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Targeting PAR-2 with a negative allosteric modulator increases tumor antigen presentation and potentiates anti-PD-1 immunotherapy

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  DOI: 10.1136/jitc-2025-013507
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13052617/
Feb 2026
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MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species

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  DOI: 10.1016/j.immuni.2026.01.012
  
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sciencedirect.com/science/article/pii/S1074761326000336
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Eos plays a critical role in Treg homeostasis and modulates the function of recirculating thymic Tregs in the control of Treg development

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  DOI: 10.1016/j.celrep.2025.116838
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12869356/
Oct 2025
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Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116470
  
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sciencedirect.com/science/article/pii/S2211124725012410
Sep 2025
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CD226 identifies effector CD8+ T cells during tuberculosis and costimulates recognition of Mycobacterium tuberculosis-infected macrophages

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  DOI: 10.1016/j.celrep.2025.116184
  
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sciencedirect.com/science/article/pii/S2211124725009556
Jul 2025
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Naturalized immune responses are stable over years in a colony of laboratory mice with wild-derived microbiota

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.07.004
  
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sciencedirect.com/science/article/pii/S1074761325003139
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Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.018
  
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β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury

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1. scibot 10 Jul 2025
  
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  DOI: 10.7554/eLife.102068
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12237401/
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
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Macrophages direct location-dependent recall of B cell memory to vaccination

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.005
  
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sciencedirect.com/science/article/pii/S0092867425004076
Apr 2025
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1. scibot 02 Apr 2025
  
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  DOI: 10.1101/2025.03.25.645229
  
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52.53.155.43/ffe78fc87ac98471413371f69757651fb2a5b49c/PDF-html.html
Mar 2025
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Dynamic Tracking of Tumor Microenvironment Modulation Using Kaede Photoconvertible Transgenic Mice Unveils New Biological Properties of Viral Immunotherapy

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1. scibot 01 Mar 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0434
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831061/
Sep 2024
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Notch signaling regulates macrophage-mediated inflammation in metabolic dysfunction-associated steatotic liver disease

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.immuni.2024.08.016
  
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sciencedirect.com/science/article/pii/S107476132400414X
Aug 2024
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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114632
  
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sciencedirect.com/science/article/pii/S2211124724009823
Jul 2024
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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.chom.2024.06.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
Mar 2024
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CLEC-1 Restrains Acute Inflammatory Response and Recruitment of Neutrophils following Tissue Injury

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1. scibot 30 Mar 2024
  
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  DOI: 10.4049/jimmunol.2300479
  
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dx.doi.org/10.4049/jimmunol.2300479
Feb 2024
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Downregulation of IRF8 in alveolar macrophages by G-CSF promotes metastatic tumor progression

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1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109187
  
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sciencedirect.com/science/article/pii/S2589004224004085
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Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity

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1. scibot 07 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.002
  
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sciencedirect.com/science/article/pii/S107476132400027X
Nov 2023
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Germinal centers output clonally diverse plasma cell populations expressing high- and low-affinity antibodies

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1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.cell.2023.10.022
  
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sciencedirect.com/science/article/pii/S009286742301173X
Oct 2023
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Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

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1. scibot 20 Oct 2023
  
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  DOI: 10.1101/2023.09.04.556230
  
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52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
Sep 2023
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Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma

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1. scibot 28 Sep 2023
  
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  DOI: 10.1016/j.xcrm.2023.101188
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10518627/
Jul 2023
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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112814
  
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sciencedirect.com/science/article/pii/S2211124723008252
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Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin

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  DOI: 10.1016/j.immuni.2023.06.006
  
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TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

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1. scibot 01 Jul 2023
  
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  DOI: 10.1016/j.immuni.2023.06.007
  
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sciencedirect.com/science/article/pii/S1074761323002649
Apr 2023
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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

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  DOI: 10.1016/j.ccell.2023.03.019
  
