14 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    1. scibot 14 Jul 2024
      RRID:AB_2750876

      DOI: 10.1016/j.isci.2024.110180

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC11238136/
  3. Jan 2024
  4. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    1. scibot 25 Jan 2024
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2023.12.039

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276523010857
  5. Mar 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition
    1
    1. scibot 29 Mar 2023
      RRID:AB_2750876

      DOI: 10.1158/2767-9764.CRC-22-0119

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    ncbi.nlm.nih.gov/pmc/articles/PMC10035383/
  7. Sep 2022
  8. www.sciencedirect.com www.sciencedirect.com
    Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells
    1
    1. scibot 13 Sep 2022
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2022.08.017

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276522008061
  9. Mar 2022
  10. www.sciencedirect.com www.sciencedirect.com
    RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
    1
    1. scibot 04 Mar 2022
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2022.01.025

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276522001010
  11. Dec 2021
  12. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis
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    1. scibot 29 Dec 2021
      AB_2750876

      DOI: 10.1016/j.celrep.2021.110146

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124721016429
  13. Jul 2021
  14. www.sciencedirect.com www.sciencedirect.com
    EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2
    1
    1. scibot 29 Jul 2021
      RRID: AB_2750876

      DOI: 10.1016/j.molcel.2019.05.026

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2750876

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    sciencedirect.com/science/article/pii/S1097276519303983
  15. Jun 2021
  16. www.sciencedirect.com www.sciencedirect.com
    RADX prevents genome instability by confining replication fork reversal to stalled forks
    1
    1. scibot 09 Jun 2021
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2021.05.014

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276521003907
  17. May 2021
  18. www.sciencedirect.com www.sciencedirect.com
    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
    1
    1. scibot 21 May 2021
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2021.04.028

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276521003579
  19. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
    1
    1. scibot 14 May 2021
      RRID:AB_2750876

      DOI: 10.1016/j.chom.2021.04.006

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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      SciCrunch record: RRID:AB_2750876

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    sciencedirect.com/science/article/pii/S1931312821001827
  20. Mar 2021
  21. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks
    1
    1. scibot 08 Mar 2021
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2020.10.009

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

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    sciencedirect.com/science/article/pii/S1097276520306924
  22. Oct 2020
  23. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
    1
    1. scibot 08 Oct 2020
      AB_2750876

      DOI: 10.1016/j.celrep.2020.108221

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2750876

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      RRID:AB_2750876 RRIDCUR:Validated
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    pubmed.ncbi.nlm.nih.gov/33027668/
  24. Sep 2020
  25. www.sciencedirect.com www.sciencedirect.com
    METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation
    1
    1. scibot 16 Sep 2020
      RRID:AB_2750876

      DOI: 10.1016/j.molcel.2020.06.017

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2750876

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      RRIDCUR:Validated RRID:AB_2750876
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    sciencedirect.com/science/article/pii/S1097276520304020
  26. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
    1
    1. scibot 05 Sep 2020
      RRID:AB_2750876

      DOI: 10.1016/j.celrep.2020.107974

      Resource: (Millipore Cat# OP92, RRID:AB_2750876)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2750876

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      RRIDCUR:Validated RRID:AB_2750876
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    sciencedirect.com/science/article/pii/S2211124720309554