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DF6215, an α-optimized IL-2-Fc fusion, expands immune effectors and drives robust preclinical anti-tumor activity

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1. scibot 09 Jan 2026
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.xcrm.2025.102518
  
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sciencedirect.com/science/article/pii/S2666379125005919
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis

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1. scibot 23 Dec 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1073/pnas.2519141122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12718373/
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
May 2025
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Dietary lipid overload creates a suppressive environment that impedes the antiviral functions of NK cells

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1. scibot 18 May 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.isci.2025.112396
  
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sciencedirect.com/science/article/pii/S2589004225006571
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Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies

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1. scibot 17 May 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.immuni.2025.03.021
  
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sciencedirect.com/science/article/pii/S1074761325001621
Apr 2025
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Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy

1
1. scibot 08 Apr 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.cmet.2025.03.003
  
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sciencedirect.com/science/article/pii/S1550413125001068
Mar 2025
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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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1. scibot 07 Mar 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.ccell.2025.02.017
  
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sciencedirect.com/science/article/pii/S1535610825000698
Jan 2025
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Regulatory T cell therapy is associated with distinct immune regulatory lymphocytic infiltrates in kidney transplants

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1. scibot 03 Jan 2025
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.medj.2024.11.014
  
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sciencedirect.com/science/article/pii/S2666634024004550
Aug 2024
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Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

1
1. scibot 30 Aug 2024
  
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  AB_2738577
  
  DOI: 10.1016/j.ccell.2024.08.007
  
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sciencedirect.com/science/article/pii/S1535610824003064
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Interleukin-2 immunotherapy reveals human regulatory T cell subsets with distinct functional and tissue-homing characteristics

1
1. scibot 21 Aug 2024
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.immuni.2024.07.016
  
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sciencedirect.com/science/article/pii/S1074761324003650
Jun 2024
www.cell.com www.cell.com

An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity

1
1. scibot 30 Jun 2024
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.isci.2024.110131
  
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cell.com/iscience/abstract/S2589-0042(24)01356-7
Apr 2024
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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

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1. scibot 24 Apr 2024
  
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  AB_2738577
  
  DOI: 10.1016/j.celrep.2024.114141
  
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sciencedirect.com/science/article/pii/S2211124724004698
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nanosphere pharmacodynamics improves safety of immunostimulatory cytokine therapy

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1. scibot 03 Feb 2024
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.isci.2024.108836
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10831265/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism

1
1. scibot 16 May 2023
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.isci.2023.106683
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Antitumor immunity induced by antibody-based natural killer cell engager therapeutics armed with not-alpha IL-2 variant

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1. scibot 27 Oct 2022
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.xcrm.2022.100783
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9589122/
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Defining HPV-specific B cell responses in head and neck cancer patients

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1. scibot 21 Sep 2022
  
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  AB_2738577
  
  DOI: 10.1038/s41586-020-2931-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9462833/
May 2022
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Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

1
1. scibot 12 May 2022
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.celrep.2022.110766
  
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sciencedirect.com/science/article/pii/S2211124722005307
Dec 2021
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The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

1
1. scibot 09 Dec 2021
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.xcrm.2021.100464
  
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sciencedirect.com/science/article/pii/S2666379121003360
Jul 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

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1. scibot 31 Jul 2021
  
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  anti-Ki-67 antibody
  
  DOI: 10.1016/j.immuni.2019.11.002
  
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  RRID:AB_2738577 RRIDCUR:Missing
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pmc.ncbi.nlm.nih.gov/articles/PMC6920571/
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.11.029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7682481/
Dec 2020
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Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection

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1. scibot 23 Dec 2020
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.xcrm.2020.100157
  
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  RRID:AB_2738577 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666379120302044
Sep 2020
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Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy

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1. scibot 03 Sep 2020
  
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  RRID:AB_2738577
  
  DOI: 10.1016/j.celrep.2020.107991
  
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  RRID:AB_2738577 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720309761