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Targeted inhibition of M2 macrophages polarization via a PDC attenuates chronic pancreatitis through the PPARα pathway

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114839
  
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sciencedirect.com/science/article/pii/S2589004226002142
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD

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1. scibot 04 Feb 2026
  
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  DOI: 10.1016/j.isci.2025.114596
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12856326/
Jan 2026
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Stuxnet balances mitochondria homeostasis by regulating uhg5 and parkin

1
1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116855
  
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sciencedirect.com/science/article/pii/S2211124725016274
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Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo

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1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.007
  
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sciencedirect.com/science/article/pii/S0092867425014205
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116745
  
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sciencedirect.com:5037/science/article/pii/S2211124725015177
Oct 2025
www.embopress.org www.embopress.org

PIWI proteins tether the piRNA biogenesis machinery to mitochondria during mammalian spermatogenesis

1
1. scibot 07 Oct 2025
  
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  DOI: 10.1038/s44318-025-00579-x
  
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embopress.org/doi/10.1038/s44318-025-00579-x
54.241.53.176 54.241.53.176

gao-et-al-2025-piwi-proteins-tether-the-pirna-biogenesis-machinery-to-mitochondria-during-mammalian-spermatogenesis-html.html

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1. scibot 07 Oct 2025
  
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  DOI: 10.1038/s44318-025-00579-x
  
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54.241.53.176/1dfa48b35fe299db16c3f700198d4182096b01db/gao-et-al-2025-piwi-proteins-tether-the-pirna-biogenesis-machinery-to-mitochondria-during-mammalian-spermatogenesis-html.html
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Control of Inflammatory Response by Tissue Microenvironment

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1. scibot 24 Sep 2025
  
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  DOI: 10.1101/2024.05.10.592432
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11118380/
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Trefoil factor 2 interacts with A4GNT to regulate inflammation to protect against pneumonia during influenza virus infection

1
1. scibot 09 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113370
  
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sciencedirect.com/science/article/pii/S2589004225016311
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Sensitive and specific affinity purification-mass spectrometry assisted by PafA-mediated proximity labeling

1
1. scibot 09 Sep 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.crmeth.2025.101166
  
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sciencedirect.com/science/article/pii/S2667237525002024
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CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma

1
1. scibot 07 Sep 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1136/jitc-2025-012118
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12382581/
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SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer

1
1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116139
  
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sciencedirect.com/science/article/pii/S2211124725009106
Jul 2025
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Identification of a Novel Gene ARNT2 for Osteogenic Differentiation of Mesenchymal Stem Cells

1
1. scibot 22 Jul 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1007/s00223-025-01407-4
  
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link.springer.com/article/10.1007/s00223-025-01407-4
Jun 2025
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GJB2 enhances cancer stem cell properties by modulating SOX2 expression via NF-κB pathway activation in lung adenocarcinoma

1
1. scibot 18 Jun 2025
  
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  RRID:AB_2737399
  
  DOI: 10.21037/tcr-24-2075
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169982/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Integrative Analysis of DNA Methylation and Gene Expression Reveals Key Molecular Signatures in Spatial Memory Impairment of Sepsis-Associated Encephalopathy

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1. scibot 18 Jun 2025
  
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  DOI: 10.1111/jnc.70120
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70120
May 2025
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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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1. scibot 17 May 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.celrep.2025.115679
  
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sciencedirect.com/science/article/pii/S2211124725004504
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

1
1. scibot 13 Mar 2025
  
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  RRID:AB_2737399
  
  DOI: 10.7554/eLife.101173
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11896613/
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Injectable hydrogel with miR-222-engineered extracellular vesicles ameliorates myocardial ischemic reperfusion injury via mechanotransduction

1
1. scibot 04 Mar 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.xcrm.2025.101987
  
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sciencedirect.com/science/article/pii/S2666379125000606
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

1
1. scibot 16 Feb 2025
  
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  DOI: 10.7554/eLife.100820
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11828483/
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GEVSod2 Powder: A Modified Product Based on Biovesicles Functioned in Air Pollution PM2.5-Induced Cardiopulmonary Injury

1
1. scibot 15 Feb 2025
  
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  RRID:AB_2737399
  
  DOI: 10.34133/research.0609
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11822167/
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SENP1 decreases RNF168 phase separation to promote DNA damage repair and drug resistance in colon cancer

1
1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-22-4017
  
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aacrjournals.org/cancerres/article/83/17/2908/728579/SENP1-Decreases-RNF168-Phase-Separation-to-Promote
Jan 2025
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Comparative proteomic landscapes elucidate human preimplantation development and failure

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1. scibot 24 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.028
  
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sciencedirect.com/science/article/pii/S0092867424014703
www.cell.com www.cell.com

Mouse totipotent blastomere-like cells model embryogenesis from zygotic genome activation to post implantation

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1. scibot 23 Jan 2025
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.stem.2024.12.006
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(24)00446-6
Dec 2024
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MAPK pathways regulated apoptosis and pyroptosis in respiratory epithelial cells of a primitive vertebrate model during bacterial infection

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.ijbiomac.2024.138587
  
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sciencedirect.com/science/article/pii/S014181302409398X
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Chelerythrine triggers the prolongation of QT interval and induces cardiotoxicity by promoting the degradation of hERG channels

1
1. scibot 02 Dec 2024
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.jbc.2024.108023
  
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sciencedirect.com/science/article/pii/S0021925824025250
Nov 2024
www.cell.com www.cell.com

Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling

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1. scibot 26 Nov 2024
  
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  AB_2737399
  
  DOI: 10.1016/j.molcel.2022.10.009
  
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cell.com/molecular-cell/fulltext/S1097-2765(22)00966-2
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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1. scibot 02 Oct 2024
  
