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Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system

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  DOI: 10.1016/j.isci.2025.113228
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12392329/
Aug 2025
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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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  DOI: 10.1016/j.devcel.2025.08.003
  
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sciencedirect.com/science/article/pii/S1534580725005039
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KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.08.003
  
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sciencedirect.com/science/article/pii/S1097276525006537
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Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.chembiol.2025.07.006
  
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sciencedirect.com/science/article/pii/S2451945625002296
Jul 2025
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α6GABAA receptor positive allosteric modulators targeting trigeminal ganglia for preventing and aborting chronic periorbital allodynia and cephalic pain in both sexes: A mechanistic and comparative preclinical study

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sciencedirect.com/science/article/pii/S0753332225005384
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Tumor-specific antigen delivery for T-cell therapy via a pH-sensitive peptide conjugate

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  DOI: 10.1158/1535-7163.MCT-23-0809
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695185/
Jun 2025
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Comprehensive two-dimensional primary hepatic stellate cell (HSC) membrane chromatography-based screening of anti-fibrotic components from Schisandra chinensis (Turcz.) Baill. and mechanistic insights into gomisin N against liver fibrosis

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  DOI: 10.1016/j.jep.2025.120067
  
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sciencedirect.com/science/article/pii/S0378874125007548
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GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer

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  DOI: 10.1016/j.celrep.2025.115774
  
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May 2025
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AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.99670
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12080999/
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Structural insights into the human system y+L amino acid transporter complex

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.str.2025.04.012
  
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sciencedirect.com/science/article/pii/S0969212625001467
Apr 2025
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Cannabinoid CB2 receptor controls chronic itch by regulating spinal microglial activation and synaptic transmission

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115559
  
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1-s2.0-S0016508525005426-main-html.html

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1. scibot 05 Apr 2025
  
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  DOI: 10.1053/j.gastro.2025.03.019
  
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52.53.155.43/417f7e11cf34a4a05dabce5f916b0d6ed71a75c4/1-s2.0-S0016508525005426-main-html.html
Jan 2025
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CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability

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1. scibot 09 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115135
  
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sciencedirect.com/science/article/pii/S2211124724014864
Dec 2024
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FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology

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1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.cmet.2024.11.001
  
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sciencedirect.com/science/article/pii/S1550413124004479
Nov 2024
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Rab11-Rab8 cascade dynamics in primary cilia and membrane tubules

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114955
  
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sciencedirect.com/science/article/pii/S2211124724013068
Sep 2024
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m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.040
  
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sciencedirect.com/science/article/pii/S0092867424009693
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Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ebiom.2024.105356
  
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sciencedirect.com/science/article/pii/S235239642400392X
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GRP94 Promotes Anoikis Resistance and Peritoneal Metastasis through YAP/TEAD1 pathway in Gastric Cancer

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110638
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11381759/
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Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114691
  
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sciencedirect.com/science/article/pii/S2211124724010428
Jul 2024
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Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

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  DOI: 10.1016/j.celrep.2024.114425
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00754-X
Jun 2024
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Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti

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  DOI: 10.1016/j.cmet.2024.04.020
  
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sciencedirect.com/science/article/pii/S1550413124001761
May 2024
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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

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1. scibot 31 May 2024
  
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  DOI: 10.1016/j.ccell.2024.05.006
  
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sciencedirect.com/science/article/pii/S1535610824001697
Mar 2024
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Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion

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1. scibot 28 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.114002
  
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TET2 Regulation of Alcoholic Fatty Liver via Srebp1 mRNA in Paraspeckles

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  DOI: 10.1016/j.isci.2024.109278
  
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sciencedirect.com/science/article/pii/S2589004224004991
Feb 2024
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Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis

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  DOI: 10.1016/j.celrep.2024.113846
  
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sciencedirect.com/science/article/pii/S2211124724001748
Jan 2024
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bqae003-html.html

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1. scibot 18 Jan 2024
  
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  DOI: 10.1210/endocr/bqae003
  
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  DOI: 10.1210/endocr/bqae003
  
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52.53.155.43/3f4688776682134a396d2c8a2f9e0c5f280fe62c/bqae003-html.html
Dec 2023
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Pravastatin promotes type 2 diabetes vascular calcification through activating intestinal Bacteroides fragilis to induce macrophage M1 polarization

