32 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2
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    1. scibot 17 Nov 2024
      RRID:AB_2749858

      DOI: 10.7554/eLife.98524

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    pmc.ncbi.nlm.nih.gov/articles/PMC11534337/
  3. Sep 2024
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy
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    1. scibot 27 Sep 2024
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      DOI: 10.1002/glia.24612

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    onlinelibrary.wiley.com/doi/10.1002/glia.24612
  5. Aug 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
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    1. scibot 21 Aug 2024
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      DOI: 10.1038/s41388-024-03094-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315672/
  7. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    1. scibot 13 Aug 2024
      Cell Signaling Cat# 83732

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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
  8. Jul 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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    1. scibot 27 Jul 2024
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      DOI: 10.1158/2767-9764.CRC-23-0428

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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
  10. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114433

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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  11. May 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Retron-Eco1 assembles NAD+-hydrolyzing filaments that provide immunity against bacteriophages
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    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1097276524003940
  13. Apr 2024
  14. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    1. scibot 18 Apr 2024
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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
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    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524002211
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.002

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      DOI: 10.1016/j.cell.2024.03.002

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    sciencedirect.com/science/article/pii/S0092867424002502
  17. Feb 2024
  18. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    1. scibot 22 Feb 2024
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      DOI: 10.1101/2023.09.27.559698

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    52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
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    Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113789

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    sciencedirect.com/science/article/pii/S2211124724001177
  20. Dec 2023
  21. www.sciencedirect.com www.sciencedirect.com
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113412

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    sciencedirect.com/science/article/pii/S2211124723014249
  22. Sep 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The interplay of TARG1 and PARG protects against genomic instability
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    1. scibot 12 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113113

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    sciencedirect.com/science/article/pii/S2211124723011245
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    PARP1 inhibition protects mice against Japanese encephalitis virus infection
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    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113103

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    sciencedirect.com/science/article/pii/S2211124723011142
  25. Jun 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Molecular basis for the reversible ADP-ribosylation of guanosine bases
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    1. scibot 30 Jun 2023
      RRID:AB_2749858

      DOI: 10.1016/j.molcel.2023.06.013

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    sciencedirect.com/science/article/pii/S1097276523004574
  27. Apr 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
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    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.molcel.2023.03.027

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    sciencedirect.com/science/article/pii/S109727652300240X
  29. Feb 2023
  30. www.sciencedirect.com www.sciencedirect.com
    PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1
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    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112060

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    sciencedirect.com/science/article/pii/S2211124723000712
  31. Dec 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
    1
    1. scibot 18 Dec 2022
      RRID:AB_2749858

      DOI: 10.1016/j.chembiol.2022.11.012

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    sciencedirect.com/science/article/pii/S2451945622004184
  33. link.springer.com link.springer.com
    A Simple Method to Study ADP-Ribosylation Reversal: From Function to Drug Discovery
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    1. scibot 17 Dec 2022
      RRID:AB_2749858

      DOI: 10.1007/978-1-0716-2891-1_8

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    link.springer.com/protocol/10.1007/978-1-0716-2891-1_8
  34. www.sciencedirect.com www.sciencedirect.com
    Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
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    1. scibot 11 Dec 2022
      RRID:AB_2749858

      DOI: 10.1016/j.chembiol.2022.11.006

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    sciencedirect.com/science/article/pii/S2451945622004123
  35. Oct 2022
  36. www.nature.com www.nature.com
    C9orf72 functions in the nucleus to regulate DNA damage repair
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    1. scibot 12 Oct 2022
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      DOI: 10.1038/s41418-022-01074-0

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    nature.com/articles/s41418-022-01074-0
  37. Jun 2022
  38. www.sciencedirect.com www.sciencedirect.com
    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110879

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    sciencedirect.com/science/article/pii/S2211124722006544
  39. Mar 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex
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    1. scibot 30 Mar 2022
      RRID:AB_2749858

      DOI: 10.1016/j.celrep.2022.110421

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    sciencedirect.com/science/article/pii/S2211124722001450
  41. Feb 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribose) drives condensation of FUS via a transient interaction
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    1. scibot 23 Feb 2022
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      DOI: 10.1016/j.molcel.2022.01.018

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    sciencedirect.com/science/article/pii/S1097276522000612
  43. Aug 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Gut microbiome ADP-ribosyltransferases are widespread phage-encoded fitness factors
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    1. scibot 17 Aug 2021
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      DOI: 10.1016/j.chom.2021.07.011

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    sciencedirect.com/science/article/pii/S1931312821003449
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
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    1. scibot 15 Aug 2021
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      DOI: 10.7554/eLife.59828

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    ncbi.nlm.nih.gov/pmc/articles/PMC8331182/
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity
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    1. scibot 27 Jul 2021
      RRID:AB_2749864

      DOI: 10.1016/j.chembiol.2018.09.011

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    sciencedirect.com/science/article/pii/S2451945618303313
  48. www.sciencedirect.com www.sciencedirect.com
    PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
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    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.ccell.2021.06.018

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    sciencedirect.com/science/article/pii/S1535610821003408
  49. Feb 2021
  50. elifesciences.org elifesciences.org
    Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
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    1. scibot 24 Feb 2021
      RRID:AB_2749858

      DOI: 10.7554/eLife.60480

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    elifesciences.org/articles/60480
  51. Jan 2021
  52. www.sciencedirect.com www.sciencedirect.com
    FOS licenses early events in stem cell activation driving skeletal muscle regeneration
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    1. scibot 27 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108656

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    sciencedirect.com/science/article/pii/S2211124720316454