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SDCBP competes with CBL to stabilize PES1 and promote c-Myc translation in ESCC tumorigenesis

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Sep 2026
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SERINC2-mediated phosphatidylserine remodeling activates protrusion-localized AXL signaling to promote brain metastasis

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Apoptosis inhibition reprograms alveolar myofibroblasts toward ductal myofibroblasts

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Aug 2026
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Targeting host lipogenesis with a diarylamide inhibitor disrupts SARS-CoV-2 replication

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Jun 2026
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Receptor and cell-type-specific mechanisms in mesocortical dopamine circuits gate chronic pain and comorbid anxiodepression

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SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism

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A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity

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CCL1-AMFR facilitates glioblastoma progression by modulating the crosstalk between glioma cells and tumor-associated macrophages

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Apr 2026
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Global profiling of nascent chain interactors reveals TRIM25 as a co-translational E3 ubiquitin ligase

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Mar 2026
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Molecular mechanism underlying the specific RNA recognition of mitochondrial helicase DDX28 and its critical role in mitoribosomal biogenesis

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Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation

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Feb 2026
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supplementary_tables_ioaf271-html.html

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Jan 2026
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AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy

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Clostridium scindens attenuates acute kidney injury by producing indole-3-acetic acid

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HMMR/RHAMM recruits SACK1D/FAM83D-CK1α complex at the mitotic spindle to control spindle alignment

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Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer

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FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer

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Dec 2025
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HMOX1 drives dihydroartemisinin-sensitized ferroptosis antagonized by mitochondrial fusion

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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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Oct 2025
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1-s2.0-S2589004225020425-main-html.html

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CKD-Induced Oxidative Twitch Muscle Atrophy Is Mediated by TGF-β

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CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis

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Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression

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Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system

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Aug 2025
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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1

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Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

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α6GABAA receptor positive allosteric modulators targeting trigeminal ganglia for preventing and aborting chronic periorbital allodynia and cephalic pain in both sexes: A mechanistic and comparative preclinical study

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Tumor-specific antigen delivery for T-cell therapy via a pH-sensitive peptide conjugate

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Jun 2025
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Comprehensive two-dimensional primary hepatic stellate cell (HSC) membrane chromatography-based screening of anti-fibrotic components from Schisandra chinensis (Turcz.) Baill. and mechanistic insights into gomisin N against liver fibrosis

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GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer

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May 2025
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AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism

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Structural insights into the human system y+L amino acid transporter complex

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Apr 2025
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Cannabinoid CB2 receptor controls chronic itch by regulating spinal microglial activation and synaptic transmission

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1-s2.0-S0016508525005426-main-html.html

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Jan 2025
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CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability

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  DOI: 10.1016/j.celrep.2024.115135
  
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Dec 2024
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FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology

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Nov 2024
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Rab11-Rab8 cascade dynamics in primary cilia and membrane tubules

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Sep 2024
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m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells

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Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer

1
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GRP94 Promotes Anoikis Resistance and Peritoneal Metastasis through YAP/TEAD1 pathway in Gastric Cancer

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Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia

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Jul 2024
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Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

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Jun 2024
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Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti

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May 2024
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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

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Mar 2024
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Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion

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TET2 Regulation of Alcoholic Fatty Liver via Srebp1 mRNA in Paraspeckles

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Feb 2024
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Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis

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Jan 2024
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bqae003-html.html

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Dec 2023
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Pravastatin promotes type 2 diabetes vascular calcification through activating intestinal Bacteroides fragilis to induce macrophage M1 polarization

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Choroid plexus mast cells drive tumor-associated hydrocephalus

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Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation

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Oct 2023
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Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling

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Aug 2023
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A combination of 5/6-nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease

1
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Allyl isothiocyanate mitigates airway inflammation and constriction in a house dust mite-induced allergic asthma model via upregulation of tight junction proteins and the TRPA1 modulation

1
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XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

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XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility

2
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Jul 2023
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Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles

