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Sep 2026
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RpS19a depletion alters the hematopoietic translatome to drive tissue overgrowth

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Aug 2026
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A tumour-host feed-forward loop contributes to the growth of chromosomal instability-induced tumours

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Tumors exploit interclonal Hedgehog-Wnt crosstalk to drive tumor-promoting cell competition

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  DOI: 10.1016/j.devcel.2026.07.018
  
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An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

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54.241.53.176/6d9de9560e18dc1772c142fd048e71fe9aa1ba15/PMID_39226333-html.html
Jul 2026
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Tumor-derived Ilp8 and Upd3 contribute to intestinal progenitor cells depletion during cachexia in Drosophila larvae

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sciencedirect.com/science/article/pii/S2211124726008004
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Asperous coordinates regeneration timing by regulating damage-induced WNT signaling

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Orb2 RNA-binding activity promotes neural stem cell development and brain growth in Drosophila larvae

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cell.com/cell-reports/fulltext/S2211-1247(26)00758-8
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journal.pgen.1011387.s009-html.html

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54.241.53.176/6baf3e6a8c7a828ab95a4371c54a0422dad9c85f/journal.pgen.1011387.s009-html.html
Jun 2026
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Tracheal terminal cells of Drosophila are immune privileged to maintain their Foxo-dependent structural plasticity

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1. scibot 19 Jun 2026
  
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  DOI: 10.7554/eLife.102369
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13275064/
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Preconception e-nicotine impairs airway development and progenitor proliferation across generations in Drosophila Melanogaster

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  DOI: 10.64898/2026.06.08.730871
  
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biorxiv.org/content/10.64898/2026.06.08.730871v1
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Developmental and age-related synapse elimination is mediated by glial Croquemort

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1. scibot 09 Jun 2026
  
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  DOI: 10.1016/j.neuron.2026.04.046
  
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May 2026
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Ablation of the adhesion G protein-coupled receptor ADGRL1 activates anti-tumor immune response via cDC1-T cell hub formation

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1. scibot 27 May 2026
  
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RpS12-mediated induction of the Xrp1short isoform links ribosomal protein mutations to cell competition

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1. scibot 27 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117380
  
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Proteostasis failure and mitochondrial dysfunction contribute to chromosomal instability-induced microcephaly

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1. scibot 09 May 2026
  
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54.241.53.176/cbb8d0fde67f74a17eee22abf8e82daaf2badce4/PMID_41820377-html.html
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Tsc1 and Tsc2 maintain hematopoietic homeostasis through multiple signaling pathways in Drosophila

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.yexcr.2026.115060
  
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sciencedirect.com/science/article/pii/S0014482726001771
Mar 2026
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Cellular fitness is determined by ribosomal protein S12-mediated release of a truncated Xrp1

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1. scibot 27 Mar 2026
  
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2026.02.24.707778.full-html.html

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54.241.53.176/39776fbe0c11e0526b108f024a12917f20d83641/2026.02.24.707778.full-html.html
Feb 2026
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Single-cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location

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1. scibot 07 Feb 2026
  
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  DOI: 10.7554/eLife.106410
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12872174/
Jan 2026
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α-Ketoglutarate couples cellular metabolism to developmental growth via hydroxylation-dependent degradation of Yorkie

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116922
  
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Dec 2025
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Post-transcriptional suppression of the pioneer factor Zelda protects the adult Drosophila testis from activation of the ovary program

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1. scibot 31 Dec 2025
  
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54.241.53.176/f29d4b43b8f645408b46ba6a56176a699c42bb50/PMID_41411219-html.html
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X chromosome dosage in respiratory stem cells is critical for post-embryonic development and survival

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Nov 2025
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Neuronal Selection Based on Relative Fitness Comparison Detects and Eliminates Amyloid-β-Induced Hyperactive Neurons in Drosophila

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EyaHOST, a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster

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  DOI: 10.1016/j.crmeth.2025.101220
  
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The directionality of collective cell delamination is governed by tissue architecture and cell adhesion in a Drosophila carcinoma model

