88 Matching Annotations
  1. Jul 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
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    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114448

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    sciencedirect.com/science/article/pii/S2211124724007770
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    Metformin ameliorates neuroinflammatory environment for neurons and astrocytes during in vitro and in vivo stroke and tobacco smoke chemical exposure: Role of Nrf2 activation
    1
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      DOI: 10.1016/j.redox.2024.103266

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    sciencedirect.com/science/article/pii/S2213231724002441
  4. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
    1
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      DOI: 10.1016/j.crmeth.2024.100814

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    cell.com/cell-reports-methods/abstract/S2667-2375(24)00179-6
  5. www.sciencedirect.com www.sciencedirect.com
    Membrane HIV-1 Envelope Glycoproteins Stabilized More Strongly in a Pretriggered Conformation than Natural Virus Envs
    1
    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.isci.2024.110141

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    sciencedirect.com/science/article/pii/S258900422401366X
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.042

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    sciencedirect.com/science/article/pii/S0092867424004689
  8. www.sciencedirect.com www.sciencedirect.com
    Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates
    2
    1. scibot 30 May 2024
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      DOI: 10.1016/j.chembiol.2024.05.001

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      DOI: 10.1016/j.chembiol.2024.05.001

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    sciencedirect.com/science/article/pii/S2451945624001806
  9. www.sciencedirect.com www.sciencedirect.com
    On the covalent nature of lysine polyphosphorylation
    1
    1. scibot 07 May 2024
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      DOI: 10.1016/j.molcel.2024.03.029

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    sciencedirect.com/science/article/pii/S1097276524002788
  10. Apr 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1126/sciadv.adk4423

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    ncbi.nlm.nih.gov/pmc/articles/PMC10971413/
  12. Mar 2024
  13. www.sciencedirect.com www.sciencedirect.com
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
    2
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113975

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    2. scibot 22 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113975

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    sciencedirect.com/science/article/pii/S2211124724003036
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dynamic ubiquitination balance of cell proliferation and endoreduplication regulators determines plant organ size
    1
    1. scibot 17 Mar 2024
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      DOI: 10.1126/sciadv.adj2570

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    ncbi.nlm.nih.gov/pmc/articles/PMC10936951/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caldendrin is a repressor of PIEZO2 channels and touch sensation in mice
    1
    1. scibot 13 Mar 2024
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      DOI: 10.1523/JNEUROSCI.1402-23.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10919251/
  16. www.sciencedirect.com www.sciencedirect.com
    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
    2
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      DOI: 10.1016/j.isci.2024.109188

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    2. scibot 06 Mar 2024
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      DOI: 10.1016/j.isci.2024.109188

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    sciencedirect.com/science/article/pii/S2589004224004097
  17. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 targets ribosomal RNA biogenesis
    2
    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113891

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      DOI: 10.1016/j.celrep.2024.113891

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    sciencedirect.com/science/article/pii/S2211124724002195
  18. 52.53.155.43 52.53.155.43
    JNEUROSCI.1402-23.2023.full-html.html
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    52.53.155.43/c6735ea00caadbe2362f054bb10b7d7820874700/JNEUROSCI.1402-23.2023.full-html.html
  19. Feb 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Aberrant cortex contractions impact mammalian oocyte quality
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.027

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    sciencedirect.com/science/article/pii/S1534580724000479
  21. www.biorxiv.org www.biorxiv.org
    UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1101/2024.02.13.580169

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    biorxiv.org/content/10.1101/2024.02.13.580169v1
  22. 52.53.155.43 52.53.155.43
    JNEUROSCI.1402-23.2023.full-html.html
    1
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    52.53.155.43/c6735ea00caadbe2362f054bb10b7d7820874700/JNEUROSCI.1402-23.2023.full-html.html
  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Feb 2024
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      DOI: 10.1111/bph.16294

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16294
  24. Jan 2024
  25. 52.53.155.43 52.53.155.43
    JNEUROSCI.1402-23.2023.full-html.html
    1
    1. scibot 26 Jan 2024
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    52.53.155.43/c6735ea00caadbe2362f054bb10b7d7820874700/JNEUROSCI.1402-23.2023.full-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1158/1078-0432.CCR-23-0964

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    ncbi.nlm.nih.gov/pmc/articles/PMC10767302/
  27. Sep 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function
    1
    1. scibot 09 Sep 2023
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      DOI: 10.3389/fphar.2023.1227145

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    ncbi.nlm.nih.gov/pmc/articles/PMC10484598/
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Sublethal necroptosis signaling promotes inflammation and liver cancer
    1
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      DOI: 10.1016/j.immuni.2023.05.017

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    sciencedirect.com/science/article/pii/S1074761323002340
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.scr.2023.103108