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  DOI: 10.1111/1753-0407.13514
  
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onlinelibrary.wiley.com/doi/10.1111/1753-0407.13514
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Choroid plexus mast cells drive tumor-associated hydrocephalus

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  DOI: 10.1016/j.cell.2023.11.001
  
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sciencedirect.com/science/article/pii/S0092867423011820
Nov 2023
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Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation

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  DOI: 10.1016/j.isci.2023.108303
  
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sciencedirect.com/science/article/pii/S2589004223023805
Oct 2023
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Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.bioadv.2023.213652
  
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sciencedirect.com/science/article/pii/S2772950823003758
Aug 2023
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

A combination of 5/6-nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease

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1. scibot 28 Aug 2023
  
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  DOI: 10.1096/fba.2023-00045
  
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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fba.2023-00045
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Allyl isothiocyanate mitigates airway inflammation and constriction in a house dust mite-induced allergic asthma model via upregulation of tight junction proteins and the TRPA1 modulation

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1. scibot 27 Aug 2023
  
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  DOI: 10.1016/j.biopha.2023.115334
  
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sciencedirect.com/science/article/pii/S0753332223011253
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XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

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1. scibot 26 Aug 2023
  
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  DOI: 10.1126/sciadv.adg5211
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10438455/
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XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

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  DOI: 10.1126/sciadv.adg5211
  
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  DOI: 10.1126/sciadv.adg5211
  
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Jul 2023
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Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles

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Jun 2023
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

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May 2023
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PDZD8-mediated endoplasmic reticulum–mitochondria associations regulate sympathetic drive and blood pressure through the intervention of neuronal mitochondrial homeostasis in stress-induced hypertension

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Autoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production

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  DOI: 10.1038/s41416-022-01910-7
  
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Mar 2023
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LncRNA INPP5F ameliorates stress-induced hypertension via the miR-335/Cttn axis in rostral ventrolateral medulla

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  DOI: 10.1111/cns.14142
  
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Gomisin D alleviates liver fibrosis through targeting PDGFRβ in hepatic stellate cells

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STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice

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  DOI: 10.1210/endocr/bqac215
  
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Jan 2023
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BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency

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Nov 2022
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CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

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Generation of a homozygous P4HA2 knockout human embryonic stem cell line (FDCHDPe012-A) by CRISPR/Cas9 system

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Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR

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Aug 2022
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Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-α/IL-18 Expression in the Spinal Cord

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Jun 2022
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PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine

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May 2022
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Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

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The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures

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Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas

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ncbi.nlm.nih.gov/pmc/articles/PMC9102156/
Mar 2022
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Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

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Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

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Nov 2021
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Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

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BPS Publications

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  DOI: 10.1111/bph.15667
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15667
Sep 2021
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11βHSD2 efficacy in preventing transcriptional activation of the mineralocorticoid receptor by corticosterone

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Jun 2021
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Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data

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May 2021
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Valproic Acid Induces Autism-Like Synaptic and Behavioral Deficits by Disrupting Histone Acetylation of Prefrontal Cortex ALDH1A1 in Rats

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Mar 2021
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DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells

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Jan 2021
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Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium

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Nov 2020
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Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation

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Sep 2020
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Protocol for Site-Specific Photo-Crosslinking Proteomics to Identify Protein-Protein Interactions in Mammalian Cells

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SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

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Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade

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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

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  HRP-Conjugated GAPDH Antibody
  
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Jan 2020
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Generation of a DAPK1 knockout first (conditional ready) human embryonic stem cell line (ZSSYe001-A) by CRISPR-Cas9 technology

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Programmable RNA-Guided RNA Effector Proteins Built from Human Parts

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  DOI: 10.1016/j.cell.2019.05.049
  
  Resource: (Proteintech Cat# HRP-60004, RRID:AB_2737588)
  
  Curator: @Naa003
  
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  RRID:AB_2737588 RRIDCUR:Validated
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Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning

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  RRID:AB_2737588
  
  DOI: 10.1016/j.cels.2018.09.002
  
  Resource: (Proteintech Cat# HRP-60004, RRID:AB_2737588)
  
  Curator: @Jmenke
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.01.021
  
  Resource: (Proteintech Cat# HRP-60004, RRID:AB_2737588)
  
  Curator: @ethanbadger
  
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  RRID:AB_2737588 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319300445

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