73 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule
    1
    1. scibot 05 Jun 2024
      RRID:AB_2732919

      DOI: 10.1016/j.cmet.2024.05.001

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    sciencedirect.com/science/article/pii/S1550413124001773
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    Quantitative trait loci mapping provides insights into the genetic regulation of dendritic cell numbers in mouse tissues
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114296

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    sciencedirect.com/science/article/pii/S2211124724006247
  4. May 2024
  5. www.sciencedirect.com www.sciencedirect.com
    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.immuni.2024.04.025

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    sciencedirect.com/science/article/pii/S1074761324002309
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.immuni.2024.04.026

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    sciencedirect.com/science/article/pii/S1074761324002310
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.cell.2024.04.025

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    sciencedirect.com/science/article/pii/S0092867424004513
  8. Apr 2024
  9. www.science.org www.science.org
    Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1126/scisignal.adh0439

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    science.org/doi/10.1126/scisignal.adh0439
  10. Mar 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides
    2
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113984

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    2. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113984

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    sciencedirect.com/science/article/pii/S2211124724003127
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    IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model
    1
    1. scibot 26 Mar 2024
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      DOI: 10.1038/s41467-024-45870-3

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    nature.com/articles/s41467-024-45870-3
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    Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis
    3
    1. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    2. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    3. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113934

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    sciencedirect.com/science/article/pii/S2211124724002626
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.immuni.2023.12.006

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    sciencedirect.com/science/article/pii/S107476132300537X
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113452

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    sciencedirect.com/science/article/pii/S221112472301464X
  18. Aug 2023
  19. www.sciencedirect.com www.sciencedirect.com
    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
    1
    1. scibot 25 Aug 2023
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      DOI: 10.1016/j.celrep.2023.113013

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    sciencedirect.com/science/article/pii/S2211124723010240
  20. www.sciencedirect.com www.sciencedirect.com
    CTLA-4 blockade induces CD4+ T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma
    1
    1. scibot 12 Aug 2023
      RRID:AB_2732919

      DOI: 10.1016/j.immuni.2023.07.015

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    sciencedirect.com/science/article/abs/pii/S107476132300328X
  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.002

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    sciencedirect.com/science/article/pii/S0092867423006426
  23. Jun 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model
    2
    1. scibot 30 Jun 2023
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      DOI: 10.1016/j.isci.2023.106963

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    2. scibot 30 Jun 2023
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      DOI: 10.1016/j.isci.2023.106963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291467/
  25. May 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
    1
    1. scibot 26 May 2023
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      DOI: 10.1016/j.ccell.2023.04.018

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    sciencedirect.com/science/article/pii/S1535610823001629
  27. Apr 2023
  28. www.sciencedirect.com www.sciencedirect.com
    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112436

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    sciencedirect.com/science/article/pii/S2211124723004473
  29. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
    1
    1. scibot 14 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.015

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    sciencedirect.com/science/article/pii/S1535610823000880
  30. Feb 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection
    1
    1. scibot 23 Feb 2023
      RRID:AB_2732919

      DOI: 10.1016/j.isci.2023.106059

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942003/
  32. www.sciencedirect.com www.sciencedirect.com
    OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
    1
    1. scibot 16 Feb 2023
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      DOI: 10.1016/j.xcrm.2023.100939

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    sciencedirect.com/science/article/pii/S2666379123000319
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    Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
    1
    1. scibot 02 Feb 2023
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      DOI: 10.1016/j.immuni.2023.01.003

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    sciencedirect.com/science/article/pii/S1074761323000134
  34. Jan 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1158/2326-6066.CIR-21-0691

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    ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
  36. Dec 2022
  37. academic.oup.com academic.oup.com
    Nur77-Tempo mice reveal T cell steady state antigen recognition
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1093/discim/kyac009

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    academic.oup.com/discovimmunology/article/1/1/kyac009/6835142
  38. www.sciencedirect.com www.sciencedirect.com
    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
    1
    1. scibot 17 Dec 2022
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      DOI: 10.1016/j.ccell.2022.11.014

