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Aug 2025
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Differential regulation of FADS2 by EZH2 reveals a metabolic vulnerability in ovarian cancer treatment

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.ebiom.2025.105879
  
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sciencedirect.com/science/article/pii/S2352396425003238
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Matrix Stiffness Regulates TGFβ1‐Induced αSMA Expression via a G9a‐LATS‐YAP Signaling Cascade

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  DOI: 10.1096/fba.2025-00117
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12256985/
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Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115636
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12258067/
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Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation

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1. scibot 15 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-23-0613
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11543919/
Jun 2025
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EHMT1/2 inhibition promotes regression of therapy-resistant ovarian cancer tumors in a CD8 T cell-dependent manner

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  DOI: 10.1158/1541-7786.MCR-24-0067
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11614706/
May 2025
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CDK4 loss-of-function mutations cause microcephaly and short stature

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1. scibot 20 May 2025
  
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  DOI: 10.1101/gad.352311.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617628/
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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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  DOI: 10.1016/j.celrep.2025.115632
  
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sciencedirect.com/science/article/pii/S2211124725004036
Mar 2025
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1-s2.0-S2589004225004419-main (1)-html.html

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1. scibot 13 Mar 2025
  
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  DOI: 10.1016/j.isci.2025.112180
  
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52.53.155.43/be6baf25cfa7bed532bea52b8835b3f02cde3216/1-s2.0-S2589004225004419-main (1)-html.html
Feb 2025
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Tenascin-C Potentiates Wnt Signaling in Thyroid Cancer

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1. scibot 23 Feb 2025
  
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  DOI: 10.1210/endocr/bqaf030
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11843548/
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Phospho-relay feedback loops control egress vs. intracellular development in Toxoplasma gondii

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  DOI: 10.1016/j.celrep.2025.115260
  
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sciencedirect.com/science/article/pii/S2211124725000312
Jan 2025
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Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs

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1. scibot 09 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115092
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831618/
Dec 2024
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Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114997
  
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sciencedirect.com/science/article/pii/S2211124724013482
Nov 2024
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Targeting BRPF3 moderately reverses olaparib resistance in high grade serous ovarian carcinoma

1
1. scibot 07 Nov 2024
  
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  DOI: 10.1002/mc.23610
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10592327/
Oct 2024
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QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction

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1. scibot 01 Oct 2024
  
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  DOI: 10.1038/s41467-024-52587-w
  
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nature.com/articles/s41467-024-52587-w
Sep 2024
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eIF2B localisation and its regulation during the integrated stress response is cell-type specific

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110851
  
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sciencedirect.com/science/article/pii/S2589004224020765
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Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells

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1. scibot 05 Sep 2024
  
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  DOI: 10.1152/ajpcell.00091.2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11371324/
Aug 2024
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Tumor intrinsic activity of Chromobox 2 (CBX2) remodels the tumor microenvironment in high grade serous carcinoma

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1. scibot 19 Aug 2024
  
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  DOI: 10.1158/2767-9764.CRC-24-0027
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11298703/
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VAP-mediated membrane-tethering mechanisms implicate ER-PM contact function in pH homeostasis

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114592
  
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sciencedirect.com/science/article/pii/S2211124724009215
Jul 2024
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Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis

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1. scibot 25 Jul 2024
  
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  DOI: 10.7554/eLife.64564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8149125/
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Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation

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  DOI: 10.1016/j.jbc.2024.107492
  
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sciencedirect.com/science/article/pii/S0021925824019938
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Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration

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  DOI: 10.1038/s41556-024-01453-4
  
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nature.com/articles/s41556-024-01453-4
Apr 2024
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The essential malaria protein PfCyRPA targets glycans to invade erythrocytes

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  DOI: 10.1016/j.celrep.2024.114012
  
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sciencedirect.com/science/article/pii/S2211124724003401
Mar 2024
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Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro

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1. scibot 27 Mar 2024
  
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  DOI: 10.1371/journal.pone.0299003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10962838/
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Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression

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1. scibot 20 Mar 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0513
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10946310/
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The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila

