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aacrjournals.org aacrjournals.org

Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0488
  
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aacrjournals.org/cancerimmunolres/article/13/12/2054/768330/Functional-Genetic-Screens-Reveal-Key-Pathways
54.241.53.176 54.241.53.176

cd-25-1907-html.html

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2159-8290.CD-25-1907
  
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54.241.53.176/c343cff9cf99b6aff211bdef582679d3b0f1da71/cd-25-1907-html.html
Apr 2026
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Engineered oncolytic virus armed with anti-PCSK9 scFv boosts long-term CD8+ T cell immunity via rewiring MHC-I antigen presentation

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.xcrm.2026.102724
  
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sciencedirect.com/science/article/pii/S2666379126001412
Feb 2026
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Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.cell.2026.01.001
  
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sciencedirect.com/science/article/pii/S0092867426000486
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Preclinical State of Graves' Ophthalmopathy Characterized by Hypoxia of T-cells Identified via Multiomics Analysis

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1. scibot 20 Nov 2025
  
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  DOI: 10.1210/clinem/dgaf230
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12623031/
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Trilaciclib triggers a neutrophil-related immune response and sensitizes non-small cell lung cancer to anti-PD-1 therapy

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1. scibot 06 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102434
  
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sciencedirect.com/science/article/pii/S2666379125005075
Aug 2025
rupress.org rupress.org

Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity

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1. scibot 27 Aug 2025
  
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  DOI: 10.1084/jem.20242360
  
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rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.012
  
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sciencedirect.com/science/article/pii/S1535610825003186
May 2025
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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cmet.2025.04.008
  
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sciencedirect.com/science/article/pii/S1550413125002189
Apr 2025
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Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.devcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1534580725001558
Mar 2025
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.007
  
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sciencedirect.com/science/article/pii/S107476132500072X
Feb 2025
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101975
  
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sciencedirect.com/science/article/pii/S2666379125000485
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor–Ligand Interactions That Instructs Intratumoral γδT-cell Activity

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1. scibot 25 Jan 2025
  
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  AB_2728381
  
  DOI: 10.1158/0008-5472.CAN-24-1509
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11733534/
Dec 2024
www.cell.com www.cell.com

Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

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1. scibot 29 Dec 2024
  
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  RRID:AB_2728381
  
  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
Sep 2024
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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1. scibot 25 Sep 2024
  
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  AB_2728381
  
  DOI: 10.1016/j.xcrm.2024.101718
  
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sciencedirect.com/science/article/pii/S2666379124004397
Apr 2024
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QDPR deficiency drives immune suppression in pancreatic cancer

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1. scibot 23 Apr 2024
  
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  DOI: 10.1016/j.cmet.2024.03.015
  
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sciencedirect.com/science/article/pii/S1550413124001190
Mar 2024
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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.114003
  
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sciencedirect.com/science/article/pii/S2211124724003310
Jun 2023
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Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates

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1. scibot 23 Jun 2023
  
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  RRID:AB_2728381
  
  DOI: 10.1016/j.immuni.2023.05.005
  
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sciencedirect.com/science/article/pii/S1074761323002224
Apr 2023
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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.019
  
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sciencedirect.com/science/article/pii/S1535610823000922
Feb 2023
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Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.031
  
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sciencedirect.com/science/article/pii/S1074761323000432
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OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.xcrm.2023.100939
  
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sciencedirect.com/science/article/pii/S2666379123000319
Dec 2022
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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.cmet.2022.11.003
  
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sciencedirect.com/science/article/pii/S1550413122004946
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of CDK4/6 promotes CD8 T cell memory formation

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1. scibot 02 Apr 2022
  
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  DOI: 10.1158/2159-8290.CD-20-1540
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8487897/
Jan 2022
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Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19

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1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110235
  
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sciencedirect.com/science/article/pii/S2211124721017447