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    sciencedirect.com/science/article/pii/S153561082200561X
  39. www.sciencedirect.com www.sciencedirect.com
    Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity
    1
    1. scibot 11 Dec 2022
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      DOI: 10.1016/j.chom.2022.10.014

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    sciencedirect.com/science/article/pii/S1931312822005273
  40. 52.53.155.43 52.53.155.43
    can-22-1046-html.html
    1
    1. scibot 01 Dec 2022
      AB_2732919

      DOI: 10.1158/0008-5472.CAN-22-1046

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    52.53.155.43/31121aea6deac1c0e5bfa6acfce4eeee5d0658c1/can-22-1046-html.html
  41. Nov 2022
  42. www.sciencedirect.com www.sciencedirect.com
    STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation
    1
    1. scibot 29 Nov 2022
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      DOI: 10.1016/j.immuni.2022.11.001

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    sciencedirect.com/science/article/pii/S107476132200591X
  43. www.science.org www.science.org
    IFN-γ–dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis
    1
    1. scibot 04 Nov 2022
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      DOI: 10.1126/sciadv.abl5162

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    science.org/doi/10.1126/sciadv.abl5162
  44. Aug 2022
  45. www.sciencedirect.com www.sciencedirect.com
    CD8 memory precursor cell generation is a continuous process
    1
    1. scibot 30 Aug 2022
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      DOI: 10.1016/j.isci.2022.104927

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    sciencedirect.com/science/article/pii/S2589004222011993
  46. Jul 2022
  47. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Using Full-Spectrum Flow Cytometry to Phenotype Memory T and NKT Cell Subsets with Optimized Tissue-Specific Preparation Protocols
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1002/cpz1.482

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.482
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    1. scibot 12 Jul 2022
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      DOI: 10.1158/1541-7786.MCR-21-0560

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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
  49. Jun 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IFN-γ–dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1126/sciadv.abl5162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9176743/
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    A humanized β2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110876

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    sciencedirect.com/science/article/pii/S2211124722006519
  52. May 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages
    1
    1. scibot 19 May 2022
      RRID:AB_2732919

      DOI: 10.1016/j.celrep.2022.110819

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    sciencedirect.com/science/article/pii/S2211124722005903
  54. Dec 2021
  55. insight.jci.org insight.jci.org
    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
    1
    1. scibot 22 Dec 2021
      RRID:AB_2732919

      DOI: 10.1172/jci.insight.151797

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    insight.jci.org/articles/view/151797
  56. www.sciencedirect.com www.sciencedirect.com
    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
    1
    1. scibot 21 Dec 2021
      RRID:AB_2732919

      DOI: 10.1016/j.immuni.2021.11.017

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    sciencedirect.com/science/article/pii/S1074761321005094
  57. www.sciencedirect.com www.sciencedirect.com
    The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota
    1
    1. scibot 09 Dec 2021
      RRID:AB_2732919

      DOI: 10.1016/j.xcrm.2021.100464

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    sciencedirect.com/science/article/pii/S2666379121003360
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    Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses
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  59. Nov 2021
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    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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    MicroRNA-29 specifies age-related differences in the CD8+ T cell immune response
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  63. Oct 2021
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    Cold exposure protects from neuroinflammation through immunologic reprogramming
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  65. Sep 2021
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    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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    Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
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    Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength
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    Flow cytometric characterization of tissue-resident lymphocytes after murine liver and heart transplantation
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  70. Aug 2021
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    The composition of the gut microbiota following early-life antibiotic exposure affects host health and longevity in later life
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    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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  74. Jul 2021
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    MYC deficiency impairs the development of effector/memory T lymphocytes
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  76. Jun 2021
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    Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
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  78. May 2021
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    Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation
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    An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development
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    Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β
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  82. Apr 2021
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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  84. Feb 2021
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    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
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  86. Jan 2021
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    Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry
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  88. Nov 2020
  89. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration
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  90. Sep 2020
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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    Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
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    Impaired phagocytic function in CX3CR1+ tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice
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      CD8 clone 53‐6.7 BUV395

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  94. Jan 2020
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    RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
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    Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence
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    PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage
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    Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation
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    Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells
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    Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
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