39 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
    1
    1. scibot 07 Nov 2024
      RRID:AB_2737062

      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    1
    1. scibot 26 Sep 2024
      RRID:AB_2737062

      DOI: 10.1016/j.isci.2024.110693

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
    1
    1. scibot 01 Aug 2024
      AB_2737062

      DOI: 10.1016/j.molcel.2024.07.003

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    sciencedirect.com/science/article/pii/S1097276524005793
  7. Jul 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
    1
    1. scibot 27 Jul 2024
      RRID:AB_2737062

      DOI: 10.1016/j.isci.2024.110285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  9. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
    1
    1. scibot 24 Jul 2024
      AB_2737062

      DOI: 10.1016/j.molcel.2024.06.001

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    sciencedirect.com/science/article/pii/S1097276524004799
  10. May 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Development of nitroalkene-based inhibitors to target STING-dependent inflammation
    1
    1. scibot 23 May 2024
      RRID:AB_2737062

      DOI: 10.1016/j.redox.2024.103202

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    sciencedirect.com/science/article/pii/S2213231724001800
  12. Apr 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      RRID:AB_2737062

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
    1
    1. scibot 28 Apr 2024
      RRID:AB_2737062

      DOI: 10.1101/2024.04.07.588166

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030420/
  15. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    1. scibot 26 Apr 2024
      RRID:AB_2737062

      DOI: 10.1016/j.ccell.2024.04.004

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    sciencedirect.com/science/article/pii/S1535610824001284
  16. www.sciencedirect.com www.sciencedirect.com
    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2024.114088

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    sciencedirect.com/science/article/pii/S2211124724004169
  17. Mar 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
    2
    1. scibot 05 Mar 2024
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2024.113886

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    2. scibot 05 Mar 2024
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2024.113886

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019558/
  19. www.sciencedirect.com www.sciencedirect.com
    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
    2
    1. scibot 01 Mar 2024
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2024.113870

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    2. scibot 01 Mar 2024
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2024.113870

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    sciencedirect.com/science/article/pii/S2211124724001980
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis
    1
    1. scibot 28 Nov 2023
      RRID:AB_2737062

      DOI: 10.1016/j.immuni.2023.11.001

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    sciencedirect.com/science/article/abs/pii/S1074761323004582
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
    1
    1. scibot 27 Oct 2023
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2023.113277

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    sciencedirect.com/science/article/pii/S2211124723012895
  24. Jul 2023
  25. www.sciencedirect.com www.sciencedirect.com
    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
    1
    1. scibot 21 Jul 2023
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2023.112805

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    sciencedirect.com/science/article/pii/S2211124723008161
  26. May 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
    1
    1. scibot 27 May 2023
      RRID:AB_2737062

      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  28. Apr 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
    1
    1. scibot 29 Apr 2023
      RRID:AB_2737062

      DOI: 10.1016/j.xcrm.2023.101024

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    sciencedirect.com/science/article/pii/S2666379123001349
  30. Mar 2023
  31. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
    1
    1. scibot 28 Mar 2023
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2023.112306

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    sciencedirect.com/science/article/pii/S2211124723003170
  32. Dec 2022
  33. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
    2
    1. scibot 31 Dec 2022
      RRID:AB_2737062

      DOI: 10.15252/embj.2022111961

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    2. scibot 31 Dec 2022
      RRID:AB_2737062

      DOI: 10.15252/embj.2022111961

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    embopress.org/doi/10.15252/embj.2022111961
  34. Nov 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manganese enhances DNA- or RNA-mediated innate immune response by inducing phosphorylation of TANK-binding kinase 1
    1
    1. scibot 04 Nov 2022
      RRID:AB_2737062

      DOI: 10.1016/j.isci.2022.105352

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    ncbi.nlm.nih.gov/pmc/articles/PMC9619380/
  36. Sep 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Ku proteins promote DNA binding and condensation of cyclic GMP-AMP synthase
    1
    1. scibot 08 Sep 2022
      RRID:AB_2920552