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sciencedirect.com/science/article/pii/S1535610823000922
Mar 2023
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HSC-independent definitive hematopoiesis persists into adult life

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  DOI: 10.1016/j.celrep.2023.112239
  
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Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation

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  DOI: 10.1096/fj.202201469R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201469R
Jan 2023
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An evolved AAV variant enables efficient genetic engineering of murine T cells

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  DOI: 10.1016/j.cell.2022.12.022
  
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sciencedirect.com/science/article/pii/S0092867422015355
Nov 2022
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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

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1. scibot 29 Nov 2022
  
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  DOI: 10.1016/j.immuni.2022.11.001
  
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sciencedirect.com/science/article/pii/S107476132200591X
Jul 2022
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Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

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  DOI: 10.1016/j.cmet.2022.06.008
  
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cell.com/cell-metabolism/fulltext/S1550-4131(22)00228-5
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IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

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  DOI: 10.1016/j.immuni.2022.06.006
  
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sciencedirect.com/science/article/pii/S1074761322002795
Jun 2022
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Langerhans cells are an essential cellular intermediary in chronic dermatitis

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  DOI: 10.1016/j.celrep.2022.110922
  
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sciencedirect.com/science/article/pii/S2211124722006994
Apr 2022
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Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation

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1. scibot 07 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.005
  
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sciencedirect.com/science/article/pii/S1074761322001285
Mar 2022
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Mucus sialylation determines intestinal host-commensal homeostasis

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  DOI: 10.1016/j.cell.2022.02.013
  
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sciencedirect.com/science/article/pii/S0092867422001933
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Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer

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1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110485
  
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sciencedirect.com/science/article/pii/S2211124722002182
Jan 2022
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Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36

1
1. scibot 22 Jan 2022
  
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  RRID:AB_2738867
  
  DOI: 10.1096/fj.202101034R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101034R
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Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint

1
1. scibot 19 Jan 2022
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.celrep.2021.110259
  
  Resource: (BD Biosciences Cat# 564616, RRID:AB_2738867)
  
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sciencedirect.com/science/article/pii/S221112472101771X
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

1
1. scibot 01 Dec 2021
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.isci.2021.103387
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8605340/
May 2021
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

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1. scibot 07 May 2021
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.immuni.2020.09.006
  
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sciencedirect.com/science/article/pii/S1074761320304003
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HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis

1
1. scibot 03 May 2021
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.stem.2021.02.008
  
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sciencedirect.com/science/article/pii/S1934590921000588
Apr 2021
www.cell.com www.cell.com

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

1
1. scibot 24 Apr 2021
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.cell.2020.11.009
  
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cell.com/cell/fulltext/S0092-8674(20)31526-9
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Positive selection of IgG+ over IgM+ B cells in the germinal center reaction

1
1. scibot 15 Apr 2021
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.immuni.2021.03.013
  
  Resource: (BD Biosciences Cat# 564616, RRID:AB_2738867)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S1074761321001254
Sep 2020
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

1
1. scibot 26 Sep 2020
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.celrep.2020.01.099
  
  Resource: (BD Biosciences Cat# 564616, RRID:AB_2738867)
  
  Curator: @ethanbadger
  
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  RRID:AB_2738867 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720301339
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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.immuni.2020.01.014
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_2738867
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sciencedirect.com/science/article/pii/S107476132030042X
Jan 2020
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miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.celrep.2019.07.064
  
  Resource: (BD Biosciences Cat# 564616, RRID:AB_2738867)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719309684
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Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2738867
  
  DOI: 10.1016/j.cell.2019.08.009
  
  Resource: (BD Biosciences Cat# 564616, RRID:AB_2738867)
  
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  RRID:AB_2738867 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419308979
Nov 2018
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Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

1
1. scibot 05 Nov 2018
  
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  564616
  
  Curator: @Jmenke
  
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  RRID:AB_2738867 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S107476131830431X