18 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
    1
    1. scibot 10 Apr 2024
      RRID:AB_2721109

      DOI: 10.1016/j.isci.2024.109524

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
  3. Feb 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2024.113845

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

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    sciencedirect.com/science/article/pii/S2211124724001736
  5. Oct 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA2 nuclease inhibition confers synthetic lethality in cancers with mutant p53 and synergizes with PARP inhibitors
    1
    1. scibot 18 Oct 2023
      RRID:AB_2721109

      DOI: 10.1158/2767-9764.CRC-23-0166

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    ncbi.nlm.nih.gov/pmc/articles/PMC10578204/
  7. www.sciencedirect.com www.sciencedirect.com
    Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair
    1
    1. scibot 14 Oct 2023
      RRID:AB_2721109

      DOI: 10.1016/j.molcel.2023.09.015

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

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    sciencedirect.com/science/article/abs/pii/S1097276523007347
  8. Aug 2023
  9. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      RRID:AB_2721109

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      RRID:AB_2721109

      DOI: 10.1016/j.xcrm.2023.101142

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  10. Apr 2023
  11. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
    1
    1. scibot 21 Apr 2023
      RRID:AB_2721109

      DOI: 10.1158/2326-6066.CIR-22-0056

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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
    1
    1. scibot 21 Apr 2023
      RRID:AB_2721109

      DOI: 10.1158/1078-0432.CCR-22-2977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  13. Dec 2022
  14. www.sciencedirect.com www.sciencedirect.com
    The ADP-ribose hydrolase NUDT5 is important for DNA repair
    1
    1. scibot 24 Dec 2022
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2022.111866

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    sciencedirect.com/science/article/pii/S2211124722017624
  15. Nov 2022
  16. www.sciencedirect.com www.sciencedirect.com
    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
    1
    1. scibot 10 Nov 2022
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2022.111600

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    sciencedirect.com/science/article/pii/S2211124722014656
  17. May 2022
  18. www.sciencedirect.com www.sciencedirect.com
    AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
    1
    1. scibot 26 May 2022
      RRID:AB_2721109

      DOI: 10.1016/j.isci.2022.104398

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    sciencedirect.com/science/article/pii/S2589004222006691
  19. Jan 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
    1
    1. scibot 22 Jan 2022
      RRID:AB_2721109

      DOI: 10.3390/cancers14020326

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    ncbi.nlm.nih.gov/pmc/articles/PMC8773906/
  21. Jul 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    1
    1. scibot 22 Jul 2021
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2021.109394

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    sciencedirect.com/science/article/pii/S2211124721007920
  23. Sep 2020
  24. www.sciencedirect.com www.sciencedirect.com
    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection
    1
    1. scibot 23 Sep 2020
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2020.01.052

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

      Curator: @ethanbadger

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      RRID:AB_2721109 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720300772
  25. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
    1
    1. scibot 04 Sep 2020
      RRID:AB_2721109

      DOI: 10.1158/0008-5472.CAN-19-1161

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

      Curator: @ethanbadger

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      RRID:AB_2721109 RRIDCUR:Validated
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    cancerres.aacrjournals.org/content/80/2/334
  26. Jan 2020
  27. www.sciencedirect.com www.sciencedirect.com
    Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase
    1
    1. scibot 13 Jan 2020
      RRID:AB_2721109

      DOI: 10.1016/j.canlet.2019.05.027

      Resource: (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

      Curator: @ethanbadger

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      RRID:AB_2721109 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0304383519303222
  28. Nov 2018
  29. www.cell.com www.cell.com
    EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma
    1
    1. scibot 05 Nov 2018
      RRID:AB_2721109

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    cell.com/cancer-cell/fulltext/S1535-6108(17)30561-5
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2721109

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      (Cell Signaling Technology Cat# 8875, RRID:AB_2721109)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/