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Protocol for assessing molecular signatures and metabolic function of primary murine cortical astrocytes

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pmc.ncbi.nlm.nih.gov/articles/PMC13506315/
Aug 2026
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Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis

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sciencedirect.com/science/article/pii/S2211124726009071
Jul 2026
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Synthetic multicolor antigen-stabilizable nanobody platform for intersectional labelling and functional imaging

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PRKCI-ECT2 copy number gain promotes developmental reprogramming and metastatic competence in lung adenocarcinoma

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Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis

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sciencedirect.com/science/article/pii/S1934590926002286
Jun 2026
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SLC22A3/OCT3 drives serotonin-mediated stemness in pancreatic cancer

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May 2026
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Mapping AAV capsid sequences to functions through function-guided in silico evolution

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Apr 2026
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Molecular markers of Rathke’s cleft cysts and their clinical correlates: insights from experimental and human analyses

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thejns.org/view/journals/j-neurosurg/aop/article-10.3171-2025.12.JNS251835/article-10.3171-2025.12.JNS251835.xml
Mar 2026
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AAVs targeting human carbonic anhydrase IV enhance gene delivery to the brain

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pmc.ncbi.nlm.nih.gov/articles/PMC12942408/
Feb 2026
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Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis

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Jan 2026
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dev204631-html.html

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  DOI: 10.1242/dev.204631
  
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54.241.53.176/40ddadd450006a821c5ee4f741165bb1c49f5954/dev204631-html.html
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Human liver cholangiocyte organoids capture the heterogeneity of in vivo liver ductal epithelium

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  DOI: 10.1016/j.celrep.2025.116786
  
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Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry

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  DOI: 10.1016/j.neuron.2025.11.009
  
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Dec 2025
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Cranial neural crest shortage leads to extensive craniofacial anomalies in mice mutant for the NR2F1/2 nuclear receptors

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  DOI: 10.1016/j.ydbio.2025.11.011
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12720995/
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Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung

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sciencedirect.com:5037/science/article/pii/S2211124725015220
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Bioengineering mini-colons for ex vivo colorectal cancer research

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  DOI: 10.1038/s41596-025-01292-z
  
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nature.com/articles/s41596-025-01292-z
Nov 2025
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The antiviral Interferon pathway drives astrocyte aging and motor decline

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  DOI: 10.1101/2025.11.12.688147
  
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biorxiv.org/content/10.1101/2025.11.12.688147v1
Oct 2025
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BST2 expression at astrocyte borders promotes microglial recruitment via the C3/C3aR signaling

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  DOI: 10.1016/j.neuron.2025.09.038
  
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Sep 2025
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Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome

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Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling

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Aug 2025
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1-s2.0-S2589004225015962-main-html.html

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Chemical reprogramming of human blood cells to pluripotent stem cells

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cell.com/cell-stem-cell/abstract/S1934-5909(25)00260-7
Jul 2025
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Distribution and morphological features of astrocytes and Purkinje cells in the human cerebellum

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1. scibot 22 Jul 2025
  
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  DOI: 10.3389/fnana.2025.1592671
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12271190/
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CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma

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  DOI: 10.1016/j.xcrm.2025.102208
  
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Jun 2025
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M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury

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  DOI: 10.4103/1673-5374.324858
  
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journals.lww.com/nrronline/fulltext/2022/05000/m1_type_microglia_can_induce_astrocytes_to_deposit.34.aspx
pubs.acs.org pubs.acs.org

HIF-1α Stabilization Hampers the Chondrogenic Differentiation of Aged Bone Marrow Mesenchymal Stem Cells by Adenosine A2A/A2B Receptors Imbalance

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  DOI: 10.1021/acsptsci.5c00190
  
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pubs.acs.org/doi/full/10.1021/acsptsci.5c00190
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Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis

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  DOI: 10.1186/s13024-025-00864-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12181884/
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Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity

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  DOI: 10.1016/j.celrep.2025.115809
  
