38 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
    1
    1. scibot 19 Aug 2024
      AB_2750916

      DOI: 10.1016/j.isci.2024.110499

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    sciencedirect.com/science/article/pii/S2589004224017243
  3. www.nature.com www.nature.com
    Table 2 Antibodies (for flow cytometry and immunoblotting assays).
    1
    1. scibot 02 Aug 2024
      Cas9

      DOI: 10.1038/s41598-021-82137-z

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    nature.com/articles/s41598-021-82137-z/tables/2
  4. Jul 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
    1
    1. scibot 31 Jul 2024
      RRID:AB_2750916

      DOI: 10.1158/2767-9764.CRC-24-0247

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    ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
  6. Jun 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-induced CTCF promotes EMT in breast cancer
    1
    1. scibot 21 Jun 2024
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2024.114367

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    sciencedirect.com/science/article/pii/S2211124724006958
  8. Apr 2024
  9. aacrjournals.org aacrjournals.org
    The chromatin remodeler CHD4 sustains Ewing Sarcoma cell survival by controlling global chromatin architecture
    1
    1. scibot 19 Apr 2024
      RRID:AB_2750916

      DOI: 10.1158/0008-5472.CAN-22-3950

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    aacrjournals.org/cancerres/article/84/2/241/733111/The-Chromatin-Remodeler-CHD4-Sustains-Ewing
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
    1
    1. scibot 03 Apr 2024
      RRID:AB_2750916

      DOI: 10.1016/j.xcrm.2024.101471

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983104/
  11. Mar 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense
    2
    1. scibot 01 Mar 2024
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2024.113849

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      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2024.113849

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    sciencedirect.com/science/article/pii/S2211124724001773
  13. Feb 2024
  14. 52.53.155.43 52.53.155.43
    241-html.html
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    1. scibot 23 Feb 2024
      AB_2750916

      DOI: 10.1158/0008-5472.can-22-3950

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    52.53.155.43/ef1c2343cba3a29438101d6931686796493196a8/241-html.html
  15. www.sciencedirect.com www.sciencedirect.com
    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
    2
    1. scibot 15 Feb 2024
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2024.113765

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    2. scibot 15 Feb 2024
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2024.113765

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    sciencedirect.com/science/article/pii/S2211124724000937
  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
    1
    1. scibot 22 Dec 2023
      AB_2750916

      DOI: 10.1038/s41467-023-43614-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730884/
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
    1
    1. scibot 28 Nov 2023
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2023.113434

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    sciencedirect.com/science/article/pii/S2211124723014468
  20. Apr 2023
  21. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
    1
    1. scibot 20 Apr 2023
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  22. www.sciencedirect.com www.sciencedirect.com
    A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
    1
    1. scibot 19 Apr 2023
      RRID:AB_2750916

      DOI: 10.1016/j.xcrm.2023.101015

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    sciencedirect.com/science/article/pii/S2666379123001258
  23. Nov 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
    1
    1. scibot 19 Nov 2022
      RRID:AB_2750916

      DOI: 10.1158/2767-9764.crc-22-0024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  25. Sep 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
    1
    1. scibot 22 Sep 2022
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2022.111363

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    sciencedirect.com/science/article/pii/S2211124722011950
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
    1. scibot 02 Sep 2022
      RRID:AB_2750916

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  28. Aug 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
    1
    1. scibot 17 Aug 2022
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2022.111181

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    sciencedirect.com/science/article/pii/S2211124722009949
  30. Jul 2022
  31. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
    1
    1. scibot 29 Jul 2022
      RRID:AB_2750916

      DOI: 10.1158/2767-9764.CRC-22-0024

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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  32. Mar 2022
  33. aacrjournals.org aacrjournals.org
    EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma
    1
    1. scibot 10 Mar 2022
      RRID:AB_2750916

      DOI: 10.1158/2159-8290.CD-21-0385

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    aacrjournals.org/cancerdiscovery/article/12/3/730/681918/EP300-Selectively-Controls-the-Enhancer-Landscape
  34. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
    1
    1. scibot 02 Mar 2022
      cell signalingAb #14697

