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    Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts
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    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
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  4. May 2024
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    The Human Intermediate Prolactin Receptor I-tail Contributes Breast Oncogenesis by Targeting Ras/MAPK Pathway
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  6. 52.53.155.43 52.53.155.43
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  7. Apr 2024
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    Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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  10. Mar 2024
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    VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
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  12. Feb 2024
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    Transcription factor ZNF263 enhances EGFR-targeted therapeutic response and reduces residual disease in lung adenocarcinoma
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    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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  15. Dec 2023
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    IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects
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  17. Nov 2023
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    Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia
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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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  21. Oct 2023
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    Adipocyte Subpopulations Mediate Growth Hormone-induced Lipolysis and Glucose Tolerance in Male Mice
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    Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1
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  24. Sep 2023
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    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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  26. Jul 2023
  27. 52.53.155.43 52.53.155.43
    cd-22-0411-html.html
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  28. Jun 2023
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    N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  31. Mar 2023
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  33. Dec 2022
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    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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  35. Aug 2022
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    STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
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    Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
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    sciencedirect.com/science/article/pii/S2211124722009676
  38. May 2022
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    Irreversible FLT3 Inhibitor FF-10101 Is Active Against a Diversity of FLT3 Inhibitor Resistance Mechanisms
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  40. Apr 2022
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    GH action in prostate cancer cells promotes proliferation limits apoptosis and regulates cancer-related gene expression
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  42. Sep 2021
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    Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming
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  44. May 2021
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    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes
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    sciencedirect.com/science/article/pii/S2211124721004368
  46. Apr 2021
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    A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
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  48. Nov 2020
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    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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  50. Sep 2020
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    Prolactin enhances the proliferation of proliferative endometrial glandular cells and endometrial cancer cells
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      DOI: 10.1210/jendso/bvz029

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    academic.oup.com/jes/article/4/2/bvz029/5671714
  52. Jan 2020
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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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      DOI: 10.1016/j.ccell.2019.10.002

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    Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet
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      DOI: 10.1016/j.molcel.2019.10.007

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    sciencedirect.com/science/article/pii/S1097276519307671
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    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
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      DOI: 10.1016/j.ccell.2019.10.011

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    Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
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      DOI: 10.1016/j.cmet.2019.10.015

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    sciencedirect.com/science/article/pii/S1550413119306060
  57. Nov 2018
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    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
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