22 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Farnesyl Transferase Inhibitor KO-2806 (Darlifarnib) Enhances the Antitumor Activity of Tyrosine Kinase Inhibitors in RCC
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13535317/
  3. Oct 2025
  4. www.sciencedirect.com www.sciencedirect.com
    HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725011532
  5. Aug 2025
  6. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017158-main-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/d86d60ff30b3ad94317a5f54629a255673424141/1-s2.0-S2589004225017158-main-html.html
  7. Jul 2025
  8. www.science.org www.science.org
    Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/science.adm9805
  9. Feb 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11832924/
  11. Dec 2024
  12. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724014529
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
  15. Feb 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10831937/
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0021925824000176
  19. Dec 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Ring domains are essential for GATOR2-dependent mTORC1 activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522011340
  21. Nov 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9648415/
  23. Sep 2022
  24. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
  25. Nov 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
  27. Aug 2021
  28. academic.oup.com academic.oup.com
    Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/biolreprod/article/99/6/1289/5046413
  29. May 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520306870
  31. www.sciencedirect.com www.sciencedirect.com
    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580720306304
  32. Apr 2021
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
  34. Mar 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521000095
  36. Nov 2020
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7661039/
  38. Sep 2020
  39. www.sciencedirect.com www.sciencedirect.com
    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720305209
  40. Nov 2018
  41. academic.oup.com academic.oup.com
    Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/biolreprod/article/99/6/1289/5046413
  42. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867418305865