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Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases

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1. scibot 19 Dec 2025
  
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  RRID:AB_2736998
  
  DOI: 10.1158/0008-5472.CAN-24-3723
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12170161/
Dec 2025
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PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells

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1. scibot 05 Dec 2025
  
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  DOI: 10.1158/1541-7786.MCR-25-0211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12671455/
Nov 2025
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Paneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer

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1. scibot 15 Nov 2025
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.ccell.2025.10.010
  
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sciencedirect.com/science/article/pii/S1535610825004519
Aug 2025
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SMAD4 Deficiency Promotes Pancreatic Cancer Progression and Confers Susceptibility to TGFβ Inhibition

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1. scibot 19 Aug 2025
  
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  RRID:AB_2736998
  
  DOI: 10.1158/0008-5472.CAN-24-1970
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12355175/
Jul 2025
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Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer

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1. scibot 10 Jul 2025
  
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  DOI: 10.1186/s12964-025-02337-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12235933/
Mar 2025
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ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma

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1. scibot 29 Mar 2025
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.xcrm.2025.102038
  
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sciencedirect.com/science/article/pii/S2666379125001119
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CD4+ anti-TGF-β CAR T cells and CD8+ conventional CAR T cells exhibit synergistic antitumor effects

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102020
  
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sciencedirect.com/science/article/pii/S266637912500093X
Feb 2025
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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-22-3009
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
Jan 2025
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ERBB4 selectively amplifies TGF-β pro-metastatic responses

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1. scibot 24 Jan 2025
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.celrep.2024.115210
  
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sciencedirect.com/science/article/pii/S2211124724015614
Dec 2024
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Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101838
  
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sciencedirect.com/science/article/pii/S2666379124006098
Sep 2024
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TGF-β and RAS jointly unmask primed enhancers to drive metastasis

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.014
  
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sciencedirect.com/science/article/pii/S009286742400905X
May 2024
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Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging

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1. scibot 08 May 2024
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.isci.2024.109708
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11066433/
Feb 2024
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Stromal-derived MAOB promotes prostate cancer growth and progression

1
1. scibot 14 Feb 2024
  
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  RRID:AB_2736998
  
  DOI: 10.1126/sciadv.adi4935
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
Dec 2023
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Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling

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1. scibot 16 Dec 2023
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.devcel.2023.11.020
  
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sciencedirect.com/science/article/pii/S1534580723006184
Jun 2023
52.53.155.43 52.53.155.43

TOPK mediates immune evasion of Renal Cell Carcinoma via upregulating the expression of PD-L1

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1. scibot 30 Jun 2023
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.isci.2023.107185
  
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52.53.155.43/9a5455060dac46a2102bae7baf607274e71beaee/1-s2.0-S2589004223012622-main-html.html
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Acetate controls endothelial-to-mesenchymal transition

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1. scibot 21 Jun 2023
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.cmet.2023.05.010
  
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sciencedirect.com/science/article/pii/S1550413123002036
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5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

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1. scibot 02 Jun 2023
  
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  AB_2736998
  
  DOI: 10.1016/j.celrep.2023.112560
  
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sciencedirect.com/science/article/pii/S2211124723005715
Mar 2023
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Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex

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1. scibot 10 Mar 2023
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.yexcr.2023.113544
  
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sciencedirect.com/science/article/pii/S0014482723000915
Jan 2023
academic.oup.com academic.oup.com

Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2

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1. scibot 06 Jan 2023
  
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  AB_2736998
  
  DOI: 10.1210/endocr/bqac210
  
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academic.oup.com/endo/article/164/2/bqac210/6916877
Aug 2021
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Distal Enhancer Potentiates Activin- and GnRH-Induced Transcription of FSHB

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1. scibot 14 Aug 2021
  
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  DOI: 10.1210/endocr/bqab069
  
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academic.oup.com/endo/article/162/7/bqab069/6213400
Jan 2020
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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

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1. scibot 13 Jan 2020
  
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  RRID:AB_2736998
  
  DOI: 10.1016/j.immuni.2019.09.002
  
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  Curator: @ethanbadger
  
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  RRID:AB_2736998 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319303735