1
1. scibot 14 Jun 2023
  
  in Public
  
  Anti-CD40 (2C10R4
  
  DOI: 10.1111/xen.12243
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4988877/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

1
1. scibot 14 Jun 2023
  
  in Public
  
  αCD40 (clone 2C10R4
  
  DOI: 10.1038/ncomms11138
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4822024/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IN VITRO TESTING OF AN ANTI-CD40 MONOCLONAL ANTIBODY, CLONE 2C10, IN PRIMATES AND PIGS

1
1. scibot 14 Jun 2023
  
  in Public
  
  Anti-CD40mAb (clone 2C10R4
  
  DOI: 10.1016/j.trim.2015.09.007
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4648655/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIG KIDNEY GRAFT SURVIVAL IN A BABOON FOR 136 DAYS: LONGEST LIFE-SUPPORTING ORGAN GRAFT SURVIVAL TO DATE

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40mAb
  
  DOI: 10.1111/xen.12174
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4519393/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIG-TO-BABOON HETEROTOPIC HEART TRANSPLANTATION – EXPLORATORY PRELIMINARY EXPERIENCE WITH PIGS TRANSGENIC FOR HUMAN THROMBOMODULIN AND COMPARISON OF THREE COSTIMULATION BLOCKADE-BASED REGIMENS

1
1. scibot 14 Jun 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4
  
  DOI: 10.1111/xen.12167
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4464944/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

INITIAL IN VIVO EXPERIENCE OF PIG ARTERY PATCH TRANSPLANTATION IN BABOONS USING MUTANT MHC (CIITA-DN) PIGS

1
1. scibot 14 Jun 2023
  
  in Public
  
  Anti-CD40mAb
  
  DOI: 10.1016/j.trim.2015.02.003
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4368496/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long-term safety from transmission of porcine endogenous retrovirus after pig-to-nonhuman primate corneal transplantation

1
1. scibot 14 Jun 2023
  
  in Public
  
  anti-CD40 antibodies (2C10R4
  
  DOI: 10.1111/xen.12314
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRID:AB_2716325 RRIDCUR:Missing
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5546926/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CD4+/CD8+ T cell ratio correlates with the graft fate in pig-to-nonhuman primate islet xenotransplantation

1
1. scibot 07 Jun 2023
  
  in Public
  
  anti-CD40 mAb (2C10R4; National Institutes of Health NHP Reagent Resource
  
  DOI: 10.1111/xen.12562
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC7162713/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients

1
1. scibot 07 Jun 2023
  
  in Public
  
  anti-CD40 mAb 20 mg/kg IV (2C10R4; NIH Nonhuman Primate Reagent Resource
  
  DOI: 10.1111/ajt.15067
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC7185755/
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection

1
1. scibot 20 Apr 2023
  
  in Public
  
  mouse-rhesus IgG4 anti-CD40, 2C10R4 (REF) (Nonhuman Primate Reagent Resource
  
  DOI: 10.1111/ajt.12526
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC3985346/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long-term safety from transmission of porcine endogenous retrovirus after pig-to-nonhuman primate corneal transplantation

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 antibodies (2C10R4, NIH Nonhuman Primate Reagent Resource)
  
  DOI: 10.1111/xen.12314
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5546926/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetically Engineered Pigs And Target Specific Immunomodulation Provide Significant Graft Survival And Hope For Clinical Cardiac Xenotransplantation

1
1. scibot 20 Apr 2023
  
  in Public
  
  Keith Reimann, PhD for providing the anti CD40 mAb
  
  DOI: 10.1016/j.jtcvs.2014.06.002
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4135017/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

INITIAL IN VIVO EXPERIENCE OF PIG ARTERY PATCH TRANSPLANTATION IN BABOONS USING MUTANT MHC (CIITA-DN) PIGS

1
1. scibot 20 Apr 2023
  
  in Public
  
  Anti-CD40mAb (NIH NHP Resource Center, Boston, MA
  
  DOI: 10.1016/j.trim.2015.02.003
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4368496/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIG-TO-BABOON HETEROTOPIC HEART TRANSPLANTATION – EXPLORATORY PRELIMINARY EXPERIENCE WITH PIGS TRANSGENIC FOR HUMAN THROMBOMODULIN AND COMPARISON OF THREE COSTIMULATION BLOCKADE-BASED REGIMENS

1
1. scibot 20 Apr 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4; NIH NHP Reagent Resource
  
  DOI: 10.1111/xen.12167
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4464944/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIG KIDNEY GRAFT SURVIVAL IN A BABOON FOR 136 DAYS: LONGEST LIFE-SUPPORTING ORGAN GRAFT SURVIVAL TO DATE

1
1. scibot 20 Apr 2023
  
  in Public
  
  We thank Dr. Keith Reimann for providing anti-CD40mAb from the NHP Reagent Resource
  
  DOI: 10.1111/xen.12174
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4519393/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IN VITRO TESTING OF AN ANTI-CD40 MONOCLONAL ANTIBODY, CLONE 2C10, IN PRIMATES AND PIGS

