23 Matching Annotations
  1. Nov 2023
  2. www.science.org www.science.org
    Evaluation of an antibody to α4β7 in the control of SIVmac239-nef-stop infection
    1
    1. scibot 03 Nov 2023
      Summary

      DOI: 10.1126/science.aav6695

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    science.org/doi/10.1126/science.aav6695
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of Therapeutic Efficacy of an Anti-α4β7 Antibody in SIVmac251-Infected Rhesus Macaques
    1
    1. scibot 03 Nov 2023
      anti-α4β7 antibody (8) (Clone #A4B7, primatized ACT1

      DOI: 10.1126/science.aaw8562

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6768629/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking of α4β7 Gut-Homing Integrin during Acute Infection Leads to Decreased Plasma and Gastrointestinal Tissue Viral Loads in Simian Immunodeficiency Virus-Infected Rhesus Macaques
    1
    1. scibot 03 Nov 2023
      anti-α4β7

      DOI: 10.4049/jimmunol.1003052

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC3691699/
  5. Oct 2023
  6. www.science.org www.science.org
    Evaluation of an antibody to α4β7 in the control of SIVmac239-nef-stop infection
    1
    1. scibot 25 Oct 2023
      Supplementary

      DOI: 10.1126/science.aav6695

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1117, RRID:AB_2716330)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716330

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      RRID:AB_2716330 RRID:AB_2819257 RRID:AB_2716326
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    science.org/doi/10.1126/science.aav6695
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques
    1
    1. scibot 25 Oct 2023
      anti-α4β7

      DOI: 10.3389/fimmu.2020.01275

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC7379916/
  8. www.nature.com www.nature.com
    Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection
    1
    1. scibot 25 Oct 2023
      anti-α4β7 mAb

      DOI: 10.1038/nm.3715

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    nature.com/articles/nm.3715
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking α4β7 integrin binding to SIV does not improve virologic control
    1
    1. scibot 25 Oct 2023
      anti-α4β7

      DOI: 10.1126/science.aaw7765

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC9513815/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preferential Small Intestine Homing and Persistence of CD8 T Cells in Rhesus Macaques Achieved by Molecularly Engineered Expression of CCR9 and Reduced Ex Vivo Manipulation
    1
    1. scibot 25 Oct 2023
      α4β7 antibody, number PR-1427

      DOI: 10.1128/JVI.00896-19

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6803279/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques
    1
    1. scibot 25 Oct 2023
      anti-α4β7 (Act-1

      DOI: 10.1128/mSphere.00824-19

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6908426/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques
    1
    1. scibot 25 Oct 2023
      α4β7

      DOI: 10.1089/aid.2018.0180

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6434602/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Experimental Infection of Cynomolgus Macaques (Macaca fascicularis) with Human Varicella-Zoster Virus
    1
    1. scibot 25 Oct 2023
      α4β7

      DOI: 10.1128/JVI.06264-11

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC3302534/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early treatment with anti-α4β7 antibody facilitates increased gut macrophage maturity in SIV-infected rhesus macaques
    1
    1. scibot 24 Oct 2023
      anti-α4β7 mAb

      DOI: 10.3389/fimmu.2022.1001727

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC9664000/
  15. Jun 2023
  16. insight.jci.org insight.jci.org
    IL-21 enhances influenza vaccine responses in aged macaques with suppressed SIV infection
    1
    1. scibot 15 Jun 2023
      α4β7

      DOI: 10.1172/jci.insight.150888

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRIDCUR:Missing RRID:AB_2716326
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    insight.jci.org/articles/view/150888
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies
    1
    1. scibot 15 Jun 2023
      Rh-α4β7

      DOI: 10.1126/scitranslmed.abf7201

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRIDCUR:Missing RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC8977869/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7
    1
    1. scibot 14 Jun 2023
      Anti-α4β7

      DOI: 10.1371/journal.ppat.1007278

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6130882/
  19. Apr 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin α4β7 blockade preferentially impacts CCR6+ lymphocyte subsets in blood and mucosal tissues of naive rhesus macaques
    1
    1. scibot 22 Apr 2023
      Rh-α4β7 antibody (clone Act-1; NIH Nonhuman Primate Reagents Resource center

      DOI: 10.4049/jimmunol.1701150

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1422, RRID:AB_2819258)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2819258

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      RRID:AB_2819258 RRID:AB_2716326 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC5760460/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3
    1
    1. scibot 20 Apr 2023
      α4β7 (Act-1, NHP-repository

      DOI: 10.1371/journal.ppat.1005720

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRIDCUR:Missing RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC4922556/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Th1 biased Tfh (Tfh1 cells) in lymphoid tissues during chronic SIV infection defines functionally distinct germinal center Tfh cells
    1
    1. scibot 20 Apr 2023
      α4β7 (Act1, NHP reagent resource)

      DOI: 10.4049/jimmunol.1600143

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRIDCUR:Missing RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC4992610/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection
    1
    1. scibot 19 Apr 2023
      Anti α4β7 mAb, rhesus IgG mAb and anti-CD4 (Fab)2 provided by the NIH Nonhuman Primate Reagents Resource

      DOI: 10.1038/mi.2017.112

      Resource: AB_2716330

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716330

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      RRIDCUR:Missing RRID:AB_2716330 RRID:AB_2819255 RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC5976508/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional MAIT Cells Are Associated With Reduced Simian–Human Immunodeficiency Virus Infection
    1
    1. scibot 19 Apr 2023
      α4β7 (Act1, NHP reagent resource

      DOI: 10.3389/fimmu.2019.03053

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRIDCUR:Missing RRID:AB_2716326
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    ncbi.nlm.nih.gov/pmc/articles/PMC6978843/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV‐infected rhesus macaques
    1
    1. scibot 18 Apr 2023
      anti‐α4β7 Ab (NHP reagents)

      DOI: 10.1096/fj.202002235R

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC7839271/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies
    1
    1. scibot 18 Apr 2023
      Rh-α4β7 antibody can be purchased from the Nonhuman Primate Reagent Resource of MassBiologics at www.nhpreagents.org/

      DOI: 10.1126/scitranslmed.abf7201

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC8977869/
  27. insight.jci.org insight.jci.org
    IL-21 enhances influenza vaccine responses in aged macaques with suppressed SIV infection
    1
    1. scibot 18 Apr 2023
      α4β7 (A4B7, NHP Reagent Resource

      DOI: 10.1172/jci.insight.150888

      Resource: (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)

      Curator: @Apiekniewska

      SciCrunch record: RRID:AB_2716326

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      RRID:AB_2716326 RRIDCUR:Missing
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    insight.jci.org/articles/view/150888