      DOI: 10.1016/j.celrep.2022.111310

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S2211124722011342
  38. www.sciencedirect.com www.sciencedirect.com
    ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
    1
    1. scibot 07 Sep 2022
      RRID:AB_2737062

      DOI: 10.1016/j.immuni.2022.08.006

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    sciencedirect.com/science/article/pii/S1074761322003995
  39. Jun 2022
  40. rupress.org rupress.org
    ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
    1
    1. scibot 09 Jun 2022
      RRID:AB_2737062

      DOI: 10.1083/jcb.202106046

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    rupress.org/jcb/article/221/7/e202106046/213259/ER-lysosome-lipid-transfer-protein-VPS13C-PARK23
  41. May 2022
  42. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
    1
    1. scibot 26 May 2022
      AB_2737062

      DOI: 10.1016/j.celrep.2022.110856

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    sciencedirect.com/science/article/pii/S2211124722006295
  43. www.sciencedirect.com www.sciencedirect.com
    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
    1
    1. scibot 19 May 2022
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2022.110814

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    sciencedirect.com/science/article/pii/S221112472200585X
  44. www.sciencedirect.com www.sciencedirect.com
    Protocol to induce and assess cGAS-STING pathway activation in vitro
    1
    1. scibot 18 May 2022
      RRID:AB_2737062

      DOI: 10.1016/j.xpro.2022.101384

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    sciencedirect.com/science/article/pii/S2666166722002647
  45. Nov 2021
  46. www.sciencedirect.com www.sciencedirect.com
    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
    1
    1. scibot 09 Nov 2021
      RRID:AB_2737062

      DOI: 10.1016/j.immuni.2021.10.004

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    sciencedirect.com/science/article/pii/S1074761321004106
  47. May 2021
  48. www.sciencedirect.com www.sciencedirect.com
    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
    1
    1. scibot 09 May 2021
      RRID:AB_2737062

      DOI: 10.1016/j.stem.2020.06.022

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    sciencedirect.com/science/article/pii/S1934590920302897
  49. www.sciencedirect.com www.sciencedirect.com
    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
    1
    1. scibot 08 May 2021
      RRID:AB_2737062

      DOI: 10.1016/j.molcel.2021.02.038

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    sciencedirect.com/science/article/pii/S1097276521001684
  50. www.sciencedirect.com www.sciencedirect.com
    SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function
    1
    1. scibot 08 May 2021
      RRID:AB_2737062

      DOI: 10.1016/j.molcel.2020.12.024

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    sciencedirect.com/science/article/pii/S109727652030945X
  51. www.sciencedirect.com www.sciencedirect.com
    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    1
    1. scibot 08 May 2021
      RRID:AB_2737062

      DOI: 10.1016/j.molcel.2020.10.021

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    sciencedirect.com/science/article/pii/S1097276520307280
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 suppresses innate immune signaling to promote tumorigenesis
    1
    1. scibot 22 Apr 2021
      RRID:AB_2737062

      DOI: 10.1016/j.ccell.2021.01.003

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    sciencedirect.com/science/article/pii/S1535610821000416
  54. www.sciencedirect.com www.sciencedirect.com
    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
    1
    1. scibot 17 Apr 2021
      RRID:AB_2737062

      DOI: 10.1016/j.ccell.2020.05.020

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    sciencedirect.com/science/article/pii/S1535610820302701
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
    1
    1. scibot 17 Sep 2020
      RRID:AB_2737062

      DOI: 10.1016/j.celrep.2020.03.056

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    sciencedirect.com/science/article/pii/S2211124720303703
  57. www.cell.com www.cell.com
    The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING
    1
    1. scibot 04 Sep 2020
      RRID: AB_2737062

      DOI: 10.1016/j.celrep.2018.11.097

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      Curator: @evieth

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    cell.com/cell-reports/fulltext/S2211-1247(18)31888-6
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING
    1
    1. scibot 12 Jan 2020
      RRID:AB_2737062

      DOI: 10.1016/j.molcel.2019.02.038

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    sciencedirect.com/science/article/pii/S1097276519301492