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Sep 2026
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Aging microenvironment induces CD8+ T cell exhaustion by suppressing hepatic β-hydroxybutyrylate synthesis

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sciencedirect.com/science/article/pii/S1550413126003347
Jul 2026
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A Circulating GPNMB-Based Multimodal Model Integrates Tumor-Immune Crosstalk to Predict Immunotherapy Response in Esophageal Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC13320204/
May 2026
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Cross-tissue atlas of mucosa-associated lymphoid tissue lymphomas reveals intratumoral heterogeneity and microenvironmental subtypes

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sciencedirect.com/science/article/pii/S2666379126002028
Apr 2026
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cd-25-1907-html.html

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54.241.53.176/c343cff9cf99b6aff211bdef582679d3b0f1da71/cd-25-1907-html.html
Feb 2026
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Modulating the tumor immune phenotypes by radiotherapy: formulating and validating the combination therapy of radiation, PD-L1, and TIM-3 blockade in colorectal cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12933762/
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TNF-⍺-mediated myeloid-instructed CD14+CD4+ T cells are associated with poor survival in lung adenocarcinoma

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sciencedirect.com/science/article/pii/S2666379126000108
Dec 2025
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Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade

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Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12667737/
Nov 2025
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Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12603150/
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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sciencedirect.com/science/article/pii/S2211124725012975
Oct 2025
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Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan

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pmc.ncbi.nlm.nih.gov/articles/PMC12539258/
Aug 2025
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Depletion of Effector Regulatory T Cells Associates with Major Response to Induction Dual Immune Checkpoint Blockade

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pmc.ncbi.nlm.nih.gov/articles/PMC12319410/
Jun 2025
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Bile acids activate cancer-associated fibroblasts and induce an immunosuppressive microenvironment in cholangiocarcinoma

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sciencedirect.com/science/article/pii/S1535610825002260
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Statistical modeling and analysis of cell counts from multiplexed imaging data

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cell.com/cell-systems/abstract/S2405-4712(25)00129-2
May 2025
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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

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sciencedirect.com/science/article/pii/S1550413125002189
Dec 2024
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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis

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pmc.ncbi.nlm.nih.gov/articles/PMC11666332/
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Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders

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sciencedirect.com/science/article/pii/S2666379124006220
Nov 2024
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Langerhans cells directly interact with resident T cells in the human epidermis

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.xjidi.2024.100324
  
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sciencedirect.com/science/article/pii/S2667026724000729
Jul 2024
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Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

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May 2024
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Decision model for durable clinical benefit from front- or late-line immunotherapy alone or with chemotherapy in non-small cell lung cancer

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sciencedirect.com/science/article/pii/S2666634024002046
Apr 2024
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Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

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Feb 2024
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UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

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Jan 2024
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Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

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Nov 2023
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Multi-omics indicators of long-term survival benefits after immune checkpoint inhibitor therapy

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Jun 2023
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Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2

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Spatially resolved multi-omics single-cell analyses inform mechanisms of immune-dysfunction in pancreatic cancer

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52.53.155.43/71ccfaec92c7763faf07cdf10a5de07b1aba97a1/1-s2.0-S0016508523008107-main-html.html
May 2023
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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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  DOI: 10.1038/s41467-023-38605-3
  
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nature.com/articles/s41467-023-38605-3
Nov 2022
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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

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sciencedirect.com/science/article/pii/S1535610822005128
Oct 2021
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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

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  DOI: 10.1016/j.xcrm.2021.100419
  
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sciencedirect.com/science/article/pii/S2666379121002810
Jul 2021
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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

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  DOI: 10.1016/j.immuni.2021.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8188302/
Feb 2021
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Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Jan 2020
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Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

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  DOI: 10.1016/j.celrep.2019.05.041
  
  Resource: (Cell Signaling Technology Cat# 86163, RRID:AB_2728833)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2728833
  
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  RRID:AB_2728833 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2728833

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scibot

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pubmed.ncbi.nlm.nih.gov/31189114/
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1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_2728833
  
  DOI: 10.1016/j.cell.2019.03.005
  
  Resource: (Cell Signaling Technology Cat# 86163, RRID:AB_2728833)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2728833
  
  What is this?
  
  RRID:AB_2728833 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2728833

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419302673