43 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
    1
    1. scibot 16 Nov 2024
      RRID:AB_2737000

      DOI: 10.1016/j.cell.2024.10.010

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    sciencedirect.com/science/article/pii/S0092867424011589
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.xcrm.2024.101753

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    sciencedirect.com/science/article/pii/S266637912400483X
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application
    1
    1. scibot 02 Oct 2024
      RRID:AB_2737000

      DOI: 10.1038/s41467-024-52110-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11427689/
  6. Sep 2024
  7. www.nature.com www.nature.com
    Activation of the NLRP1B inflammasome by caspase-8
    1
    1. scibot 25 Sep 2024
      RRID:AB_2737000

      DOI: 10.1038/s42003-024-06882-3

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    nature.com/articles/s42003-024-06882-3
  8. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
    1
    1. scibot 11 Sep 2024
      AB_2737000

      DOI: 10.1016/j.celrep.2024.114728

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    sciencedirect.com/science/article/pii/S2211124724010799
  9. www.sciencedirect.com www.sciencedirect.com
    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
    1
    1. scibot 10 Sep 2024
      AB_2737000

      DOI: 10.1016/j.cell.2024.08.007

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    sciencedirect.com/science/article/pii/S0092867424008985
  10. Jun 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
    1
    1. scibot 21 Jun 2024
      RRID:AB_2737000

      DOI: 10.1016/j.cell.2024.05.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
  12. Apr 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyroptotic T cell-derived active IL-16 has a driving function in ovarian endometriosis development
    1
    1. scibot 03 Apr 2024
      RRID:AB_2737000

      DOI: 10.1016/j.xcrm.2024.101476

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983113/
  14. Mar 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
    2
    1. scibot 06 Mar 2024
      AB_2737000

      DOI: 10.1158/1535-7163.MCT-23-0025

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    2. scibot 06 Mar 2024
      AB_2737000

      DOI: 10.1158/1535-7163.MCT-23-0025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  16. Feb 2024
  17. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 16 Feb 2024
      RRID:AB_2737000

      DOI: 10.1111/bph.16299

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16299
  18. Dec 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
    1
    1. scibot 02 Dec 2023
      RRID:AB_2737000

      DOI: 10.1016/j.xcrm.2023.101245

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    sciencedirect.com/science/article/pii/S2666379123004226
  20. www.nature.com www.nature.com
    Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
    1
    1. scibot 02 Dec 2023
      RRID:AB_2737000

      DOI: 10.1038/s41467-023-43707-z

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    nature.com/articles/s41467-023-43707-z
  21. Sep 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores
    1
    1. scibot 08 Sep 2023
      AB_2737000

      DOI: 10.1016/j.isci.2023.107698

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    ncbi.nlm.nih.gov/pmc/articles/PMC10480325/
  23. Aug 2023
  24. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
    1
    1. scibot 11 Aug 2023
      RRID:AB_2737000

      DOI: 10.1158/1535-7163.mct-23-0025

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    52.53.155.43/1629e82c15a2ef751662f24158b1c1b52e5a2112/mct-23-0025 (1)-html.html
  25. Jun 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Whole-genome CRISPR screen identifies RAVER1 regulates RIPK1-mediated inflammatory cell death, PANoptosis
    1
    1. scibot 09 Jun 2023
      RRID:AB_2737000

      DOI: 10.1016/j.isci.2023.106938

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    sciencedirect.com/science/article/pii/S2589004223010155
  27. www.sciencedirect.com www.sciencedirect.com
    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
    1
    1. scibot 02 Jun 2023
      RRID:AB_2737000

      DOI: 10.1016/j.cell.2023.05.005

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    sciencedirect.com/science/article/pii/S009286742300524X
  28. Mar 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
    1
    1. scibot 16 Mar 2023
      RRID:AB_2737000

      DOI: 10.1016/j.neuron.2023.02.019

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    sciencedirect.com/science/article/pii/S089662732300123X
  30. Jan 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
    1
    1. scibot 20 Jan 2023
      RRID:AB_2737000

      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  32. www.sciencedirect.com www.sciencedirect.com
    Bile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions
    1
    1. scibot 19 Jan 2023
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2023.112011

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    sciencedirect.com/science/article/pii/S2211124723000220
  33. Dec 2022
  34. www.science.org www.science.org
    Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies
    1
    1. scibot 24 Dec 2022
      AB_2737000

      DOI: 10.1126/scisignal.abl6781

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    science.org/doi/10.1126/scisignal.abl6781
  35. aacrjournals.org aacrjournals.org
    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
    1
    1. scibot 04 Dec 2022
      AB_2737000

      DOI: 10.1158/1541-7786.MCR-22-0040

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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  36. Nov 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    1
    1. scibot 24 Nov 2022
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2022.111688

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    sciencedirect.com/science/article/pii/S2211124722015625
  38. Oct 2022
  39. 52.53.155.43 52.53.155.43
    mcr-22-0040-html.html
    1
    1. scibot 28 Oct 2022
      RRID:AB_2737000

