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Oncogenic and tumor-suppressive forces converge on a progenitor niche at the benign-to-malignant transition

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.032
  
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sciencedirect.com/science/article/pii/S0092867426003338
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

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1. scibot 10 Feb 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0525
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12877752/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development

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1. scibot 18 Jun 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-4576
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 04 Apr 2025
  
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  DOI: 10.1158/0008-5472.can-24-4576
  
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52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

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1. scibot 11 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
Jan 2025
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Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex

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1. scibot 25 Jan 2025
  
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  DOI: 10.1038/s44318-024-00327-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11729872/
Dec 2024
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Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin

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1. scibot 14 Dec 2024
  
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  AB_2744683
  
  DOI: 10.1016/j.ccell.2024.11.013
  
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sciencedirect.com/science/article/pii/S1535610824004483
Aug 2024
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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114666
  
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sciencedirect.com/science/article/pii/S2211124724010179
May 2024
www.biorxiv.org www.biorxiv.org

SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer

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1. scibot 23 May 2024
  
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  AB_2744683
  
  DOI: 10.1101/2024.04.28.591518
  
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biorxiv.org/content/10.1101/2024.04.28.591518v1
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Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.neuron.2024.04.006
  
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sciencedirect.com/science/article/pii/S0896627324002447
Sep 2023
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Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

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1. scibot 29 Sep 2023
  
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  AB_2744683
  
  DOI: 10.1016/j.stem.2023.07.002
  
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sciencedirect.com/science/article/pii/S1934590923002473
Mar 2023
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In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity

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1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112216
  
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sciencedirect.com/science/article/pii/S2211124723002279
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

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1. scibot 10 Feb 2023
  
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  AB_2744683
  
  DOI: 10.3389/fnagi.2022.1095801
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9902592/
Oct 2022
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Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival

1
1. scibot 05 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111435
  
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sciencedirect.com/science/article/pii/S2211124722012761
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer

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1. scibot 07 Jun 2022
  
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  DOI: 10.1158/2159-8290.CD-21-0209
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7612573/
Dec 2021
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Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

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1. scibot 08 Dec 2021
  
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  RRID:AB_2744683
  
  DOI: 10.1016/j.celrep.2021.110099
  
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sciencedirect.com/science/article/pii/S221112472101593X
Aug 2021
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Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations

1
1. scibot 09 Aug 2021
  
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  AB_2744683
  
  DOI: 10.1016/j.neuron.2018.10.044
  
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sciencedirect.com/science/article/pii/S0896627318309528
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 30 Jul 2021
  
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  RRID:AB_2744683
  
  DOI: 10.1016/j.celrep.2019.03.104
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6486482/
May 2021
link.springer.com link.springer.com

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

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1. scibot 22 May 2021
  
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  DOI: 10.1186/s40478-021-01200-y
  
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link.springer.com/article/10.1186/s40478-021-01200-y
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An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53

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1. scibot 11 May 2021
  
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  DOI: 10.1016/j.devcel.2021.03.011
  
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sciencedirect.com/science/article/pii/S1534580721002082
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

Cell of Origin Influences Pancreatic Cancer Subtype

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1. scibot 10 May 2021
  
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  DOI: 10.1158/2159-8290.CD-20-0633
  
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cancerdiscovery.aacrjournals.org/content/11/3/660
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Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly

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1. scibot 08 May 2021
  
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  DOI: 10.1016/j.neuron.2020.10.035
  
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sciencedirect.com/science/article/pii/S089662732030859X
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.12.025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7886018/
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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

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1. scibot 17 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.05.010
  
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  RRID:AB_2744683 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820302609
Feb 2021
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Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.ccell.2020.11.013
  
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sciencedirect.com/science/article/pii/S153561082030605X
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Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

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1. scibot 11 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108726
  
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sciencedirect.com/science/article/pii/S2211124721000395
Jan 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair‐deficient mice

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1. scibot 26 Jan 2021
  
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  DOI: 10.1111/acel.13302
  
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onlinelibrary.wiley.com/doi/full/10.1111/acel.13302
Sep 2020
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p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.molcel.2019.12.014
  
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sciencedirect.com/science/article/pii/S109727651930927X
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Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers

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1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.stem.2020.01.009
  
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sciencedirect.com/science/article/pii/S1934590920300096
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.104
  
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sciencedirect.com/science/article/pii/S2211124719304516