17 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
    1
    1. scibot 02 Oct 2024
      AB_2744524

      DOI: 10.1016/j.xcrm.2024.101752

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    sciencedirect.com/science/article/pii/S2666379124004828
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
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    1. scibot 19 Aug 2024
      AB_2744524

      DOI: 10.1016/j.immuni.2024.07.010

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    sciencedirect.com/science/article/pii/S1074761324003595
  5. Jul 2024
  6. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
    1
    1. scibot 24 Jul 2024
      AB_2744524

      DOI: 10.1016/j.ccell.2024.05.026

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    sciencedirect.com/science/article/pii/S1535610824002174
  7. May 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deciphering the TET3 interactome in primary thymic developing T cells
    1
    1. scibot 09 May 2024
      RRID:AB_2744524

      DOI: 10.1016/j.isci.2024.109782

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    ncbi.nlm.nih.gov/pmc/articles/PMC11070343/
  9. Dec 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
    1
    1. scibot 22 Dec 2023
      RRID:AB_2744524

      DOI: 10.1038/s41467-023-43614-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730884/
  11. Mar 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
    1
    1. scibot 10 Mar 2023
      RRID:AB_2744524

      DOI: 10.1016/j.ccell.2023.02.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  13. Jun 2022
  14. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
    1
    1. scibot 22 Jun 2022
      RRID:AB_2744524

      DOI: 10.1016/j.chembiol.2022.05.012

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    sciencedirect.com/science/article/pii/S2451945622002045
  15. Mar 2022
  16. www.nature.com www.nature.com
    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
    1
    1. scibot 05 Mar 2022
      RRID:AB_2744524

      DOI: 10.1038/s41467-022-28515-1

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    nature.com/articles/s41467-022-28515-1
  17. Jul 2021
  18. elifesciences.org elifesciences.org
    Untitled document
    1
    1. scibot 27 Jul 2021
      RRID:AB_2744524

      DOI: 10.7554/eLife.40958

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    elifesciences.org/articles/40958
  19. Feb 2021
  20. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
    1
    1. scibot 28 Feb 2021
      RRID:AB_2744524

      DOI: 10.1016/j.chembiol.2020.12.004

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    sciencedirect.com/science/article/pii/S2451945620305134
  21. Jan 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Evaluation of the binding affinity of E3 ubiquitin ligase ligands by cellular target engagement and in-cell ELISA assay
    1
    1. scibot 26 Jan 2021
      RRID:AB_2744524

      DOI: 10.1016/j.xpro.2020.100288

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    sciencedirect.com/science/article/pii/S2666166720302756
  23. Sep 2020
  24. www.sciencedirect.com www.sciencedirect.com
    A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders
    1
    1. scibot 23 Sep 2020
      RRID:AB_2744524

      DOI: 10.1016/j.chembiol.2020.04.008

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    sciencedirect.com/science/article/pii/S2451945620301458
  25. Jan 2020
  26. www.sciencedirect.com www.sciencedirect.com
    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
    1
    1. scibot 13 Jan 2020
      RRID:AB_2744524

      DOI: 10.1016/j.chembiol.2019.11.014

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2451945619303964
  27. www.sciencedirect.com www.sciencedirect.com
    Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2744524

      DOI: 10.1016/j.celrep.2019.11.039

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    sciencedirect.com/science/article/pii/S2211124719315219
  28. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
    1
    1. scibot 13 Jan 2020
      RRID:AB_2744524

      DOI: 10.1016/j.ccell.2019.10.002

      Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610819304763
  29. www.sciencedirect.com www.sciencedirect.com
    Development and Characterization of a Wee1 Kinase Degrader
    1
    1. scibot 13 Jan 2020
      RRID:AB_2744524

      DOI: 10.1016/j.chembiol.2019.10.013

      Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)

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    sciencedirect.com/science/article/pii/S2451945619303587
  30. Nov 2018
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2744524

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    ncbi.nlm.nih.gov/pmc/articles/PMC6185104/