61 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation
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    1. scibot 18 Jul 2024
      AB_2722591

      DOI: 10.1016/j.isci.2024.110459

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    sciencedirect.com/science/article/pii/S2589004224016845
  3. May 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage
    1
    1. scibot 26 May 2024
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      DOI: 10.1016/j.isci.2024.109849

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    ncbi.nlm.nih.gov/pmc/articles/PMC11112614/
  5. Apr 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
    2
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114152

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    2. scibot 30 Apr 2024
      RRID:AB_2722591

      DOI: 10.1016/j.celrep.2024.114152

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    sciencedirect.com/science/article/pii/S2211124724004807
  7. www.sciencedirect.com www.sciencedirect.com
    Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway
    1
    1. scibot 25 Apr 2024
      15101S, Cell Signaling Technology

      DOI: 10.1016/j.jep.2024.118236

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    sciencedirect.com/science/article/pii/S037887412400535X
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.isci.2024.109649

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025009/
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    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
    2
    1. scibot 09 Apr 2024
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    2. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S221112472400398X
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis
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    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981016/
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment
    1
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.stem.2024.03.001

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    sciencedirect.com/science/article/pii/S1934590924000821
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
    1
    1. scibot 27 Mar 2024
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      DOI: 10.4103/1673-5374.389302

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
  14. link.springer.com link.springer.com
    The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target
    1
    1. scibot 26 Mar 2024
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      DOI: 10.1007/s00011-024-01863-y

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    link.springer.com/article/10.1007/s00011-024-01863-y
  15. link.springer.com link.springer.com
    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    1. scibot 20 Mar 2024
      RRID:AB_2722591

      DOI: 10.1007/s00210-024-03045-3

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    link.springer.com/article/10.1007/s00210-024-03045-3
  16. www.sciencedirect.com www.sciencedirect.com
    Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113967

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    sciencedirect.com/science/article/pii/S221112472400295X
  17. Feb 2024
  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
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      DOI: 10.1111/bph.16283

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  19. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
    1
    1. scibot 13 Feb 2024
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      DOI: 10.3390/cimb45120620

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    mdpi.com/1467-3045/45/12/620
  20. www.sciencedirect.com www.sciencedirect.com
    SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
    1
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113752

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    sciencedirect.com/science/article/pii/S2211124724000809
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of polyphenolic maqui (Aristotelia chilensis) extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn’s disease-like colitis
    1
    1. scibot 01 Feb 2024
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      DOI: 10.3389/fimmu.2023.1229767

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    ncbi.nlm.nih.gov/pmc/articles/PMC10811055/
  22. Dec 2023
  23. www.sciencedirect.com www.sciencedirect.com
    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
    2
    1. scibot 17 Dec 2023
      RRID:AB_2722591

      DOI: 10.1016/j.molcel.2023.11.015

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    2. scibot 17 Dec 2023
      RRID:AB_2722591

      DOI: 10.1016/j.molcel.2023.11.015

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    sciencedirect.com/science/article/pii/S1097276523009607
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113269

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    sciencedirect.com/science/article/pii/S2211124723012810
  26. Oct 2023
  27. www.sciencedirect.com www.sciencedirect.com
    HDL inhibits pancreatic acinar cell NLRP3 inflammasome activation and protect against acinar cell pyroptosis in acute pancreatitis
    1
    1. scibot 28 Oct 2023
      RRID:AB_2722591

      DOI: 10.1016/j.intimp.2023.110950

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    sciencedirect.com/science/article/pii/S1567576923012754
  28. Jul 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bexarotene improves motor function after spinal cord injury in mice
    1
    1. scibot 22 Jul 2023
      RRID:AB_2722591

      DOI: 10.4103/1673-5374.373676

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    ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
  30. www.sciencedirect.com www.sciencedirect.com
    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
    1
    1. scibot 22 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101129

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    sciencedirect.com/science/article/pii/S2666379123002574
  31. Jun 2023
  32. www.mdpi.com www.mdpi.com
    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
    1
    1. scibot 23 Jun 2023
      RRID:AB_2722591

      DOI: 10.3390/antiox12061303

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    mdpi.com/2076-3921/12/6/1303
  33. www.sciencedirect.com www.sciencedirect.com
    Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in severe patients with COVID-19
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      DOI: 10.1016/j.isci.2023.106929

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    sciencedirect.com/science/article/pii/S2589004223010064
  34. May 2023
  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation
    1
    1. scibot 05 May 2023
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      DOI: 10.1111/bph.16058