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  DOI: 10.1016/j.celrep.2023.113640
  
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Feb 2024
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Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway

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  DOI: 10.1101/2023.10.02.560521
  
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52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
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Pyruvate dehydrogenase kinase 2 knockdown restores the ability of amyotrophic lateral sclerosis-linked SOD1G93A rat astrocytes to support motor neuron survival by increasing mitochondrial respiration

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  DOI: 10.1002/glia.24516
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24516
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S100A4/NF-κB axis mediates the anticancer effect of epigallocatechin-3-gallate in platinum-resistant ovarian cancer

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  DOI: 10.1016/j.isci.2024.108885
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10835441/
Jan 2024
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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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1. scibot 24 Jan 2024
  
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  DOI: 10.1126/science.adi3448
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10801813/
Nov 2023
www.cell.com www.cell.com

Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

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  DOI: 10.1016/j.molcel.2023.10.020
  
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cell.com/molecular-cell/fulltext/S1097-2765(23)00857-2
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Impact of Mutations Defining SARS-CoV-2 Omicron Subvariants BA.2.12.1 and BA.4/5 on Spike Function and Neutralization

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  DOI: 10.1016/j.isci.2023.108299
  
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sciencedirect.com/science/article/pii/S2589004223023763
Oct 2023
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Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

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  DOI: 10.1016/j.chom.2023.08.018
  
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sciencedirect.com/science/article/pii/S1931312823003438
Sep 2023
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Intralumenal docking of Connexin 36 channels in the ER isolates mis-trafficked protein

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.jbc.2023.105282
  
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sciencedirect.com/science/article/pii/S0021925823023104
Aug 2023
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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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1. scibot 29 Aug 2023
  
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  DOI: 10.1126/science.adi3448
  
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science.org/doi/10.1126/science.adi3448
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Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells

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1. scibot 12 Aug 2023
  
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  AB_2721181
  
  DOI: 10.3389/fimmu.2023.1107397
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10407399/
Jul 2023
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CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement

1
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  DOI: 10.1016/j.cub.2023.06.079
  
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Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells

1
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  RRID:AB_2721181
  
  DOI: 10.1016/j.isci.2023.107232
  
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ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer

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  RRID:AB_2721181
  
  DOI: 10.1158/1541-7786.MCR-22-0102
  
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Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1

1
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  DOI: 10.1016/j.molcel.2023.06.007
  
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May 2023
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Actuation of single downstream nodes in growth factor network steers immune cell migration

1
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  RRID:AB_2721181
  
  DOI: 10.1016/j.devcel.2023.04.019
  
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Pervasive SUMOylation of heterochromatin and piRNA pathway proteins

1
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  RRID:AB_2721181
  
  DOI: 10.1016/j.xgen.2023.100329
  
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Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1

1
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  925-68071
  
  DOI: 10.1111/jnc.15277
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15277
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Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity

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  DOI: 10.1016/j.cmet.2023.04.015
  
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cell.com/cell-metabolism/fulltext/S1550-4131(23)00141-9
Apr 2023
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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities

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  DOI: 10.1016/j.ccell.2023.03.007
  
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Mar 2023
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Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation

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  DOI: 10.1038/s41586-023-05802-5
  
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nature.com/articles/s41586-023-05802-5
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Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models

1
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  RRID:AB_2721181
  
  DOI: 10.1101/2023.02.23.529773
  
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biorxiv.org/content/10.1101/2023.02.23.529773v1
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O-fucosylation of thrombospondin type I repeats is dispensable for trafficking thrombospondin 1 to platelet secretory granules

1
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  RRID:AB_2721181
  
  DOI: 10.1093/glycob/cwad006
  
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academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwad006/7017701
Feb 2023
elifesciences.org elifesciences.org

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

1
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  DOI: 10.7554/eLife.82207
  
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elifesciences.org/articles/82207
Dec 2022
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DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro

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  DOI: 10.3389/fgene.2022.1032958
  
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Nov 2022
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Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

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  DOI: 10.1016/j.cell.2022.10.003
  
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Oct 2022
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Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities

