23 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
    1
    1. scibot 14 Jul 2024
      RRID:AB_2721109

      DOI: 10.1016/j.isci.2024.110180

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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  3. May 2024
  4. 52.53.155.43 52.53.155.43
    Mechanisms Driving Fasting-Induced Protection from Genotoxic Injury in the Small Intestine
    3
    1. scibot 24 May 2024
      RRID:AB_2721109

      DOI: 10.1152/ajpgi.00126.2023

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    2. scibot 24 May 2024
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      DOI: 10.1152/ajpgi.00126.2023

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    3. scibot 24 May 2024
      RRID:AB_2721109

      DOI: 10.1152/ajpgi.00126.2023

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    52.53.155.43/930a5a5a8b2489c0ec72d025108e06cc5c87d2d2/deans-fielder-et-al-2024-mechanisms-driving-fasting-induced-protection-from-genotoxic-injury-in-the-small-intestine-html.html
  5. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
    1
    1. scibot 23 May 2024
      RRID:AB_2721109

      DOI: 10.1016/j.xcrm.2024.101578

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    sciencedirect.com/science/article/pii/S2666379124002702
  6. Apr 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
    1
    1. scibot 10 Apr 2024
      RRID:AB_2721109

      DOI: 10.1016/j.isci.2024.109524

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993188/
  8. Feb 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2024.113845

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    sciencedirect.com/science/article/pii/S2211124724001736
  10. Oct 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA2 nuclease inhibition confers synthetic lethality in cancers with mutant p53 and synergizes with PARP inhibitors
    1
    1. scibot 18 Oct 2023
      RRID:AB_2721109

      DOI: 10.1158/2767-9764.CRC-23-0166

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    ncbi.nlm.nih.gov/pmc/articles/PMC10578204/
  12. www.sciencedirect.com www.sciencedirect.com
    Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair
    1
    1. scibot 14 Oct 2023
      RRID:AB_2721109

      DOI: 10.1016/j.molcel.2023.09.015

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    sciencedirect.com/science/article/abs/pii/S1097276523007347
  13. Aug 2023
  14. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      RRID:AB_2721109

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      RRID:AB_2721109

      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  15. Apr 2023
  16. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
    1
    1. scibot 21 Apr 2023
      RRID:AB_2721109

      DOI: 10.1158/2326-6066.CIR-22-0056

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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
    1
    1. scibot 21 Apr 2023
      RRID:AB_2721109

      DOI: 10.1158/1078-0432.CCR-22-2977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  18. Dec 2022
  19. www.sciencedirect.com www.sciencedirect.com
    The ADP-ribose hydrolase NUDT5 is important for DNA repair
    1
    1. scibot 24 Dec 2022
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2022.111866

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    sciencedirect.com/science/article/pii/S2211124722017624
  20. Nov 2022
  21. www.sciencedirect.com www.sciencedirect.com
    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
    1
    1. scibot 10 Nov 2022
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2022.111600

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    sciencedirect.com/science/article/pii/S2211124722014656
  22. May 2022
  23. www.sciencedirect.com www.sciencedirect.com
    AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
    1
    1. scibot 26 May 2022
      RRID:AB_2721109

      DOI: 10.1016/j.isci.2022.104398

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    sciencedirect.com/science/article/pii/S2589004222006691
  24. Jan 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
    1
    1. scibot 22 Jan 2022
      RRID:AB_2721109

      DOI: 10.3390/cancers14020326

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    ncbi.nlm.nih.gov/pmc/articles/PMC8773906/
  26. Jul 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    1
    1. scibot 22 Jul 2021
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2021.109394

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    sciencedirect.com/science/article/pii/S2211124721007920
  28. Sep 2020
  29. www.sciencedirect.com www.sciencedirect.com
    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection
    1
    1. scibot 23 Sep 2020
      RRID:AB_2721109

      DOI: 10.1016/j.celrep.2020.01.052

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      RRID:AB_2721109 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720300772
  30. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
    1
    1. scibot 04 Sep 2020
      RRID:AB_2721109

      DOI: 10.1158/0008-5472.CAN-19-1161

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    cancerres.aacrjournals.org/content/80/2/334
  31. Jan 2020
  32. www.sciencedirect.com www.sciencedirect.com
    Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase
    1
    1. scibot 13 Jan 2020
      RRID:AB_2721109

      DOI: 10.1016/j.canlet.2019.05.027

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      RRID:AB_2721109 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0304383519303222
  33. Nov 2018
  34. www.cell.com www.cell.com
    EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma
    1
    1. scibot 05 Nov 2018
      RRID:AB_2721109

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    cell.com/cancer-cell/fulltext/S1535-6108(17)30561-5
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2721109

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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/