20 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017158-main-html.html
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    52.53.155.43/d86d60ff30b3ad94317a5f54629a255673424141/1-s2.0-S2589004225017158-main-html.html
  3. Jul 2025
  4. www.science.org www.science.org
    Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
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    science.org/doi/10.1126/science.adm9805
  5. Feb 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832924/
  7. Dec 2024
  8. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    sciencedirect.com/science/article/pii/S2211124724014529
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10920058/
  11. Feb 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831937/
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    sciencedirect.com/science/article/pii/S0021925824000176
  15. Dec 2022
  16. www.sciencedirect.com www.sciencedirect.com
    Ring domains are essential for GATOR2-dependent mTORC1 activation
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    sciencedirect.com/science/article/pii/S1097276522011340
  17. Nov 2022
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9648415/
  19. Sep 2022
  20. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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    aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
  21. Nov 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
  23. Aug 2021
  24. academic.oup.com academic.oup.com
    Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis
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    academic.oup.com/biolreprod/article/99/6/1289/5046413
  25. May 2021
  26. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
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    sciencedirect.com/science/article/pii/S1097276520306870
  27. www.sciencedirect.com www.sciencedirect.com
    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
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    sciencedirect.com/science/article/pii/S1534580720306304
  28. Apr 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
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    ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
  30. Mar 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling
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    sciencedirect.com/science/article/pii/S1097276521000095
  32. Nov 2020
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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    ncbi.nlm.nih.gov/pmc/articles/PMC7661039/
  34. Sep 2020
  35. www.sciencedirect.com www.sciencedirect.com
    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
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    sciencedirect.com/science/article/pii/S2211124720305209
  36. Nov 2018
  37. academic.oup.com academic.oup.com
    Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis
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    academic.oup.com/biolreprod/article/99/6/1289/5046413
  38. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    sciencedirect.com/science/article/pii/S0092867418305865