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16058
  36. Apr 2023
  37. www.sciencedirect.com www.sciencedirect.com
    The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome
    1
    1. scibot 06 Apr 2023
      RRID:AB_2722591

      DOI: 10.1016/j.immuni.2023.03.003

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    sciencedirect.com/science/article/pii/S1074761323001231
  38. Mar 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
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    1. scibot 28 Mar 2023
      RRID:AB_2722591

      DOI: 10.1016/j.immuni.2023.02.014

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    sciencedirect.com/science/article/pii/S1074761323000882
  40. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
    1. scibot 17 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  41. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation
    1
    1. scibot 04 Mar 2023
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      DOI: 10.1096/fj.202201469R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201469R
  42. Feb 2023
  43. link.springer.com link.springer.com
    Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6
    1
    1. scibot 02 Feb 2023
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      DOI: 10.1007/s12035-023-03232-y

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    link.springer.com/article/10.1007/s12035-023-03232-y
  44. Nov 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Commensal cow Roseburia reduces gut-dysbiosis-induced mastitis through inhibiting bacterial translocation by producing butyrate in mice
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      DOI: 10.1016/j.celrep.2022.111681

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    sciencedirect.com/science/article/pii/S2211124722015558
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 19 Nov 2022
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      DOI: 10.1111/bph.15949

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15949
  47. Oct 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
    1
    1. scibot 12 Oct 2022
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      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  49. Aug 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation
    1
    1. scibot 26 Aug 2022
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      DOI: 10.4103/1673-5374.346468

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    ncbi.nlm.nih.gov/pmc/articles/PMC9396521/
  51. www.sciencedirect.com www.sciencedirect.com
    Histone deacetylase-2 controls IL-1β production through the regulation of NLRP3 expression and activation in tuberculosis infection
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    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.isci.2022.104799

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    sciencedirect.com/science/article/pii/S2589004222010719
  52. www.sciencedirect.com www.sciencedirect.com
    Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
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    1. scibot 10 Aug 2022
      RRID:AB_2922902

      DOI: 10.1016/j.celrep.2022.111167

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    sciencedirect.com/science/article/pii/S2211124722009809
  53. Jun 2022
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Investigating the NLRP3 Inflammasome and its Regulator miR-223-3p in Multiple Sclerosis and Experimental Demyelination
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    1. scibot 17 Jun 2022
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      DOI: 10.1111/jnc.15650

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15650
  55. May 2022
  56. www.sciencedirect.com www.sciencedirect.com
    A TLR4-independent critical role for CD14 in intracellular LPS sensing
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      DOI: 10.1016/j.celrep.2022.110755

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  57. Apr 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control
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      RRID:AB_2722591

      DOI: 10.3389/fphar.2022.824138

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  59. Mar 2022
  60. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  61. Jan 2022
  62. link.springer.com link.springer.com
    miR-155 activates the NLRP3 inflammasome by regulating the MEK/ERK/NF-κB pathway in carotid atherosclerotic plaques in ApoE−/− mice
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      RRID:AB_2722591

      DOI: 10.1007/s13105-022-00871-y

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  63. www.sciencedirect.com www.sciencedirect.com
    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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      DOI: 10.1016/j.devcel.2021.12.020

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  64. www.sciencedirect.com www.sciencedirect.com
    Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis
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  65. Dec 2021
  66. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  67. Nov 2021
  68. www.nature.com www.nature.com
    Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
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      DOI: 10.1038/s41420-021-00716-5

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  69. Aug 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
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  71. www.sciencedirect.com www.sciencedirect.com
    Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity
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  72. Jun 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn’s disease by promoting intestinal inflammation
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  74. May 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection
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    Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
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      DOI: 10.1016/j.immuni.2020.04.010

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    sciencedirect.com/science/article/pii/S1074761320301680
  77. Dec 2020
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization
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      RRID:AB_2722591

      DOI: 10.7554/eLife.60194

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  79. Sep 2020
  80. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_2722591

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  81. www.sciencedirect.com www.sciencedirect.com
    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
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      DOI: 10.1016/j.cmet.2020.07.016

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      RRID:AB_2722591

      DOI: 10.1111/bph.15083

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  83. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_2722591

      DOI: 10.1111/bph.14998

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  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      AB_2722591

      DOI: 10.1111/bph.14938

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  85. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      AB_2722591

      DOI: 10.1111/bph.14806

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14806
  86. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_2722591

      DOI: 10.1111/bph.15026

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15026
  87. Nov 2018
  88. www.sciencedirect.com www.sciencedirect.com
    PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
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    sciencedirect.com/science/article/pii/S1534580718305975