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Jul 2025
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The knockout of Moesin leads to excess microglia-mediated synaptic pruning and impairs social novelty in a mouse model

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116012
  
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sciencedirect.com/science/article/pii/S2211124725007831
May 2025
elifesciences.org elifesciences.org

Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.97671
  
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elifesciences.org/articles/97671
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia remodeling in the visual thalamus of the DBA/2J mouse model of glaucoma

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1. scibot 21 May 2025
  
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  DOI: 10.1371/journal.pone.0323513
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12080812/
Jan 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

CD11c-Expressing Microglia Are Transient, Driven by Interactions With Apoptotic Cells

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1. scibot 24 Jan 2025
  
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  DOI: 10.1002/glia.24674
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24674
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cord

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1. scibot 23 Jan 2025
  
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  DOI: 10.1038/s42003-025-07506-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11739467/
Dec 2024
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Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.003
  
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sciencedirect.com/science/article/pii/S1074761324005132
Oct 2024
jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

Exercise training upregulates CD55 to suppress complement-mediated synaptic phagocytosis in Parkinson’s disease

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1. scibot 02 Oct 2024
  
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  DOI: 10.1186/s12974-024-03234-0
  
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jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-024-03234-0
Aug 2024
molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

1
1. scibot 02 Aug 2024
  
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  C1q
  
  DOI: 10.1186/s13024-021-00440-9
  
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molecularneurodegeneration.biomedcentral.com/article/10.1186/s13024-021-00440-9
Jul 2024
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Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain

1
1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.05.058
  
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sciencedirect.com/science/article/pii/S0092867424006391
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CD11c-expressing microglia are transient, driven by interactions with apoptotic cells

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1. scibot 04 Jul 2024
  
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  DOI: 10.1101/2024.06.24.600082
  
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biorxiv.org/content/10.1101/2024.06.24.600082v2
Apr 2024
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Microglia aging in the hippocampus advances through intermediate states that drive inflammatory activation and cognitive decline

1
1. scibot 13 Apr 2024
  
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  DOI: 10.1101/2024.04.09.588665
  
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biorxiv.org/content/10.1101/2024.04.09.588665v1
Feb 2024
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DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses

1
1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113801
  
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sciencedirect.com/science/article/pii/S2211124724001293
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Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective

1
1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.neuron.2023.12.003
  
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sciencedirect.com/science/article/pii/S0896627323009315
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

C1q is essential for myelination in the central nervous system (CNS)

1
1. scibot 13 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108518
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10711495/
Oct 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Loss of the parkinsonism-associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects

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1. scibot 07 Oct 2023
  
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  DOI: 10.1111/jnc.15962
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15962
Sep 2023
rupress.org rupress.org

Maternal diet during early gestation influences postnatal taste activity–dependent pruning by microglia

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1. scibot 23 Sep 2023
  
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  DOI: 10.1084/jem.20212476
  
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rupress.org/jem/article/220/12/e20212476/276286/Maternal-diet-during-early-gestation-influences
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel phenotype of B cells associated with enhanced phagocytic capability and chemotactic function after ischemic stroke

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1. scibot 25 Jul 2023
  
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  RRID:AB_2732849
  
  DOI: 10.4103/1673-5374.371365
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10360087/
Jun 2023
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Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders

1
1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112629
  
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sciencedirect.com/science/article/pii/S221112472300640X
Apr 2023
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Microglia enable cross-modal plasticity by removing inhibitory synapses

1
1. scibot 22 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112383
  
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sciencedirect.com/science/article/pii/S2211124723003947
Mar 2023
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Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration

1
1. scibot 17 Mar 2023
  
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  RRID:AB_2732849
  
  DOI: 10.1016/j.cell.2023.02.023
  
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sciencedirect.com/science/article/pii/S0092867423001666
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Physical exercise modulates the microglial complement pathway in mice to relieve cortical circuitry deficits induced by mutant human TDP-43

1
1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112240
  
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sciencedirect.com/science/article/pii/S2211124723002516
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Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy

1
1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.bbi.2023.02.023
  
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sciencedirect.com/science/article/pii/S0889159123000545
Jan 2023
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Time-dependent and selective microglia-mediated removal of spinal synapses in neuropathic pain

1
1. scibot 19 Jan 2023
  
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  RRID:AB_2732849
  
  DOI: 10.1016/j.celrep.2023.112010
  
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sciencedirect.com/science/article/pii/S2211124723000219
52.53.155.43 52.53.155.43

SSRN-id4232469-html.html

1
1. scibot 14 Jan 2023
  
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  RRID:AB_2732849
  
  DOI: 10.2139/ssrn.4232469
  
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52.53.155.43/960b1cd492db2ca950857c8e79a31c509b8c6378/SSRN-id4232469-html.html
Nov 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF-1 receptor related leukodystrophy

1
1. scibot 29 Nov 2022
  
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  RRID:AB_2732849
  
  DOI: 10.1002/glia.24310
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24310
May 2022
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Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

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1. scibot 11 May 2022
  
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  RRID:AB_2732849
  
  DOI: 10.7554/eLife.76564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9071266/
link.springer.com link.springer.com

Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy

1
1. scibot 05 May 2022
  
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  DOI: 10.1186/s13024-022-00526-y
  
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link.springer.com/article/10.1186/s13024-022-00526-y
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models

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1. scibot 16 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103245
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8561005/
Aug 2021
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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

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1. scibot 27 Aug 2021
  
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  DOI: 10.1016/j.cell.2021.08.002
  
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sciencedirect.com/science/article/pii/S0092867421009442
Jul 2021
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Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

1
1. scibot 30 Jul 2021
  
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  RRID:AB_2732849
  
  DOI: 10.1016/j.neuron.2018.10.014
  
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sciencedirect.com/science/article/pii/S0896627318309024
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Neuronal VCP loss of function recapitulates FTLD-TDP pathology

1
1. scibot 22 Jul 2021
  
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  ab182451
  
  DOI: 10.1016/j.celrep.2021.109399
  
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sciencedirect.com/science/article/pii/S221112472100797X
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GABA-receptive microglia selectively sculpt developing inhibitory circuits

1
1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.018
  
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sciencedirect.com/science/article/pii/S0092867421007534
May 2021
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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology

1
1. scibot 08 May 2021
  
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  DOI: 10.1016/j.neuron.2021.02.010
  
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sciencedirect.com/science/article/pii/S0896627321000842
Sep 2020
www.jneurosci.org www.jneurosci.org

Ocular dominance plasticity in binocular primary visual cortex does not require C1q

1
1. scibot 10 Sep 2020
  
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  RRID:AB_2732849
  
  DOI: 10.1523/JNEUROSCI.1011-19.2019
  
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jneurosci.org/content/40/4/769
Jan 2020
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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2732849
  
  DOI: 10.1016/j.celrep.2019.07.060
  
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The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA

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Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

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  DOI: 10.1016/j.immuni.2019.12.004
  
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Nov 2018
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jneurosci.org/content/38/39/8329