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  DOI: 10.1016/j.isci.2025.113663
  
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Oct 2025
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1-s2.0-S2589004225019248-main-html.html

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Sep 2025
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Pp1-87B/PPP1CC-JNK axis integrates apoptosis and ferroptosis-like cell death to regulate cell competition and tumorigenesis

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116240
  
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Aug 2025
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zhao-et-al-hemocytes-facilitate-interclonal-cooperation-induced-tumor-malignancy-by-hijacking-the-innate-immune-system-html.html

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1. scibot 27 Aug 2025
  
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54.241.53.176/7da1eb3af3e6ce644fa025de82baea3bf865997c/Book3-html.html
Jul 2025
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Organization of the apical extracellular matrix during tubular organ formation

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1. scibot 31 Jul 2025
  
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  DOI: 10.1101/2024.11.20.624565
  
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52.53.155.43/b87ae6c5bb2b80916f5a5bf04a5ce543409a2e6c/NIHPP2024.11.20.624565v2-supplement-2-html.html
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Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila

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  DOI: 10.1016/j.devcel.2025.06.036
  
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1-s2.0-S2589004225013963-main-html.html

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Jun 2025
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kong-et-al-adipose-tissue-secreted-spz5-promotes-distal-tumor-progression-via-toll-6-mediated-hh-pathway-activation-in-html.html

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1. scibot 28 Jun 2025
  
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  DOI: 10.1038/s44318-025-00489-y
  
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52.53.155.43/f797b68cc578c5707d96baf6b2dcdbd6b1b6aadb/kong-et-al-adipose-tissue-secreted-spz5-promotes-distal-tumor-progression-via-toll-6-mediated-hh-pathway-activation-in-html.html
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Adipose tissue-secreted Spz5 promotes distal tumor progression via Toll-6-mediated Hh pathway activation in Drosophila

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1. scibot 28 Jun 2025
  
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embopress.org/doi/10.1038/s44318-025-00489-y
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Macrophages promote tumor growth by phagocytosis-mediated cytokine amplification in Drosophila

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.cub.2025.05.068
  
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Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling

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Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila

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Activation of the Drosophila innate immune system accelerates growth in cooperation with oncogenic Ras

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1-s2.0-S258900422500848X-main-html.html

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Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition

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PDF-html.html

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Olfactory inputs regulate Drosophila melanogaster oogenesis

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The directionality of collective cell delamination is governed by tissue architecture and cell adhesion in a Drosophila carcinoma model

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Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons

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The mechanical state of pre-tumoral epithelia controls subsequent Drosophila tumor aggressiveness

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Flamingo participates in multiple models of cell competition

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Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity

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Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways

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wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html

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The role of Imp and Syp RNA-binding proteins in precise neuronal elimination by apoptosis through the regulation of transcription factors

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Notch signaling promotes differentiation, cell death and autophagy in Drosophila hematopoietic system

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EGFR signaling coordinates patterning with cell survival during Drosophila epidermal development

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Autocrine glutamate signaling drives cell competition in Drosophila

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A hierarchical transcription factor cascade regulates enteroendocrine cell diversity and plasticity in Drosophila

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Piezo regulates epithelial topology and promotes precision in organ size control

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esteban-collado-et-al-2024-reactive-oxygen-species-activate-the-drosophila-tnf-receptor-wengen-for-damage-induced-html.html

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Reactive oxygen species activate the Drosophila TNF receptor Wengen for damage-induced regeneration

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Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8

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The Drosophila EcR-Hippo component Taiman promotes epithelial cell fitness by control of the Dally-like glypican and Wg gradient

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Odorant receptor co-receptors affect expression of tuning receptors in Drosophila

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An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

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Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation

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Early-wave macrophages control late hematopoiesis

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Xrp1 governs the stress response program to spliceosome dysfunction

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Parasitoid cues modulate Drosophila germline development and stem cell proliferation

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A mismatch in the expression of cell surface molecules induces tissue-intrinsic defense against aberrant cells

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Patterned apoptosis has an instructive role for local growth and tissue shape regulation in a fast-growing epithelium