1
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  RRID:AB_2721181
  
  DOI: 10.1016/j.isci.2022.105189
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9579017/
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p300/CBP sustains Polycomb silencing by non-enzymatic functions

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  DOI: 10.1016/j.molcel.2022.09.005
  
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Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex

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Sep 2022
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Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells

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  DOI: 10.1016/j.neuron.2022.09.002
  
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Effects of HSD11B1 knockout and overexpression on local cortisol production and differentiation of mesenchymal stem cells

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  DOI: 10.3389/fbioe.2022.953034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9453430/
Aug 2022
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Distinct silencer states generate epigenetic states of heterochromatin

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Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: Implications for fetal alcohol spectrum disorders

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  DOI: 10.1016/j.alcohol.2022.07.007
  
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Determinants of Spike Infectivity, Processing and Neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2

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  DOI: 10.1016/j.chom.2022.07.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9289044/
Jul 2022
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From guide to guard—activation mechanism of the stress-sensing chaperone Get3

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  DOI: 10.1016/j.molcel.2022.06.015
  
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Jun 2022
elifesciences.org elifesciences.org

METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance

1
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  DOI: 10.7554/eLife.72780
  
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May 2022
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Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception

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  DOI: 10.1016/j.devcel.2022.05.001
  
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sciencedirect.com/science/article/pii/S153458072200329X
Mar 2022
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Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

1
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  DOI: 10.7554/eLife.73150
  
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Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition

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  DOI: 10.1002/jcp.30705
  
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japplphysiol.00536.2021-html.html

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  DOI: 10.1152/japplphysiol.00536.2021
  
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52.53.155.43/29de5e7222342c85eeeb25aa2522e8bbef77b2f2/japplphysiol.00536.2021-html.html
Feb 2022
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Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor

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  DOI: 10.1016/j.ebiom.2022.103872
  
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Jan 2022
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ACE2 can act as the secondary receptor in the FcγR-dependent ADE of SARS-CoV-2 infection

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  DOI: 10.1016/j.isci.2021.103720
  
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The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell

1
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  DOI: 10.7554/eLife.70451
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8687662/
Dec 2021
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Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I

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  DOI: 10.1016/j.chembiol.2021.11.002
  
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Oct 2021
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Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells

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Sep 2021
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An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins

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Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns

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Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells

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Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration

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Extracellular Vesicle‐Based Therapeutic Targeting of β‐Catenin to Modulate Anticancer Immune Responses in Hepatocellular Cancer

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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

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Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus

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Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers

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Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis

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MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells

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MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

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An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells

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The dystonia gene THAP1 controls DNA double-strand break repair choice

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The deubiquitinase TRABID stabilises the K29/K48-specific E3 ubiquitin ligase HECTD1

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Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction

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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

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Glial cell line‐derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia‐mediated glioma progression

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SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans

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The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells

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Proximity labeling in mammalian cells with TurboID and split-TurboID

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Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia

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Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

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Genome-wide Survey of Ribosome Collision

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Functional Assessment In Vivo of the Mouse Homologue of the Human Ala-9-Ser NHE6 Variant

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The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells | American Journal of Physiology-Endocrinology and Metabolism

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A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites

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The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation

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Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing

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A Septin Double Ring Controls the Spatiotemporal Organization of the ESCRT Machinery in Cytokinetic Abscission

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Molecular determinants in Frizzled, Reck, and Wnt7a for ligand-specific signaling in neurovascular development

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Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane

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Untitled document

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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.096
  
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  DOI: 10.1371/journal.pbio.2006094
  
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Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice

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  DOI: 10.1002/jnr.24397
  
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MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis

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  DOI: 10.1016/j.molcel.2018.09.031
  
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The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development

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Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

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Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

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actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com

LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons

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Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens

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EF24 (a curcumin analog) and ZSTK474 emphasizes the effect of cabozantinib in medullary thyroid cancer

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The Rheumatoid Arthritis-Associated Citrullinome

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Different Neuronal Activity Patterns Induce Different Gene Expression Programs

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