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Jun 2023
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer

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May 2023
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PDZD8-mediated endoplasmic reticulum–mitochondria associations regulate sympathetic drive and blood pressure through the intervention of neuronal mitochondrial homeostasis in stress-induced hypertension

1
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Autoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production

1
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  DOI: 10.1038/s41416-022-01910-7
  
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Mar 2023
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LncRNA INPP5F ameliorates stress-induced hypertension via the miR-335/Cttn axis in rostral ventrolateral medulla

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Feb 2023
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Gomisin D alleviates liver fibrosis through targeting PDGFRβ in hepatic stellate cells

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STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice

1
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  DOI: 10.1210/endocr/bqac215
  
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academic.oup.com/endo/article/164/3/bqac215/6967061
Jan 2023
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BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency

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Nov 2022
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CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

1
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Sep 2022
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Generation of a homozygous P4HA2 knockout human embryonic stem cell line (FDCHDPe012-A) by CRISPR/Cas9 system

1
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  DOI: 10.1016/j.scr.2022.102930
  
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Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR

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Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-α/IL-18 Expression in the Spinal Cord

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  DOI: 10.1007/s10571-022-01267-8
  
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Jun 2022
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PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine

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Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma

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  DOI: 10.1158/0008-5472.CAN-21-0810
  
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The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures

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  DOI: 10.3390/ijms23094964
  
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Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas

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  DOI: 10.3390/cells11091589
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9102156/
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Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

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  DOI: 10.4103/1673-5374.335165
  
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CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH

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  DOI: 10.1016/j.celrep.2022.110493
  
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Feb 2022
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Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

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  DOI: 10.1016/j.celrep.2022.110414
  
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sciencedirect.com/science/article/pii/S2211124722001383
Nov 2021
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Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

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  RRID:AB_2737588
  
  DOI: 10.1210/endocr/bqab214
  
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BPS Publications

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  DOI: 10.1111/bph.15667
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15667
Sep 2021
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11βHSD2 efficacy in preventing transcriptional activation of the mineralocorticoid receptor by corticosterone

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  DOI: 10.1210/jendso/bvab146
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8459447/
Jun 2021
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Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data

1
1. scibot 22 Jun 2021
  
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  HRP-60,004
  
  DOI: 10.1016/j.ebiom.2021.103436
  
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May 2021
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Valproic Acid Induces Autism-Like Synaptic and Behavioral Deficits by Disrupting Histone Acetylation of Prefrontal Cortex ALDH1A1 in Rats

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1. scibot 14 May 2021
  
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  DOI: 10.3389/fnins.2021.641284
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8113628/
Mar 2021
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DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells

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  DOI: 10.1007/s11064-021-03273-6
  
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link.springer.com/article/10.1007/s11064-021-03273-6
Jan 2021
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Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium

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  DOI: 10.7554/eLife.54618
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7817173/
Nov 2020
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Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation

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  DOI: 10.1016/j.molcel.2020.09.022
  
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sciencedirect.com/science/article/pii/S1097276520306523
Sep 2020
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Protocol for Site-Specific Photo-Crosslinking Proteomics to Identify Protein-Protein Interactions in Mammalian Cells

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  DOI: 10.1016/j.xpro.2020.100109
  
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SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

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Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade

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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

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  HRP-Conjugated GAPDH Antibody
  
  DOI: 10.1016/j.cell.2020.02.015
  
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Jan 2020
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Generation of a DAPK1 knockout first (conditional ready) human embryonic stem cell line (ZSSYe001-A) by CRISPR-Cas9 technology

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  DOI: 10.1016/j.scr.2019.101693
  
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Programmable RNA-Guided RNA Effector Proteins Built from Human Parts

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  DOI: 10.1016/j.cell.2019.05.049
  
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Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning

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  DOI: 10.1016/j.cels.2018.09.002
  
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CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis

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  DOI: 10.1016/j.immuni.2019.01.021
  
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sciencedirect.com/science/article/pii/S1074761319300445

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