92 Matching Annotations
  1. Jan 2026
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    PDCD5 promotes substrate release from the TRiC complex in cilia and flagella
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    sciencedirect.com/science/article/pii/S1097276525009864
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    Uromodulin alleviates fibrosis in acute kidney injury to chronic kidney disease transition by reducing EGFR
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    link.springer.com/article/10.1186/s12964-025-02537-w
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    A CLOCK-targeting lncRNA induces trained immunity against tuberculosis
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    sciencedirect.com/science/article/pii/S1931312825005219
  5. Nov 2025
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    WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair
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    sciencedirect.com/science/article/pii/S2211124725012914
  7. Oct 2025
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    Vitamin C conveys geroprotection on primate ovaries
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    sciencedirect.com/science/article/pii/S193459092500339X
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    Astragalin rescues Cadmium-induced cognitive decline by revering glial metabolic reprogramming and neuroinflammation via the mTOR/HIF-1α axis
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    sciencedirect.com/science/article/pii/S0306452225010024
  10. Sep 2025
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    Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation
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    Protein-based classification reveals an immune-hot subtype in IDH mutant astrocytoma with worse prognosis
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    sciencedirect.com/science/article/pii/S1535610825003630
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    Trefoil factor 2 interacts with A4GNT to regulate inflammation to protect against pneumonia during influenza virus infection
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    sciencedirect.com/science/article/pii/S2589004225016311
  14. Aug 2025
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    The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi
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    sciencedirect.com/science/article/pii/S1534580725004484
  16. Jun 2025
  17. www.cell.com www.cell.com
    Systematic profiling reveals betaine as an exercise mimetic for geroprotection
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    cell.com/cell/fulltext/S0092-8674(25)00635-X
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    Senescence-resistant human mesenchymal progenitor cells counter aging in primates
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    sciencedirect.com/science/article/pii/S0092867425005719
  19. Apr 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Constructed transferrin receptor-targeted liposome for the delivery of fluvoxamine to improve prognosis in a traumatic brain injury mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12001850/
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    Constructed transferrin receptor-targeted liposome for the delivery of fluvoxamine to improve prognosis in a traumatic brain injury mouse model
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    tandfonline.com/doi/abs/10.1080/10717544.2025.2486840
  22. Jan 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741067/
  24. Dec 2024
  25. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
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    nature.com/articles/s41419-024-07243-y
  26. Nov 2024
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    Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
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    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
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    LncRNA Snhg3 aggravates hepatic steatosis via PPARγ signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11495842/
  30. Oct 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433901/
  32. Sep 2024
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pharmacologic activation of activating transcription factor 6 contributes to neuronal survival after spinal cord injury in mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16092
  34. Aug 2024
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    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
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    sciencedirect.com/science/article/pii/S1550413124002821
  36. Jul 2024
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    Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity
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    Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer
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    The Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking
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    link.springer.com/article/10.1007/s12264-024-01236-9
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
  41. May 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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  43. Apr 2024
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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    sciencedirect.com/science/article/pii/S1097276524001369
  46. Feb 2024
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    ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation
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  48. Jan 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acute exposure of microwave impairs attention process by activating microglial inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10768366/
  51. Dec 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10687339/
  53. Oct 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    sciencedirect.com/science/article/pii/S1934590923003284
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bilirubin impacts microglial autophagy via the Akt–mTOR signaling pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15984
  56. 52.53.155.43 52.53.155.43
    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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  57. Sep 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and human
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  59. Aug 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Electroacupuncture attenuates myocardial ischemia-reperfusion injury by inhibiting microglial engulfment of dendritic spines
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  61. Jun 2023
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    Culture conditions of mouse ESCs impact the tumor appearance in vivo
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    Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/ Cas9 system
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serum response factor promotes axon regeneration following spinal cord transection injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233768/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233788/
  66. May 2023
  67. www.sciencedirect.com www.sciencedirect.com
    A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response
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  68. academic.oup.com academic.oup.com
