30 Matching Annotations
  1. Feb 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
    1
    1. scibot 22 Feb 2024
      RRID:AB_2722613

      DOI: 10.1016/j.xcrm.2024.101434

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    sciencedirect.com/science/article/pii/S2666379124000570
  3. Nov 2023
  4. www.sciencedirect.com www.sciencedirect.com
    Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins
    1
    1. scibot 02 Nov 2023
      RRID:AB_2722613

      DOI: 10.1016/j.xcrm.2023.101255

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    sciencedirect.com/science/article/pii/S2666379123004329
  5. Oct 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
    1
    1. scibot 06 Oct 2023
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2023.112792

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    ncbi.nlm.nih.gov/pmc/articles/PMC10529362/
  7. Sep 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KMT2C expression and DNA homologous recombination repair factors in lung cancers with a high-grade fetal adenocarcinoma component
    1
    1. scibot 09 Sep 2023
      RRID:AB_2722613

      DOI: 10.21037/tlcr-23-137

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    ncbi.nlm.nih.gov/pmc/articles/PMC10483084/
  9. Aug 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes
    1
    1. scibot 19 Aug 2023
      RRID:AB_2722613

      DOI: 10.1158/1078-0432.CCR-22-3156

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425726/
  11. Jul 2023
  12. 52.53.155.43 52.53.155.43
    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
    1
    1. scibot 18 Jul 2023
      RRID:AB_2722613

      DOI: 10.15252/embr.202256437

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    52.53.155.43/82562d81b2014f2e2d5c134f5e9ab42cec01f29a/embr.202256437-html.html
  13. May 2023
  14. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
    1
    1. scibot 10 May 2023
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2023.112484

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    sciencedirect.com/science/article/pii/S2211124723004953
  15. Apr 2023
  16. www.sciencedirect.com www.sciencedirect.com
    A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
    1
    1. scibot 29 Apr 2023
      RRID:AB_2722613

      DOI: 10.1016/j.ccell.2023.04.002

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    sciencedirect.com/science/article/pii/S1535610823001289
  17. Feb 2023
  18. www.embopress.org www.embopress.org
    Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma
    1
    1. scibot 15 Feb 2023
      RRID:AB_2722613

      DOI: 10.15252/emmm.202216863

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    embopress.org/doi/10.15252/emmm.202216863
  19. Jan 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Elevated PAF1-RAD52 axis confers chemoresistance to human cancers
    1
    1. scibot 31 Jan 2023
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2023.112043

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    sciencedirect.com/science/article/pii/S2211124723000542
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
    1
    1. scibot 28 Jan 2023
      RRID:AB_2722613

      DOI: 10.1158/1078-0432.CCR-22-2551

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    ncbi.nlm.nih.gov/pmc/articles/PMC9873249/
  22. Oct 2022
  23. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
    1
    1. scibot 20 Oct 2022
      RRID:AB_272261

      DOI: 10.1016/j.molcel.2022.09.025

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @a5munoz

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      RRID:AB_2722613 RRIDCUR:Unresolved
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    sciencedirect.com/science/article/pii/S1097276522009352
  24. Jun 2022
  25. 52.53.155.43 52.53.155.43
    mct-21-0798-html.html
    2
    1. scibot 30 Jun 2022
      RRID:AB_2722613

      DOI: 10.1158/1535-7163.mct-21-0798

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    2. scibot 24 Jun 2022
      RRID:AB_2722613

      DOI: 10.1158/1535-7163.MCT-21-0798

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

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    52.53.155.43/9002f710d59c7dcb5dd8d70237b19dc81be5139d/mct-21-0798 (1)-html.html
  26. May 2022
  27. www.sciencedirect.com www.sciencedirect.com
    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
    1
    1. scibot 25 May 2022
      RRID:AB_2722613

      DOI: 10.1016/j.molcel.2022.04.031

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

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    sciencedirect.com/science/article/pii/S109727652200394X
  28. www.sciencedirect.com www.sciencedirect.com
    SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine
    1
    1. scibot 12 May 2022
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2022.110813

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

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    sciencedirect.com/science/article/pii/S2211124722005848
  29. Apr 2022
  30. www.nature.com www.nature.com
    Genetic instability from a single S phase after whole-genome duplication
    1
    1. scibot 08 Apr 2022
      RRID:AB_2722613

      DOI: 10.1038/s41586-022-04578-4

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

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    nature.com/articles/s41586-022-04578-4
  31. Mar 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
    1
    1. scibot 02 Mar 2022
      RRID:AB_2722613

      DOI: 10.1016/j.molcel.2022.01.020

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1097276522000855
  33. Dec 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining
    1
    1. scibot 17 Dec 2021
      RRID:AB_2722613

      DOI: 10.1158/0008-5472.CAN-20-2960

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8260463/
  35. Sep 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
    1
    1. scibot 23 Sep 2021
      RRID:AB_2722613

      DOI: 10.1016/j.molcel.2021.09.005

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S1097276521007395
  37. Jul 2021
  38. www.sciencedirect.com www.sciencedirect.com
    MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer
    1
    1. scibot 31 Jul 2021
      RRID:AB_2722613

      DOI: 10.1016/j.ebiom.2019.03.027

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @ethanbadger

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2352396419301677
  39. Mar 2021
  40. www.sciencedirect.com www.sciencedirect.com
    A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
    1
    1. scibot 04 Mar 2021
      RRID:AB_2722613

      DOI: 10.1016/j.chembiol.2021.02.006

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2722613
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    sciencedirect.com/science/article/pii/S2451945621000581
  41. Jan 2021
  42. link.springer.com link.springer.com
    Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
    1
    1. scibot 12 Jan 2021
      RRID:AB_2722613

      DOI: 10.1186/s13046-020-01811-8

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @Naa003

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      RRID:AB_2722613 RRIDCUR:Validated
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    link.springer.com/article/10.1186/s13046-020-01811-8
  43. Nov 2020
  44. www.sciencedirect.com www.sciencedirect.com
    PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage
    1
    1. scibot 07 Nov 2020
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2020.108347

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @Naa003

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112472031336X
  45. Oct 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
    1
    1. scibot 24 Oct 2020
      RRID:AB_2722613

      DOI: 10.7554/eLife.61287

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @evieth

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      RRID:AB_2722613 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7553775/
  47. Sep 2020
  48. www.sciencedirect.com www.sciencedirect.com
    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
    1
    1. scibot 13 Sep 2020
      RRID:AB_2722613

      DOI: 10.1016/j.molcel.2020.06.017

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2722613
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    sciencedirect.com/science/article/pii/S1097276520304020
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
    1
    1. scibot 13 Jan 2020
      RRID:AB_2722613

      DOI: 10.1016/j.molcel.2019.06.023

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @ethanbadger

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519304794
  51. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2722613

      DOI: 10.1016/j.celrep.2019.01.083

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @ethanbadger

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719301123
  52. www.sciencedirect.com www.sciencedirect.com
    MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer
    1
    1. scibot 12 Jan 2020
      RRID:AB_2722613

      DOI: 10.1016/j.ebiom.2019.03.027

      Resource: (Abcam Cat# ab133534, RRID:AB_2722613)

      Curator: @ethanbadger

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2352396419301677
  53. Nov 2018
  54. www.sciencedirect.com www.sciencedirect.com
    Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
    1
    1. scibot 05 Nov 2018
      RRID:AB_2722613

      Curator: @Jmenke

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      (Abcam Cat# ab133534, RRID:AB_2722613)

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      RRID:AB_2722613 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418311176