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  DOI: 10.4103/NRR.NRR-D-23-01446
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11433904/
Jul 2024
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A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.molcel.2024.06.005
  
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sciencedirect.com/science/article/pii/S1097276524004830
Jun 2024
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The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114366
  
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sciencedirect.com/science/article/pii/S2211124724006946
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Capturing totipotency in human cells through spliceosomal repression

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1. scibot 06 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.010
  
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sciencedirect.com/science/article/pii/S0092867424005191
May 2024
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Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response

1
1. scibot 30 May 2024
  
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  DOI: 10.1016/j.ebiom.2024.105162
  
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sciencedirect.com/science/article/pii/S235239642400197X
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis

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1. scibot 30 Apr 2024
  
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  RRID: AB_2737399
  
  DOI: 10.1186/s13578-024-01230-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
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Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21

1
1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114095
  
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sciencedirect.com/science/article/pii/S2211124724004236
Feb 2024
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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

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1. scibot 29 Feb 2024
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.molcel.2024.02.002
  
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sciencedirect.com/science/article/pii/S1097276524000984
Jan 2024
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First Evidence of Mineralocorticoid Receptor Gene and Protein Expression in Rat and Human Thyroid Tissues and Cell Cultures

1
1. scibot 10 Jan 2024
  
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  RRID:AB_2737399
  
  DOI: 10.3390/ijms25020754
  
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mdpi.com/1422-0067/25/2/754
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Germline gene fusions across species reveal the chromosomal instability regions and cancer susceptibility

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.isci.2023.108431
  
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sciencedirect.com/science/article/pii/S2589004223025087
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ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress

1
1. scibot 17 Nov 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.celrep.2023.113402
  
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sciencedirect.com/science/article/pii/S2211124723014146
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer

1
1. scibot 31 Oct 2023
  
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  RRID:AB_2737399
  
  DOI: 10.3390/cancers15205082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10605716/
Sep 2023
www.cell.com www.cell.com

Structural basis of CD97 activation and G-protein coupling

1
1. scibot 07 Sep 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.chembiol.2023.08.003
  
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cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00275-1
Aug 2023
52.53.155.43 52.53.155.43

can-22-4017-html.html

2
1. scibot 04 Aug 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1158/0008-5472.can-22-4017
  
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2. scibot 04 Aug 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1158/0008-5472.can-22-4017
  
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52.53.155.43/9095f2133470165b212e6a97c53f24a603903e15/can-22-4017 (1)-html.html
May 2023
www.sciencedirect.com www.sciencedirect.com

A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response

1
1. scibot 18 May 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.isci.2023.106808
  
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sciencedirect.com/science/article/pii/S2589004223008854
Mar 2023
www.ijbs.com www.ijbs.com

IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins

1
1. scibot 30 Mar 2023
  
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  RRID:AB_2737399
  
  DOI: 10.7150/ijbs.78248
  
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ijbs.com/v19p1490.htm
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chidamide suppresses adipogenic differentiation of bone marrow derived mesenchymal stem cells via increasing REEP2 expression

1
1. scibot 09 Mar 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.isci.2023.106221
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9985040/
Feb 2023
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The Staphylococcus aureus protein IsdA increases SARS CoV-2 replication by modulating JAK-STAT signaling

1
1. scibot 01 Feb 2023
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.isci.2023.105975
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9838083/
Oct 2022
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TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex

1
1. scibot 20 Oct 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.celrep.2022.111513
  
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sciencedirect.com/science/article/pii/S2211124722013638
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PARP1 inhibition enhances reactive oxygen species on gut microbiota

1
1. scibot 24 Aug 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1002/jcp.30861
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9805012/
Jul 2022
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Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice

1
1. scibot 13 Jul 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.celrep.2022.111062
  
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sciencedirect.com/science/article/pii/S2211124722008609
Jun 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Upregulation of Cell Division Cycle 20 Expression Alters the Morphology of Neuronal Dendritic Spines in the Nucleus Accumbens by Promoting FMRP Ubiquitination

1
1. scibot 28 Jun 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1111/jnc.15649
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15649
May 2022
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A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

1
1. scibot 27 May 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.cell.2022.04.030
  
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sciencedirect.com/science/article/pii/S0092867422005281
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A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination

1
1. scibot 25 May 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.molcel.2022.04.031
  
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sciencedirect.com/science/article/pii/S109727652200394X
Mar 2022
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Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer

1
1. scibot 18 Mar 2022
  
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  AB_2737399
  
  DOI: 10.1016/j.xcrm.2022.100561
  
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sciencedirect.com/science/article/pii/S2666379122000684
elifesciences.org elifesciences.org

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

1
1. scibot 11 Mar 2022
  
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  RRID:AB_2737399
  
  DOI: 10.7554/eLife.75827
  
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elifesciences.org/articles/75827
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An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase

1
1. scibot 02 Mar 2022
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.isci.2022.103813
  
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sciencedirect.com/science/article/pii/S2589004222000839
Oct 2021
link.springer.com link.springer.com

The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus

1
1. scibot 26 Oct 2021
  
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  DOI: 10.1007/s10735-021-10032-y
  
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link.springer.com/article/10.1007/s10735-021-10032-y
Jun 2021
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H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.

1
1. scibot 09 Jun 2021
  
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  AC004
  
  DOI: 10.1016/j.jbc.2021.100852
  
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sciencedirect.com/science/article/pii/S0021925821006505
May 2021
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Mouse totipotent stem cells captured and maintained through spliceosomal repression

1
1. scibot 15 May 2021
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.cell.2021.04.020
  
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sciencedirect.com/science/article/pii/S0092867421005006
Jan 2020
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High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2737399
  
  DOI: 10.1016/j.yexcr.2019.111740
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0014482719306238