32 Matching Annotations
  1. Oct 2024
  2. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson’s disease
    1
    1. scibot 02 Oct 2024
      AB_2732849

      DOI: 10.1186/s12974-024-03234-0

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    jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-024-03234-0
  3. Aug 2024
  4. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
    1
    1. scibot 02 Aug 2024
      C1q

      DOI: 10.1186/s13024-021-00440-9

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    molecularneurodegeneration.biomedcentral.com/article/10.1186/s13024-021-00440-9
  5. Jul 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.cell.2024.05.058

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    sciencedirect.com/science/article/pii/S0092867424006391
  7. www.biorxiv.org www.biorxiv.org
    CD11c-expressing microglia are transient, driven by interactions with apoptotic cells
    1
    1. scibot 04 Jul 2024
      RRID:AB_2732849

      DOI: 10.1101/2024.06.24.600082

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    biorxiv.org/content/10.1101/2024.06.24.600082v2
  8. Apr 2024
  9. www.biorxiv.org www.biorxiv.org
    Microglia aging in the hippocampus advances through intermediate states that drive inflammatory activation and cognitive decline
    1
    1. scibot 13 Apr 2024
      RRID:AB_2732849

      DOI: 10.1101/2024.04.09.588665

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    biorxiv.org/content/10.1101/2024.04.09.588665v1
  10. Feb 2024
  11. www.sciencedirect.com www.sciencedirect.com
    DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses
    1
    1. scibot 16 Feb 2024
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2024.113801

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    sciencedirect.com/science/article/pii/S2211124724001293
  12. www.sciencedirect.com www.sciencedirect.com
    Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective
    1
    1. scibot 02 Feb 2024
      RRID:AB_2732849

      DOI: 10.1016/j.neuron.2023.12.003

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    sciencedirect.com/science/article/pii/S0896627323009315
  13. Dec 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C1q is essential for myelination in the central nervous system (CNS)
    1
    1. scibot 13 Dec 2023
      RRID:AB_2732849

      DOI: 10.1016/j.isci.2023.108518

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    ncbi.nlm.nih.gov/pmc/articles/PMC10711495/
  15. Oct 2023
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of the parkinsonism-associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects
    1
    1. scibot 07 Oct 2023
      RRID:AB_2732849

      DOI: 10.1111/jnc.15962

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15962
  17. Sep 2023
  18. rupress.org rupress.org
    Maternal diet during early gestation influences postnatal taste activity–dependent pruning by microglia
    1
    1. scibot 23 Sep 2023
      RRID:AB_2732849

      DOI: 10.1084/jem.20212476

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    rupress.org/jem/article/220/12/e20212476/276286/Maternal-diet-during-early-gestation-influences
  19. Jul 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel phenotype of B cells associated with enhanced phagocytic capability and chemotactic function after ischemic stroke
    1
    1. scibot 25 Jul 2023
      RRID:AB_2732849

      DOI: 10.4103/1673-5374.371365

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    ncbi.nlm.nih.gov/pmc/articles/PMC10360087/
  21. Jun 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders
    1
    1. scibot 09 Jun 2023
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2023.112629

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    sciencedirect.com/science/article/pii/S221112472300640X
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Microglia enable cross-modal plasticity by removing inhibitory synapses
    1
    1. scibot 22 Apr 2023
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2023.112383

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    sciencedirect.com/science/article/pii/S2211124723003947
  25. Mar 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
    1
    1. scibot 17 Mar 2023
      RRID:AB_2732849

      DOI: 10.1016/j.cell.2023.02.023

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    sciencedirect.com/science/article/pii/S0092867423001666
  27. www.sciencedirect.com www.sciencedirect.com
    Physical exercise modulates the microglial complement pathway in mice to relieve cortical circuitry deficits induced by mutant human TDP-43
    1
    1. scibot 16 Mar 2023
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2023.112240

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    sciencedirect.com/science/article/pii/S2211124723002516
  28. www.sciencedirect.com www.sciencedirect.com
    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
    1
    1. scibot 10 Mar 2023
      RRID:AB_2732849

      DOI: 10.1016/j.bbi.2023.02.023

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    sciencedirect.com/science/article/pii/S0889159123000545
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain
    1
    1. scibot 19 Jan 2023
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2023.112010

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    sciencedirect.com/science/article/pii/S2211124723000219
  31. 52.53.155.43 52.53.155.43
    SSRN-id4232469-html.html
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    1. scibot 14 Jan 2023
      RRID:AB_2732849

      DOI: 10.2139/ssrn.4232469

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    52.53.155.43/960b1cd492db2ca950857c8e79a31c509b8c6378/SSRN-id4232469-html.html
  32. Nov 2022
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF-1 receptor related leukodystrophy
    1
    1. scibot 29 Nov 2022
      RRID:AB_2732849

      DOI: 10.1002/glia.24310

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    onlinelibrary.wiley.com/doi/10.1002/glia.24310
  34. May 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence
    1
    1. scibot 11 May 2022
      RRID:AB_2732849

      DOI: 10.7554/eLife.76564

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    ncbi.nlm.nih.gov/pmc/articles/PMC9071266/
  36. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
      RRID:AB_2732849

      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  37. Nov 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models
    1
    1. scibot 16 Nov 2021
      RRID:AB_2732849

      DOI: 10.1016/j.isci.2021.103245

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    ncbi.nlm.nih.gov/pmc/articles/PMC8561005/
  39. Aug 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
    1
    1. scibot 27 Aug 2021
      RRID:AB_2732849

      DOI: 10.1016/j.cell.2021.08.002

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    sciencedirect.com/science/article/pii/S0092867421009442
  41. Jul 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
    1
    1. scibot 30 Jul 2021
      RRID:AB_2732849

      DOI: 10.1016/j.neuron.2018.10.014

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    sciencedirect.com/science/article/pii/S0896627318309024
  43. www.sciencedirect.com www.sciencedirect.com
    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
    1
    1. scibot 22 Jul 2021
      ab182451

      DOI: 10.1016/j.celrep.2021.109399

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    sciencedirect.com/science/article/pii/S221112472100797X
  44. www.sciencedirect.com www.sciencedirect.com
    GABA-receptive microglia selectively sculpt developing inhibitory circuits
    1
    1. scibot 07 Jul 2021
      RRID:AB_2732849

      DOI: 10.1016/j.cell.2021.06.018

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    sciencedirect.com/science/article/pii/S0092867421007534
  45. May 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
    1
    1. scibot 08 May 2021
      RRID:AB_2732849

      DOI: 10.1016/j.neuron.2021.02.010

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    sciencedirect.com/science/article/pii/S0896627321000842
  47. Sep 2020
  48. www.jneurosci.org www.jneurosci.org
    Ocular dominance plasticity in binocular primary visual cortex does not require C1q
    1
    1. scibot 10 Sep 2020
      RRID:AB_2732849

      DOI: 10.1523/JNEUROSCI.1011-19.2019

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    jneurosci.org/content/40/4/769
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
    1
    1. scibot 13 Jan 2020
      RRID:AB_2732849

      DOI: 10.1016/j.celrep.2019.07.060

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    sciencedirect.com/science/article/pii/S2211124719309647
  51. www.sciencedirect.com www.sciencedirect.com
    The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.11.013

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    sciencedirect.com/science/article/pii/S2211124719314846
  52. www.sciencedirect.com www.sciencedirect.com
    Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.immuni.2019.12.004

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    sciencedirect.com/science/article/pii/S1074761319305230
  53. Nov 2018
  54. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/38/39/8329