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cell.com/cell-reports/abstract/S2211-1247(25)00580-7
May 2025
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Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1

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  DOI: 10.1158/0008-5472.CAN-24-1388
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11534540/
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Inflammasome signaling in astrocytes modulates hippocampal plasticity

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  DOI: 10.1016/j.immuni.2025.04.007
  
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sciencedirect.com/science/article/pii/S1074761325001700
Feb 2025
52.53.155.43 52.53.155.43

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis

1
1. scibot 06 Feb 2025
  
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  DOI: 10.1101/2024.09.09.611621
  
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52.53.155.43/ccdd8f2b9b0076ccdaf42c273b248e5adbb5da1d/2024.09.09.611621v1.full-html.html
Dec 2024
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Generation of self-organized neuromusculoskeletal tri-tissue organoids from human pluripotent stem cells

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.11.005
  
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sciencedirect.com/science/article/pii/S1934590924004041
Nov 2024
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Generation of self-renewing neuromesodermal progenitors with neuronal and skeletal muscle bipotential from human embryonic stem cells

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.crmeth.2024.100897
  
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Oct 2024
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A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.stem.2024.09.001
  
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sciencedirect.com/science/article/pii/S1934590924003151
Sep 2024
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.012
  
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Decoding the pathogenesis of spermatogenic failure in cryptorchidism through single-cell transcriptomic profiling

1
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Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration

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Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer

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Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids

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SOX2 and SOX9 Expression in Developing Postnatal Opossum (Monodelphis domestica) Cortex

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A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs

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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

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Nov 2023
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Mechanical overloading leads to chondrocyte degeneration and senescence via Zmpste24 mediated nuclear membrane instability

2
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Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren’s syndrome

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Sep 2023
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Protocol for the purification and transcriptomic analysis of mouse astrocytes using GFAT

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Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

1
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Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

1
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Rat post-implantation epiblast-derived pluripotent stem cells produce functional germ cells

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Aug 2023
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Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity

1
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Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice

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Bioengineered human tissue regeneration and repair using endogenous stem cells

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Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

1
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MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice

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Jun 2023
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Photobiomodulation inhibits the expression of chondroitin... : Neural Regeneration Research

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Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells

1
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Ex utero monkey embryogenesis from blastocyst to early organogenesis

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Hic1 identifies a specialized mesenchymal progenitor population in the embryonic limb responsible for bone superstructure formation

1
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Mar 2023
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Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer

1
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Feb 2023
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Lymphatic vessels in bone support regeneration after injury

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Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET

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ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance

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Dec 2022
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Single-cell RNA sequencing uncovers dynamic roadmap and cell-cell communication during buffalo spermatogenesis

1
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Nov 2022
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Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair

1
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Transcription factor Hb9 is expressed in glial cell lineages in the developing mouse spinal cord

1
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eneuro.org/content/9/6/ENEURO.0214-22.2022
Oct 2022
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KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice

1
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Jul 2022
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can-21-3713-html.html

1
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MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

1
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  DOI: 10.1186/s12974-022-02548-1
  
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Lymphatics act as a signaling hub to regulate intestinal stem cell activity

1
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May 2022
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Single-cell analysis of human testis aging and correlation with elevated body mass index

1
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  DOI: 10.1016/j.devcel.2022.04.004
  
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Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease

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Stem cell differentiation with consistent lineage commitment induced by a flash of ultrafast-laser activation in vitro and in vivo

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Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease

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SDF-1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up-regulating FoxO1 via binding to CXCR4

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Renal Subcapsular Delivery of PGE2 Promotes Kidney Repair by Activating Endogenous Sox9+ Stem Cells

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Activity-dependent modulation of synapse-regulating genes in astrocytes

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Generation and differentiation of chemically derived hepatic progenitors from mouse primary hepatocytes

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Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

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Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

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Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis

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Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease

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Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

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Smooth Muscle Cell Reprogramming in Aortic Aneurysms

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The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty

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Untitled document

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Nov 2018
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Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes

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