      DOI: 10.1016/j.celrep.2022.110457

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    sciencedirect.com/science/article/pii/S221112472200184X
  35. Feb 2022
  36. www.sciencedirect.com www.sciencedirect.com
    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
    1
    1. scibot 23 Feb 2022
      RRID:AB_2750916

      DOI: 10.1016/j.molcel.2022.01.015

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    sciencedirect.com/science/article/pii/S1097276522000582
  37. Jan 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
    1
    1. scibot 12 Jan 2022
      RRID:AB_2750916

      DOI: 10.1016/j.cell.2021.12.021

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    sciencedirect.com/science/article/pii/S0092867421014847
  39. Nov 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
    1
    1. scibot 30 Nov 2021
      RRID:AB_2750916

      DOI: 10.1016/j.stem.2021.11.001

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    sciencedirect.com/science/article/pii/S1934590921004495
  41. Aug 2021
  42. www.sciencedirect.com www.sciencedirect.com
    A genotype-phenotype screening system using conditionally immortalized immature dendritic cells
    1
    1. scibot 13 Aug 2021
      Cat# 14697

      DOI: 10.1016/j.xpro.2021.100732

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    sciencedirect.com/science/article/pii/S2666166721004391
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Aug 2021
      RRID:AB_2750916

      DOI: 10.1186/s12915-018-0617-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC6309101/
  44. Jul 2021
  45. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
    1
    1. scibot 31 Jul 2021
      Anti-Cas9

      DOI: 10.1158/1541-7786.MCR-19-0747

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    mcr.aacrjournals.org/content/17/11/2208
  46. May 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Cas9 deactivation with photocleavable guide RNAs
    1
    1. scibot 08 May 2021
      RRID:AB_2750916

      DOI: 10.1016/j.molcel.2021.02.007

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    sciencedirect.com/science/article/pii/S1097276521000939
  48. Apr 2021
  49. www.sciencedirect.com www.sciencedirect.com
    A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression
    1
    1. scibot 24 Apr 2021
      RRID:AB_2750916

      DOI: 10.1016/j.cell.2020.12.017

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    sciencedirect.com/science/article/pii/S0092867420316871
  50. www.sciencedirect.com www.sciencedirect.com
    Generation of an ELTD1 knockout human embryonic stem cell line by the iCRISPR/Cas9 system
    1
    1. scibot 16 Apr 2021
      RRID:AB_2750916

      DOI: 10.1016/j.scr.2021.102350

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    sciencedirect.com/science/article/pii/S1873506121001963
  51. Sep 2020
  52. www.sciencedirect.com www.sciencedirect.com
    YAP-depleted iPSC MUSIi012-A-2 maintained all normal stem cell characteristics
    1
    1. scibot 16 Sep 2020
      AB_2750916

      DOI: 10.1016/j.scr.2020.101723

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    sciencedirect.com/science/article/pii/S1873506120300271
  53. elifesciences.org elifesciences.org
    NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
    1
    1. scibot 10 Sep 2020
      RRID:AB_2750916

      DOI: 10.7554/eLife.54993

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    elifesciences.org/articles/54993
  54. www.sciencedirect.com www.sciencedirect.com
    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection
    1
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      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2020.01.052

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    sciencedirect.com/science/article/pii/S2211124720300772
  55. Jan 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2750916

      DOI: 10.1016/j.ccell.2019.05.013

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    sciencedirect.com/science/article/pii/S1535610819302557
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    Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_2750916

      DOI: 10.1016/j.celrep.2019.11.065

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    sciencedirect.com/science/article/pii/S2211124719315566
  58. elifesciences.org elifesciences.org
    Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain
    1
    1. scibot 13 Jan 2020
      RRID:AB_2750916

      DOI: 10.7554/eLife.46500

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    elifesciences.org/articles/46500
  59. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
    1
    1. scibot 13 Jan 2020
      RRID:AB_2750916

      DOI: 10.1186/s12915-018-0617-1

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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0617-1