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Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells

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Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint

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Differential Ire1 determines loser cell fate in tumor-suppressive cell competition

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Chromosomal instability-induced cell invasion through caspase-driven DNA damage

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E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation

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A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan

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Nuclear receptors EcR-A/RXR and HR3 control early embryogenesis in the short-germ hemimetabolous insect Blattella germanica

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Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex

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Xrp1 governs the stress response program to spliceosome dysfunction

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Coordinated growth of linked epithelia is mediated by the Hippo pathway

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Downregulation of oxidative stress-mediated glial innate immune response suppresses seizures in a fly epilepsy model

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Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size

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A hierarchical transcription factor cascade regulates enteroendocrine cell diversity and plasticity in Drosophila

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Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs

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Fat body-derived Spz5 remotely facilitates tumor-suppressive cell competition through Toll-6-α-Spectrin axis-mediated Hippo activation

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Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila

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Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila

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ROS Inhibits Cell Growth by Regulating 4EBP and S6K, Independent of TOR, during Development

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Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila

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Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation

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Condensation of the Drosophila nerve cord is oscillatory and depends on coordinated mechanical interactions

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FEBS Press

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The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function

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Yorkie drives supercompetition by non-autonomous induction of autophagy via bantam microRNA in Drosophila

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chinmo-mutant spermatogonial stem cells cause mitotic drive by evicting non-mutant neighbors from the niche

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Chemical Genetic Screen in Drosophila Germline Uncovers Small Molecule Drugs That Sensitize Stem Cells to Insult-Induced Apoptosis

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Sequential oncogenic mutations influence cell competition

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Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition

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Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila

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Untitled document

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Optimal searching behaviour generated intrinsically by the central pattern generator for locomotion

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mastermind regulates niche ageing independently of the Notch pathway in the Drosophila ovary

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Untitled document

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Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence

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Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth

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A transitory signaling center controls timing of primordial germ cell differentiation

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Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

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Identification of functionally distinct macrophage subpopulations in Drosophila

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Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies

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Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia

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A Progressive Somatic Cell Niche Regulates Germline Cyst Differentiation in the Drosophila Ovary

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Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment

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Ecd promotes U5 snRNP maturation and Prp8 stability

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Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells

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Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments

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Extensive and diverse patterns of cell death sculpt neural networks in insects

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Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation

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Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses

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Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8

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The Drosophila Ortholog of Mammalian Transcription Factor Sox9 Regulates Intestinal Homeostasis and Regeneration at an Appropriate Level

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Hyperinsulinemia Drives Epithelial Tumorigenesis by Abrogating Cell Competition

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Local Necrotic Cells Trigger Systemic Immune Activation via Gut Microbiome Dysbiosis in Drosophila

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Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia

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Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin

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Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development

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Modular transcriptional programs separately define axon and dendrite connectivity

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Cell Competition Is Driven by Autophagy

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Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors

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Ets21c Governs Tissue Renewal, Stress Tolerance, and Aging in the Drosophila Intestine

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The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

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Mechanical Function of the Nucleus in Force Generation during Epithelial Morphogenesis

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The Taiman Transcriptional Coactivator Engages Toll Signals to Promote Apoptosis and Intertissue Invasion in Drosophila

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Selective Killing of RAS-Malignant Tissues by Exploiting Oncogene-Induced DNA Damage

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Cell-Size Pleomorphism Drives Aberrant Clone Dispersal in Proliferating Epithelia

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Oncogenic Notch Triggers Neoplastic Tumorigenesis in a Transition-Zone-like Tissue Microenvironment

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sciencedirect.com/science/article/pii/S2211124718318898
Nov 2018
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A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster

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Untitled document

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A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation

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Plasma Membrane Localization of Apoptotic Caspases for Non-apoptotic Functions

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Cell death in neural precursor cells and neurons before neurite formation prevents the emergence of abnormal neural structures in the Drosophila optic lobe

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The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia

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  Curator note: Cell Signaling Technology Cat# 9578' Cleaved Drosophila Dcp-1 (Asp216) Antibody
  
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