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    sciencedirect.com/science/article/pii/S1873506123000946
  33. link.springer.com link.springer.com
    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
    1
    1. scibot 02 May 2023
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      DOI: 10.1186/s12974-023-02784-z

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    link.springer.com/article/10.1186/s12974-023-02784-z
  34. Apr 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.molcel.2023.03.027

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    sciencedirect.com/science/article/pii/S109727652300240X
  36. www.sciencedirect.com www.sciencedirect.com
    Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.scr.2023.103105

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    sciencedirect.com/science/article/pii/S1873506123000910
  37. journals.biologists.com journals.biologists.com
    A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1242/dev.201035

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    journals.biologists.com/dev/article/150/6/dev201035/297263/A-proinsulin-dependent-interaction-between-ENPL-1
  38. Mar 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age
    1
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      DOI: 10.1186/s12987-023-00416-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC9999561/
  40. Feb 2023
  41. www.sciencedirect.com www.sciencedirect.com
    A complete allosteric map of a GTPase switch in its native cellular network
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      DOI: 10.1016/j.cels.2023.01.003

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    sciencedirect.com/science/article/pii/S2405471223000297
  42. Oct 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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      DOI: 10.7554/eLife.80014

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    ncbi.nlm.nih.gov/pmc/articles/PMC9592085/
  44. Sep 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Protocol to use RNaseH1-based CRISPR to modulate locus-associated R-loops
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      DOI: 10.1016/j.xpro.2022.101734

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    sciencedirect.com/science/article/pii/S2666166722006141
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
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      DOI: 10.1016/j.isci.2022.105011

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474293/
  47. www.sciencedirect.com www.sciencedirect.com
    RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss
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      DOI: 10.1016/j.devcel.2022.08.011

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    sciencedirect.com/science/article/pii/S1534580722005974
  48. www.nature.com www.nature.com
    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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      DOI: 10.1038/s42003-022-03917-5

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    nature.com/articles/s42003-022-03917-5
  49. link.springer.com link.springer.com
    Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
    1
    1. scibot 10 Sep 2022
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      DOI: 10.1186/s12987-022-00371-7

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    link.springer.com/article/10.1186/s12987-022-00371-7
  50. Jun 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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      DOI: 10.1016/j.isci.2022.104518

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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  52. www.sciencedirect.com www.sciencedirect.com
    Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529
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      DOI: 10.1016/j.celrep.2022.110924

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    Coenzyme A precursors flow from mother to zygote and from microbiome to host
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  54. May 2022
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    Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus
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      DOI: 10.1007/s12031-022-02030-w

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    Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events
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  57. Mar 2022
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    Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor
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  59. Dec 2021
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    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
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  61. Nov 2021
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    Functional differences among the spike glycoproteins of multiple emerging severe acute respiratory syndrome coronavirus 2 variants of concern
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c
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    Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors
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  66. Sep 2021
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    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
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  68. Aug 2021
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    CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
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    Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis
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  71. May 2021
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    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
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    Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation
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  74. Apr 2021
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    Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity
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    Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation
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    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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    An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation
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  79. Feb 2021
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    Functional impact of a congenital stationary night blindness type 2 mutation depends on subunit composition of Cav1.4 Ca2+ channels
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      anti-rabbit HRP

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    A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking
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    Prenatal Electronic Cigarette Exposure Decreases Brain Glucose Utilization & Worsens Outcome in Offspring Hypoxic‐ischemic Brain Injury
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    Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype
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    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
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  85. Jan 2021
  86. elifesciences.org elifesciences.org
    chTOG is a conserved mitotic error correction factor
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  87. Dec 2020
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    An RNA Repair Operon Regulated by Damaged tRNAs
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  89. Nov 2020
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    CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion
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    Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination
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  92. Oct 2020
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    Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury
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  94. Sep 2020
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    OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
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    FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster
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    UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2
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    The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
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    Loss of Piccolo function in rats induces cerebellar network dysfunction and Pontocerebellar Hypoplasia type 3-like phenotypes
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      HRP-conjugated secondary antibodies

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    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination
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  101. Jan 2020
  102. academic.oup.com academic.oup.com
    Calcifediol decreases interleukin-6 secretion by cultured human trophoblasts from GDM pregnancies
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  103. www.eneuro.org www.eneuro.org
    Removal of the potassium chloride co-transporter from the somatodendritic membrane of axotomized motoneurons is independent of BDNF/TrkB signaling but is controlled by neuromuscular innervation
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    Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21
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    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
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      DOI: 10.1016/j.chembiol.2019.06.003

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      DOI: 10.1016/j.immuni.2019.03.014

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    Complement C4 Prevents Viral Infection through Capsid Inactivation
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
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      DOI: 10.1016/j.ccell.2018.10.004

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    IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration
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      DOI: 10.1016/j.celrep.2019.02.013

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  110. Nov 2018
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    GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing
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    A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster
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    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
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    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
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