29 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.bcp.2024.116198

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    sciencedirect.com/science/article/pii/S0006295224001813
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
    2
    1. scibot 19 Mar 2024
      RRID:AB_2716685

      DOI: 10.1016/j.molcel.2024.02.035

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    2. scibot 19 Mar 2024
      RRID:AB_2716685

      DOI: 10.1016/j.molcel.2024.02.035

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    sciencedirect.com/science/article/pii/S109727652400176X
  5. Oct 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
    1
    1. scibot 20 Oct 2023
      RRID:AB_2716685

      DOI: 10.1158/0008-5472.CAN-22-1337

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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  7. Sep 2023
  8. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
    1
    1. scibot 12 Sep 2023
      RRID: AB_2716685

      DOI: 10.15252/embr.202356948

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      Curator: @jmitrevska

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    embopress.org/doi/full/10.15252/embr.202356948
  9. Aug 2023
  10. link.springer.com link.springer.com
    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
    1
    1. scibot 16 Aug 2023
      RRID:AB_2716685

      DOI: 10.1007/s10967-023-09067-0

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    link.springer.com/article/10.1007/s10967-023-09067-0
  11. 52.53.155.43 52.53.155.43
    PIIS2211124723009543-html.html
    1
    1. scibot 12 Aug 2023
      RRID:AB_2716685

      DOI: 10.1016/j.celrep.2023.112943

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    52.53.155.43/7a7cd2b37d518c0daab3f29f5b28b810c1030ef5/PIIS2211124723009543-html.html
  12. Apr 2023
  13. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
    1
    1. scibot 08 Apr 2023
      RRID:AB_2716685

      DOI: 10.1016/j.xcrm.2023.101007

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    sciencedirect.com/science/article/pii/S2666379123001179
  14. Feb 2023
  15. www.sciencedirect.com www.sciencedirect.com
    IFNγ signaling sensitizes melanoma cells to BH3 Mimetics
    1
    1. scibot 04 Feb 2023
      RRID:AB_2716685

      DOI: 10.1016/j.jid.2023.01.017

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    sciencedirect.com/science/article/pii/S0022202X23000726
  16. Jan 2023
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
    1
    1. scibot 10 Jan 2023
      RRID:AB_2716685

      DOI: 10.1111/jnc.15751

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15751
  18. Nov 2022
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
    1
    1. scibot 19 Nov 2022
      RRID:AB_2716685

      DOI: 10.1158/2767-9764.crc-22-0024

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
    1
    1. scibot 18 Nov 2022
      RRID:AB_2716685

      DOI: 10.1016/j.isci.2022.105458

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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  21. Oct 2022
  22. www.sciencedirect.com www.sciencedirect.com
    MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
    1
    1. scibot 05 Oct 2022
      RRID:AB_2716685

      DOI: 10.1016/j.celrep.2022.111445

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    sciencedirect.com/science/article/pii/S2211124722012864
  23. Aug 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
    1
    1. scibot 23 Aug 2022
      RRID:AB_2716685

      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  25. Jul 2022
  26. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
    1
    1. scibot 29 Jul 2022
      RRID:AB_2716685

      DOI: 10.1158/2767-9764.CRC-22-0024

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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  27. May 2022
  28. journals.sagepub.com journals.sagepub.com
    Cathepsin B Relocalization in Late Membrane Disrupted Neurons Following Diffuse Brain Injury in Rats - Martina L. Hernandez, Michael Marone, Karen M. Gorse, Audrey D. Lafrenaye, 2022
    1
    1. scibot 10 May 2022
      RRID:AB_2716685

      DOI: 10.1177/17590914221099112

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    journals.sagepub.com/doi/full/10.1177/17590914221099112
  29. Apr 2022
  30. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
    1
    1. scibot 26 Apr 2022
      RRID:AB_2716685

      DOI: 10.1007/s11010-022-04433-0

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    link.springer.com/article/10.1007/s11010-022-04433-0
  31. Mar 2022
  32. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
    1
    1. scibot 11 Mar 2022
      RRID:AB_2716685

      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  33. Nov 2021
  34. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
    1
    1. scibot 24 Nov 2021
      RRID:AB_2716685

      DOI: 10.1158/1535-7163.MCT-21-0089

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    mct.aacrjournals.org/content/20/11/2151
  35. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      RRID:AB_2716685

      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
  36. Aug 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
    1
    1. scibot 16 Aug 2021
      RRID:AB_2716685

      DOI: 10.1016/j.ccell.2021.07.006

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    sciencedirect.com/science/article/pii/S1535610821003834
  38. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
      RRID:AB_2716685

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  39. Apr 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    1. scibot 22 Apr 2021
      RRID:AB_271685

      DOI: 10.1016/j.ccell.2020.10.010

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      Curator: @Naa003

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      Curator comments: Bak (D4E4) Rabbit mAb antibody Cell Signaling Technology Cat# 12105

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    sciencedirect.com/science/article/pii/S1535610820305419
  41. Sep 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
    1
    1. scibot 23 Sep 2020
      RRID:AB_2716685

      DOI: 10.1016/j.immuni.2020.01.014

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S107476132030042X
  43. www.sciencedirect.com www.sciencedirect.com
    Microarray assay of circular RNAs reveals cicRNA.7079 as a new anti-apoptotic molecule in spinal cord injury in mice
    1
    1. scibot 05 Sep 2020
      RRID:AB_2716685

      DOI: 10.1016/j.brainresbull.2020.08.004

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      RRIDCUR:Validated RRID:AB_2716685
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    sciencedirect.com/science/article/pii/S0361923020305852
  44. Jan 2020
  45. www.sciencedirect.com www.sciencedirect.com
    The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
    1
    1. scibot 13 Jan 2020
      RRID:AB_2716685

      DOI: 10.1016/j.cell.2019.05.035

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      Curator: @ethanbadger

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      RRID:AB_2716685 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741930563X
  46. www.sciencedirect.com www.sciencedirect.com
    BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
    1
    1. scibot 13 Jan 2020
      RRID:AB_2716685

      DOI: 10.1016/j.ccell.2019.04.005

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      Curator: @ethanbadger

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      RRID:AB_2716685 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819302004
  47. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2716685

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  48. Nov 2018
  49. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    1. scibot 05 Nov 2018
      RRID:AB_2716685

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    sciencedirect.com/science/article/pii/S1535610817305020