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Protocol for extended-plex immunofluorescence staining of FFPE tissues using a sequential bleach-and-stain approach

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pmc.ncbi.nlm.nih.gov/articles/PMC13544394/
Jul 2026
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Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis

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Jan 2026
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Fibroblast-derived alarmin promotes oral wound healing by activating regulatory T cells that relay pro-angiogenic and anti-inflammatory responses

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Dec 2025
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1-s2.0-S2589004225026057-main-html.html

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Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12667737/
Sep 2025
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Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches

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Aug 2025
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Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis

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Clinical and molecular dissection of CAR T cell resistance in pancreatic cancer

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Jul 2025
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Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer

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Jun 2025
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Interferon-responsive HEVs drive tumor tertiary lymphoid structure formation and predict immunotherapy response in nasopharyngeal carcinoma

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PTEN protein phosphatase activity regulates metastasis by targeting PKCδ

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Apr 2025
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Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures

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Pre-existing skin-resident CD8 and γδ T cell circuits mediate immune response in Merkel cell carcinoma and predict immunotherapy efficacy

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1. scibot 02 Apr 2025
  
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  DOI: 10.1158/2159-8290.CD-23-0798
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11954000/
Feb 2025
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Distinct cellular mechanisms underlie chemotherapies and PD-L1 blockade combinations in triple-negative breast cancer

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Sep 2024
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Profound cellular defects attribute to muscular pathogenesis in the rhesus monkey model of Duchenne muscular dystrophy

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.041
  
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Aug 2024
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Multiplex Spatial Omics Reveals Changes in Immune-Epithelial Crosstalk During Inflammation and Dysplasia Development in Chronic IBD Patients

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1. scibot 21 Aug 2024
  
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May 2024
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Human ASXL1-mutant hematopoiesis is driven by a truncated protein associated with aberrant de-ubiquitination of H2AK119

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1. scibot 22 May 2024
  
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  DOI: 10.1158/2643-3230.BCD-23-0235
  
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aacrjournals.org/bloodcancerdiscov/article/5/3/202/745088/Human-ASXL1-Mutant-Hematopoiesis-Is-Driven-by-a
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Mapping the tumor stress network reveals dynamic shifts in the stromal oxidative stress response

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Dec 2023
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Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia

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Nov 2023
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Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

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Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma

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  DOI: 10.7554/eLife.80625
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
Oct 2023
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In vitro vascularized immunocompetent patient-derived model to test cancer therapies

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Sep 2023
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Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor induced colitis

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ncbi.nlm.nih.gov/pmc/articles/PMC10520880/
Jun 2023
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Spatially resolved multi-omics single-cell analyses inform mechanisms of immune-dysfunction in pancreatic cancer

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May 2023
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Intratumoral erythroblastic islands restrain anti-tumor immunity in hepatoblastoma

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Jan 2023
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Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver

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  DOI: 10.1016/j.phrs.2022.106643
  
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Nov 2022
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Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay

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  DOI: 10.1016/j.xpro.2022.101866
  
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Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

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Jun 2022
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A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation.

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Mar 2022
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T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation

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  DOI: 10.1016/j.xcrm.2022.100559
  
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Jan 2022
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Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions

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  DOI: 10.1016/j.crmeth.2021.100153
  
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Dec 2021
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MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data

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1. scibot 16 Dec 2021
  
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  DOI: 10.1016/j.xpro.2021.101034
  
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Oct 2021
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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

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1. scibot 20 Oct 2021
  
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  DOI: 10.1016/j.xcrm.2021.100419
  
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Jul 2021
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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

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1. scibot 01 Jul 2021
  
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  DOI: 10.1016/j.immuni.2021.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8188302/
Jun 2021
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Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity

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  RRID:AB_2750898
  
  DOI: 10.1016/j.cell.2021.05.013
  
  Resource: (Cell Signaling Technology Cat# 13917, RRID:AB_2750898)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2750898
  
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  RRID:AB_2750898
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RRID:AB_2750898

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scibot

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sciencedirect.com/science/article/pii/S0092867421006309
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_2750898
  
  DOI: 10.1016/j.ccell.2020.10.015
  
  Resource: (Cell Signaling Technology Cat# 13917, RRID:AB_2750898)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2750898
  
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  RRIDCUR:Validated RRID:AB_2750898
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RRID:AB_2750898

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S1535610820305468
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

1
1. scibot 27 Feb 2021
  
  in Public
  
  RRID:AB_2750898
  
  DOI: 10.1016/j.cell.2020.11.041
  
  Resource: (Cell Signaling Technology Cat# 13917, RRID:AB_2750898)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2750898
  
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  RRID:AB_2750898
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scibot

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sciencedirect.com/science/article/pii/S0092867420316135
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transferrin Receptor Is a Specific Ferroptosis Marker

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_2750898
  
  DOI: 10.1016/j.celrep.2020.02.049
  
  Resource: (Cell Signaling Technology Cat# 13917, RRID:AB_2750898)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2750898
  
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  RRID:AB_2750898 RRIDCUR:Validated
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RRID:AB_2750898

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7172030/