1
1. scibot 20 Apr 2023
  
  in Public
  
  Anti-CD40mAb (clone 2C10R4) was kindly provided by Keith Reimann through the NIH NHP Reagent Resource facility
  
  DOI: 10.1016/j.trim.2015.09.007
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4648655/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

1
1. scibot 20 Apr 2023
  
  in Public
  
  αCD40 (clone 2C10R4)15 (NHP Reagent Resource
  
  DOI: 10.1038/ncomms11138
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC4822024/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TRANSPLANTATION OF HEPATOCYTES FROM GENETICALLY-ENGINEERED PIGS IN BABOONS

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40mAb from the NHP Reagent Resource
  
  DOI: 10.1111/xen.12289
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5397320/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

THERAPEUTIC REGULATION OF SYSTEMIC INFLAMMATION IN XENOGRAFT RECIPIENTS

1
1. scibot 20 Apr 2023
  
  in Public
  
  2C10R4 was kindly provided by Keith Reimann of the NIH NHP Resource Center
  
  DOI: 10.1111/xen.12296
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5397335/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immunosuppression with CD40 Costimulatory Blockade plus Rapamycin for Simultaneous Islet and Kidney Transplantation in Nonhuman Primates

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 mAb (Nonhuman Primate Reagent Resource
  
  DOI: 10.1111/ajt.13999
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5298941/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Anti-CD40 antibody mediated-costimulation blockade promotes long-term survival of deep-lamellar porcine corneal grafts in non-human primates

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 (2C10R4, NIH Nonhuman Primate Reagent Resource
  
  DOI: 10.1111/xen.12298
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5464973/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Co-Stimulation Blockade

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 monoclonal antibody (mAb) (n = 1) (20 mg/kg on Days 0 and 5 and 10 mg/kg on Day 7 and weekly thereafter, NHP Reagent Resource
  
  DOI: 10.1111/ajt.14341
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5519420/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model

1
1. scibot 20 Apr 2023
  
  in Public
  
  5C8H1 is a mouse-human IgG1κ chimeric anti-CD154 antibody, and 2C10R4 is a mouse-rhesus IgG4κ anti-CD40 antibody.21 Both were obtained from the NIH Nonhuman Primate Reagent Resource
  
  DOI: 10.1097/TP.0000000000001836
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1547, RRID:AB_2716324)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716324
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716324 RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

RRID:AB_2716324

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5568940/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates

1
1. scibot 20 Apr 2023
  
  in Public
  
  Anti-CD40mAb (2C10) used in this study was produced and provided by the Non-human Primate Reagent Resource
  
  DOI: 10.1182/bloodadvances.2017010991
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
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  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5737135/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AN INVESTIGATION OF EXTRACELLULAR HISTONES IN PIG-TO-BABOON ORGAN XENOTRANSPLANTATION

1
1. scibot 20 Apr 2023
  
  in Public
  
  nti-CD40mAb (2C10R4; NIH NHP Reagent Resource
  
  DOI: 10.1097/TP.0000000000001676
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5856196/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pre-clinical results in pig-to-nonhuman primate islet xenotransplantation using anti-CD40 antibody (2C10R4)-based immunosuppression

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 mAb (2C10R4, NIH NHP Reagent Resource
  
  DOI: 10.1111/xen.12356
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5809197/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Delayed revascularization of islet after transplantation by IL-6 blockade in pig to nonhuman primate islet xenotransplantation model

1
1. scibot 20 Apr 2023
  
  in Public
  
  anti-CD40 mAb (2C10R4, NIH NHP Reagent Resource
  
  DOI: 10.1111/xen.12374
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC5903442/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model

1
1. scibot 20 Apr 2023
  
  in Public
  
  Both 2C10R4 and ICOS-Ig were obtained from NIH Nonhuman Primate Reagent Resource
  
  DOI: 10.1097/TXD.0000000000000761
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5811273/
www.nature.com www.nature.com

Consistent success in life-supporting porcine cardiac xenotransplantation

1
1. scibot 19 Apr 2023
  
  in Public
  
  anti-CD40 monoclonal antibody (mouse/rhesus chimeric IgG4 clone 2C10R4, NIH Non-human Primate Reagent Resource
  
  DOI: 10.1038/s41586-018-0765-z
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

nature.com/articles/s41586-018-0765-z
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure

1
1. scibot 18 Apr 2023
  
  in Public
  
  Anti-CD40mAb (2C10R4, a chimeric rhesus IgG4) was provided by the NIH NHP Reagent Resource
  
  DOI: 10.3389/fimmu.2021.788949
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
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RRID:AB_2716325

RRIDCUR:Missing

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8692283/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

“You cannot stay in the laboratory forever”*: Taking pig kidney xenotransplantation from the laboratory to the clinic

1
1. scibot 18 Apr 2023
  
  in Public
  
  Anti-CD40 monoclonal antibody (mAb) (2C10R4, a chimeric rhesus IgG4) (NIH NHP Resource Center, Boston, MA)
  
  DOI: 10.1016/j.ebiom.2021.103562
  
  Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-4047, RRID:AB_2716325)
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:AB_2716325
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2716325
Visit annotations in context

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RRID:AB_2716325

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8441149/