    Circulating exosomes from patients with Graves’ disease induce an inflammatory immune response
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    academic.oup.com/endo/article/162/3/bqaa236/6046189
  69. Apr 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent hypoxia-induced enhancement of sociability and working memory associates with CNTNAP2 upregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10118049/
  71. Mar 2023
  72. europepmc.org europepmc.org
    UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS
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    europepmc.org/article/med/36943869
  73. Jan 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
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    ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
  75. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202200939RR
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    Resurrection of endogenous retroviruses during aging reinforces senescence
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  77. www.nature.com www.nature.com
    TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal
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    nature.com/articles/s41423-022-00963-1
  78. Dec 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative study of subcutaneous, intramuscular, and oral administration of bovine pathogenic Escherichia coli bacterial ghost vaccine in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9702981/
  80. Oct 2022
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC-mediated silencing of miR-181a-5p promotes pathogenic Th17 responses by modulating AKT3-FOXO3 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9557906/
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    Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation
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  83. journals.lww.com journals.lww.com
    Spliceosomal GTPase Eftud2 regulates microglial activation... : Neural Regeneration Research
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  84. Sep 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
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    ncbi.nlm.nih.gov/pmc/articles/PMC9481243/
  86. Aug 2022
  87. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Alterations of serine racemase expression determine proliferation and differentiation of neuroblastoma cells
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202200394RRR
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    Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism
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    Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-β oligomers
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15664
  90. Jul 2022
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    Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis
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  92. Jun 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
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    Nitric oxide improves regeneration and prevents calcification in bio-hybrid vascular grafts via regulation of vascular stem/progenitor cells
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    Maraviroc promotes recovery from traumatic brain injury in... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/01000/Maraviroc_promotes_recovery_from_traumatic_brain.33.aspx
  96. May 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage
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    ncbi.nlm.nih.gov/pmc/articles/PMC9083165/
  98. Mar 2022
  99. journals.lww.com journals.lww.com
    Bradykinin postconditioning protects rat hippocampal... : Neural Regeneration Research
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  100. journals.lww.com journals.lww.com
    SARM1 participates in axonal degeneration and mitochondrial ... : Neural Regeneration Research
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8848602/
  102. www.sciencedirect.com www.sciencedirect.com
    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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    sciencedirect.com/science/article/pii/S1097276522000855
  103. Feb 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8798967/
  105. Dec 2021
  106. www.sciencedirect.com www.sciencedirect.com
    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
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    sciencedirect.com/science/article/pii/S2211124721016533
  107. Oct 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Generation of SHMT2 knockout human embryonic stem cell line (WAe009-A-67) using CRISPR/Cas9 technique
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    sciencedirect.com/science/article/pii/S1873506121004281
  109. academic.oup.com academic.oup.com
    Differential effects of viral nucleic acid sensor signaling pathways on testicular Sertoli and Leydig cells
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    academic.oup.com/endo/article/162/12/bqab180/6359040
  110. academic.oup.com academic.oup.com
    Wnt5a Regulates Junctional Function of Sertoli cells Through PCP-Mediated Effects on mTORC1 and mTORC2
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    academic.oup.com/endo/article/162/10/bqab149/6334711
  111. Aug 2021
  112. www.sciencedirect.com www.sciencedirect.com
    Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance
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    sciencedirect.com/science/article/pii/S2211124721010457
  113. www.sciencedirect.com www.sciencedirect.com
    Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis
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    sciencedirect.com/science/article/pii/S1550413121003235
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation of Trans-active response DNA binding protein-of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15450
  115. Jul 2021
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic degradation of stromal interaction molecule 2 mediates disruption of neuronal dendrites by endoplasmic reticulum stress
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    onlinelibrary.wiley.com/doi/abs/10.1111/jnc.14712
  117. Mar 2021
  118. www.sciencedirect.com www.sciencedirect.com
    Generation of induced pluripotent stem cell line (IPTi002-A) from an 87-year old sporadic Alzheimer's disease patient with APOE3 (ε3/ε3) genotype
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    sciencedirect.com/science/article/pii/S1873506121001288
  119. Nov 2020
  120. www.sciencedirect.com www.sciencedirect.com
    Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex
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    sciencedirect.com/science/article/pii/S2211124720313310
  121. Sep 2020
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Thermostable mRNA Vaccine against COVID-19
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    ncbi.nlm.nih.gov/pmc/articles/PMC7377714/
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    Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells
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    OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature
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    sciencedirect.com/science/article/pii/S1534580720301933
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7462607/
  126. Jan 2020
  127. www.sciencedirect.com www.sciencedirect.com
    Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages
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