22 Matching Annotations
  1. Last 7 days
  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70602
  3. May 2026
  4. www.science.org www.science.org
    GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
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    science.org/doi/10.1126/sciadv.adv1434
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    14-3-3 phosphorylation inhibits 14-3-3θ’s ability to regulate LRRK2 kinase activity and toxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11578116/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12397289/
  8. 52.53.155.43 52.53.155.43
    2025.08.28.672006v1.full-html.html
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    52.53.155.43/1c78deaa12ef1065bee04217bb87fcbf90d61c87/2025.08.28.672006v1.full-html.html
  9. Jul 2025
  10. www.science.org www.science.org
    Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2
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    science.org/doi/10.1126/sciadv.adt2050
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462683/
  12. Jun 2025
  13. www.science.org www.science.org
    Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2
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    science.org/doi/10.1126/sciadv.adt2050
  14. Mar 2025
  15. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/c83c3399f0f3ceedbbadf4465eff5f081b0ef0bc/PDF-html.html
  16. Jan 2025
  17. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/04879393ca39922a7c00ba26ca5d51a54504677a/PDF-html.html
  18. Sep 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11565912/
  20. Dec 2023
  21. elifesciences.org elifesciences.org
    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
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    elifesciences.org/articles/87255
  22. Jun 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
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    sciencedirect.com/science/article/pii/S2589004222007477
  24. Nov 2021
  25. link.springer.com link.springer.com
    Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein
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    link.springer.com/article/10.1186/s40478-021-01283-7
  26. Oct 2021
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8461695/
  28. Aug 2021
  29. link.springer.com link.springer.com
    Untitled document
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    link.springer.com/article/10.1186/s40478-019-0679-5
  30. Jul 2021
  31. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Untitled document
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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0679-5
  32. Sep 2020
  33. www.sciencedirect.com www.sciencedirect.com
    The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network
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    sciencedirect.com/science/article/pii/S2211124720305635
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications
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    ncbi.nlm.nih.gov/pmc/articles/PMC6978918/
  35. Jan 2020
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LRRK2 phosphorylation on synapsin I regulates glutamate release at presynaptic sites
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14778
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6391792/
  38. Nov 2018
  39. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons
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    actaneurocomms.biomedcentral.com/articles/10.1186/s40478-018-0550-0