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Aug 2026
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ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway

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  DOI: 10.1016/j.isci.2026.117202
  
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sciencedirect.com/science/article/pii/S2589004226025800
Jun 2026
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Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer

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  DOI: 10.1016/j.celrep.2026.117559
  
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sciencedirect.com/science/article/pii/S2211124726006376
Dec 2025
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CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

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  DOI: 10.1038/s41523-025-00851-7
  
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nature.com/articles/s41523-025-00851-7
Aug 2025
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Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.str.2025.07.017
  
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1-s2.0-S2589004225015652-main-html.html

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  DOI: 10.1016/j.isci.2025.113304
  
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52.53.155.43/85cee3d161a0de2e88ed1ed9d4903a9813261aae/1-s2.0-S2589004225015652-main-html.html
Mar 2025
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CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.006
  
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sciencedirect.com/science/article/pii/S1535610825000583
Sep 2024
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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sciencedirect.com/science/article/pii/S1535610824003052
Jul 2024
www.cell.com www.cell.com

Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK

1
1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.07.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00254-3
Apr 2024
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The MYCN 5′ UTR as a therapeutic target in neuroblastoma

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1. scibot 25 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114134
  
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sciencedirect.com/science/article/pii/S2211124724004625
Feb 2024
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YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

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1. scibot 09 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109125
  
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52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
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The cyclimids: Degron-inspired cereblon binders for targeted protein degradation

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1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.chembiol.2024.01.003
  
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sciencedirect.com/science/article/pii/S2451945624000394
Dec 2023
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Heterogeneity and transcriptional drivers of triple-negative breast cancer

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113564
  
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sciencedirect.com/science/article/pii/S2211124723015760
Sep 2023
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Signaling-induced systematic repression of miRNAs uncovers cancer vulnerabilities and targeted therapy sensitivity

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.xcrm.2023.101200
  
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sciencedirect.com/science/article/pii/S2666379123003671
Aug 2023
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FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth

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  DOI: 10.1016/j.celrep.2023.112886
  
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sciencedirect.com/science/article/pii/S2211124723008975
Jun 2023
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BPS Publications

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1. scibot 01 Jun 2023
  
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  RRID:AB_2721897
  
  DOI: 10.1111/bph.16080
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
Aug 2022
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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.crmeth.2022.100271
  
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sciencedirect.com/science/article/pii/S2667237522001485
Mar 2022
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BPS Publications

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1. scibot 31 Mar 2022
  
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  RRID:AB_2721897
  
  DOI: 10.1111/bph.14558
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14558
Dec 2021
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KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

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1. scibot 18 Dec 2021
  
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  DOI: 10.1038/s41467-021-27502-2
  
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nature.com/articles/s41467-021-27502-2
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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

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1. scibot 17 Dec 2021
  
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  DOI: 10.7554/eLife.70691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
Nov 2021
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

1
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  DOI: 10.1016/j.celrep.2021.109934
  
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sciencedirect.com/science/article/pii/S2211124721014078
Sep 2021
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Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome

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sciencedirect.com/science/article/pii/S2211124721010354
Aug 2021
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Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9

1
1. scibot 31 Aug 2021
  
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  13331T
  
  DOI: 10.1016/j.crchbi.2021.100008
  
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52.53.155.43/660694af9c8e2ecacd48990031d316948592a872/1-s2.0-S2666246921000082-main-html.html
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Untitled document

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1. scibot 10 Aug 2021
  
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  DOI: 10.1111/bph.14558
  
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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

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  DOI: 10.1016/j.ccell.2018.10.014
  
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sciencedirect.com/science/article/pii/S153561081830480X
Jul 2021
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RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

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1. scibot 31 Jul 2021
  
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  CDK6
  
  DOI: 10.1186/s40659-019-0268-x
  
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link.springer.com/article/10.1186/s40659-019-0268-x
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Untitled document

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  DOI: 10.1016/j.ccell.2018.08.015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6179967/
Sep 2020
www.cell.com www.cell.com

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

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  DOI: 10.1016/j.ccell.2018.08.015
  
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cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
Jan 2020
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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.023
  
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  DOI: 10.1016/j.chembiol.2019.03.012
  
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sciencedirect.com/science/article/pii/S2451945619301084
Nov 2018
www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:

Untitled document

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Untitled document

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sciencedirect.com/science/article/pii/S1535610818303751