      DOI: 10.1158/1541-7786.MCR-22-0040

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    52.53.155.43/727478f306d650986e0e949733013801988f63e4/mcr-22-0040-html.html
  40. pubs.acs.org pubs.acs.org
    LANCE: a Label-Free Live Apoptotic and Necrotic Cell Explorer Using Convolutional Neural Network Image Analysis
    1
    1. scibot 21 Oct 2022
      RRID:AB_2737000

      DOI: 10.1021/acs.analchem.2c00878

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    pubs.acs.org/doi/10.1021/acs.analchem.2c00878
  41. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
    1. scibot 05 Oct 2022
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2022.111434

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    sciencedirect.com/science/article/pii/S221112472201275X
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
    1
    1. scibot 02 Oct 2022
      RRID:AB_2737000

      DOI: 10.1016/j.isci.2022.105118

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
  43. May 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells
    1
    1. scibot 20 May 2022
      RRID:AB_2737000

      DOI: 10.1016/j.molcel.2022.04.033

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    sciencedirect.com/science/article/pii/S1097276522004336
  45. Mar 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
    1
    1. scibot 27 Mar 2022
      RRID:AB_2737000

      DOI: 10.1016/j.molcel.2022.03.010

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    sciencedirect.com/science/article/pii/S1097276522002192
  47. www.sciencedirect.com www.sciencedirect.com
    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
    1
    1. scibot 15 Mar 2022
      RRID:AB_2737000

      DOI: 10.1016/j.cmet.2022.02.010

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    sciencedirect.com/science/article/pii/S1550413122000547
  48. Oct 2021
  49. www.sciencedirect.com www.sciencedirect.com
    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
    1
    1. scibot 21 Oct 2021
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2021.109858

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    sciencedirect.com/science/article/pii/S2211124721013255
  50. www.sciencedirect.com www.sciencedirect.com
    Dihydroartemisinin mediating PKM2-caspase-8/3-GSDME axis for pyroptosis in esophageal squamous cell carcinoma
    1
    1. scibot 15 Oct 2021
      ab215191

      DOI: 10.1016/j.cbi.2021.109704

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    sciencedirect.com/science/article/pii/S0009279721003422
  51. Aug 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shigella OspC3 suppresses murine cytosolic LPS sensing
    1
    1. scibot 19 Aug 2021
      RRID:AB_2737000

      DOI: 10.1016/j.isci.2021.102910

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    ncbi.nlm.nih.gov/pmc/articles/PMC8361271/
  53. Jul 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2018.10.103

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    sciencedirect.com/science/article/pii/S221112471831725X
  55. Jun 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn’s disease by promoting intestinal inflammation
    1
    1. scibot 16 Jun 2021
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2021.109265

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    sciencedirect.com/science/article/pii/S221112472100632X
  57. May 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
    1
    1. scibot 12 May 2021
      RRID:AB_2737000

      DOI: 10.1016/j.immuni.2021.04.012

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    sciencedirect.com/science/article/pii/S1074761321001746
  59. Apr 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
    1
    1. scibot 30 Apr 2021
      RRID:AB_2737000

      DOI: 10.1016/j.cmet.2020.11.018

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    sciencedirect.com/science/article/pii/S1550413120306537
  61. www.sciencedirect.com www.sciencedirect.com
    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
    1
    1. scibot 14 Apr 2021
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2021.108998

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    sciencedirect.com/science/article/pii/S2211124721003120
  62. Dec 2020
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
    1
    1. scibot 10 Dec 2020
      RRID:AB_2737000

      DOI: 10.1016/j.cell.2020.11.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674074/
  64. Sep 2020
  65. www.sciencedirect.com www.sciencedirect.com
    A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
    1
    1. scibot 26 Sep 2020
      RRID:AB_2737000

      DOI: 10.1016/j.celrep.2020.03.030

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      RRIDCUR:Validated RRID:AB_2737000
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    sciencedirect.com/science/article/pii/S2211124720303442
  66. www.sciencedirect.com www.sciencedirect.com
    Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis
    1
    1. scibot 15 Sep 2020
      RRID:AB_2737000

      DOI: 10.1016/j.cell.2020.02.002

      Resource: (Abcam Cat# ab215191, RRID:AB_2737000)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2737000

      What is this?
      RRID:AB_2737000 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286742030146X
  67. Jan 2020
  68. iovs.arvojournals.org iovs.arvojournals.org
    Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal
    1
    1. scibot 13 Jan 2020
      RRID:AB_2737000

      DOI: 10.1167/iovs.18-26360

      Resource: (Abcam Cat# ab215191, RRID:AB_2737000)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2737000

      What is this?

      RRID:AB_2737000 RRIDCUR:Validated
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    iovs.arvojournals.org/article.aspx
  69. www.sciencedirect.com www.sciencedirect.com
    Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure
    1
    1. scibot 13 Jan 2020
      RRID:AB_2737000

      DOI: 10.1016/j.immuni.2019.11.005

      Resource: (Abcam Cat# ab215191, RRID:AB_2737000)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2737000

      What is this?

      RRID:AB_2737000 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319304637