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Design, synthesis, and biological evaluation of pyranone–carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease

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  DOI: 10.1016/j.bioorg.2026.109887
  
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sciencedirect.com/science/article/pii/S0045206826004232
Mar 2026
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Radiation-induced autophagy regulates fibroblast mitochondrial metabolism and crosstalk with triple-negative breast cancer cells

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117096
  
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sciencedirect.com/science/article/pii/S2211124726001749
Jan 2026
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A positive feedback loop between FGR and p65 sustains satellite glial cell activation and chronic neuropathic pain

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116899
  
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sciencedirect.com/science/article/pii/S2211124725016717
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1-s2.0-S2589004225028019-main-html.html

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.isci.2025.114540
  
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54.241.53.176/270625103a88ccf8d45a0342ec37f8b03fae0d55/1-s2.0-S2589004225028019-main-html.html
Dec 2025
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A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

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1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.014
  
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sciencedirect.com:5037/science/article/pii/S0092867425013108
Oct 2025
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Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116487
  
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sciencedirect.com/science/article/pii/S2211124725012586
Jun 2025
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Cingulin is an RNA-binding protein promoting pancreatic cancer through enhancing importin 7-mediated phospho-ERK nuclear translocation

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115925
  
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sciencedirect.com/science/article/pii/S2211124725006965
May 2025
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A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.bioorg.2025.108551
  
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sciencedirect.com/science/article/pii/S0045206825004316
Apr 2025
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The splicing factor Acin1 is essential for embryonic development but has limited effects on muscle structure and homeostasis

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1. scibot 24 Apr 2025
  
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  DOI: 10.1038/s41598-025-98851-x
  
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link.springer.com/article/10.1038/s41598-025-98851-x
Feb 2025
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Generation of primordial germ cell-like cells by two germ plasm components, dnd1 and nanos3, in medaka (Oryzias latipes)

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111977
  
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sciencedirect.com/science/article/pii/S2589004225002378
Jan 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway

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1. scibot 17 Jan 2025
  
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  DOI: 10.1111/bph.17378
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17378
Dec 2024
www.cell.com www.cell.com

Nucleolar protein PEXF controls ribosomal RNA synthesis and pluripotency exit

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.12.004
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00726-3
Oct 2024
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Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice

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1. scibot 04 Oct 2024
  
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  AB_2722511
  
  DOI: 10.1016/j.lfs.2024.123085
  
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sciencedirect.com/science/article/pii/S0024320524006751
May 2024
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E3 ubiquitin ligase RNF2 protects polymerase ι from destabilization

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1. scibot 07 May 2024
  
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  Abcam, cat. no. ab150157
  
  DOI: 10.1016/j.bbamcr.2024.119743
  
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sciencedirect.com/science/article/pii/S0167488924000867
Jul 2023
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Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH

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1. scibot 07 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107201
  
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sciencedirect.com/science/article/pii/S2589004223012786
Apr 2023
www.biorxiv.org www.biorxiv.org

Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development

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1. scibot 20 Apr 2023
  
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  DOI: 10.1101/2023.04.05.535746
  
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biorxiv.org/content/10.1101/2023.04.05.535746v1
Mar 2023
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Sensitive magnetic particle imaging of haemoglobin degradation for the detection and monitoring of intraplaque haemorrhage in atherosclerosis

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.ebiom.2023.104509
  
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sciencedirect.com/science/article/pii/S2352396423000749
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 03 Mar 2023
  
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  RRID:AB_2722511
  
  DOI: 10.1111/bph.16025
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16025
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice

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1. scibot 03 Dec 2022
  
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  DOI: 10.3389/fphar.2022.1020670
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9714675/
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques

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1. scibot 21 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110864
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9080054/
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Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

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1. scibot 19 May 2022
  
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  DOI: 10.1016/j.molcel.2022.04.022
  
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sciencedirect.com/science/article/pii/S1097276522003859
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Chl1 coordinates with H3K9 methyltransferase Clr4 to reduce the accumulation of RNA-DNA hybrids and maintain genome stability

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1. scibot 13 May 2022
  
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  DOI: 10.1016/j.isci.2022.104313
  
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sciencedirect.com/science/article/pii/S2589004222005843
Aug 2021
www.immunohorizons.org www.immunohorizons.org

3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice

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1. scibot 16 Aug 2021
  
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  DOI: 10.4049/immunohorizons.2100028
  
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immunohorizons.org/content/5/6/523
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct skeletal stem cell types orchestrate long bone skeletogenesis

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1. scibot 23 Jul 2021
  
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  DOI: 10.7554/eLife.66063
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8289409/
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Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells

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1. scibot 02 Jul 2021
  
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  DOI: 10.1016/j.devcel.2021.06.011
  
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sciencedirect.com/science/article/pii/S1534580721005189
May 2021
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Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.stem.2021.04.009
  
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sciencedirect.com/science/article/pii/S1934590921001661
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.06.039
  
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pubmed.ncbi.nlm.nih.gov/32710848/
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Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.024
  
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sciencedirect.com/science/article/pii/S2211124720301856
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The Requirement for US28 During Cytomegalovirus Latency Is Independent of US27 and US29 Gene Expression

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1. scibot 08 Sep 2020
  
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  DOI: 10.3389/fcimb.2020.00186
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7198828/
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A Simplified and Effective Method for Generation of Experimental Murine Periodontitis Model

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1. scibot 06 Sep 2020
  
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  DOI: 10.3389/fbioe.2020.00444
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7261919/
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Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.01.013
  
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sciencedirect.com/science/article/pii/S1934590920300138
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Short‐term intermittent PTH 1–34 administration increased angiogenesis and matrix metalloproteinase‐9 in femora of mature and middle‐aged C57BL/6 Mice

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1. scibot 03 Sep 2020
  
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  RRID:AB_2722511
  
  DOI: 10.1113/EP087869
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/EP087869
Jan 2020
www.mdpi.com www.mdpi.com

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

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1. scibot 13 Jan 2020
  
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  DOI: 10.3390/ijms20184486
  
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mdpi.com/1422-0067/20/18/4486/htm