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Oct 2024
www.sciencedirect.com www.sciencedirect.com

Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition

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1. scibot 02 Oct 2024
  
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  AB_2744524
  
  DOI: 10.1016/j.xcrm.2024.101752
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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sciencedirect.com/science/article/pii/S2666379124004828
Aug 2024
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

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1. scibot 19 Aug 2024
  
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  AB_2744524
  
  DOI: 10.1016/j.immuni.2024.07.010
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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sciencedirect.com/science/article/pii/S1074761324003595
Jul 2024
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IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

1
1. scibot 24 Jul 2024
  
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  AB_2744524
  
  DOI: 10.1016/j.ccell.2024.05.026
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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sciencedirect.com/science/article/pii/S1535610824002174
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deciphering the TET3 interactome in primary thymic developing T cells

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1. scibot 09 May 2024
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.isci.2024.109782
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11070343/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery

1
1. scibot 22 Dec 2023
  
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  RRID:AB_2744524
  
  DOI: 10.1038/s41467-023-43614-3
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10730884/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

1
1. scibot 10 Mar 2023
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.ccell.2023.02.010
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
Jun 2022
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Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling

1
1. scibot 22 Jun 2022
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.chembiol.2022.05.012
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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sciencedirect.com/science/article/pii/S2451945622002045
Mar 2022
www.nature.com www.nature.com

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma

1
1. scibot 05 Mar 2022
  
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  RRID:AB_2744524
  
  DOI: 10.1038/s41467-022-28515-1
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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nature.com/articles/s41467-022-28515-1
Jul 2021
elifesciences.org elifesciences.org

Untitled document

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1. scibot 27 Jul 2021
  
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  RRID:AB_2744524
  
  DOI: 10.7554/eLife.40958
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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elifesciences.org/articles/40958
Feb 2021
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Targeted degradation of the enhancer lysine acetyltransferases CBP and p300

1
1. scibot 28 Feb 2021
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.chembiol.2020.12.004
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
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sciencedirect.com/science/article/pii/S2451945620305134
Jan 2021
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Evaluation of the binding affinity of E3 ubiquitin ligase ligands by cellular target engagement and in-cell ELISA assay

1
1. scibot 26 Jan 2021
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.xpro.2020.100288
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666166720302756
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.chembiol.2020.04.008
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945620301458
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.chembiol.2019.11.014
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619303964
www.sciencedirect.com www.sciencedirect.com

Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.celrep.2019.11.039
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719315219
www.sciencedirect.com www.sciencedirect.com

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.ccell.2019.10.002
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304763
www.sciencedirect.com www.sciencedirect.com

Development and Characterization of a Wee1 Kinase Degrader

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2744524
  
  DOI: 10.1016/j.chembiol.2019.10.013
  
  Resource: (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2744524
  
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  RRID:AB_2744524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619303587
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2744524
  
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  (Cell Signaling Technology Cat# 15103, RRID:AB_2744524)
  
  SciCrunch record: RRID:AB_2744524
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2744524
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RRID:AB_2744524

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ncbi.nlm.nih.gov/pmc/articles/PMC6185104/