39 Matching Annotations
  1. Apr 2024
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    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
    1
    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524002211
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003723
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    DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability
    2
    1. scibot 04 Apr 2024
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    2. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524001886
  5. Feb 2024
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113778

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    sciencedirect.com/science/article/pii/S2211124724001062
  7. Sep 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1101/gad.350594.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
  9. Aug 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Small molecule targeting of transcription-replication conflict for selective chemotherapy
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    sciencedirect.com/science/article/pii/S2451945623002210
  11. Jul 2023
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    Protocol for automated multivariate quantitative-image-based cytometry analysis by fluorescence microscopy of asynchronous adherent cells
    1
    1. scibot 22 Jul 2023
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    sciencedirect.com/science/article/pii/S2666166723004136
  13. Apr 2023
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    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
    1
    1. scibot 22 Apr 2023
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    sciencedirect.com/science/article/pii/S2211124723003832
  15. Mar 2023
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    Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest
    1
    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112215

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    sciencedirect.com/science/article/pii/S2211124723002267
  17. Dec 2022
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    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
    1
    1. scibot 18 Dec 2022
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    sciencedirect.com/science/article/pii/S2211124722017119
  19. Nov 2022
  20. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    1
    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111716

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    sciencedirect.com/science/article/pii/S2211124722015947
  21. www.nature.com www.nature.com
    DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts
    1
    1. scibot 09 Nov 2022
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      DOI: 10.1038/s41388-022-02517-1

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    nature.com/articles/s41388-022-02517-1
  22. Sep 2022
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    Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
    1
    1. scibot 24 Sep 2022
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    sciencedirect.com/science/article/pii/S109727652200898X
  24. Aug 2022
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    Increasing cell size remodels the proteome and promotes senescence
    1
    1. scibot 22 Aug 2022
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      DOI: 10.1016/j.molcel.2022.07.017

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    sciencedirect.com/science/article/pii/S1097276522007134
  26. Jul 2022
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    Optimized protocol for isolation of germ cells from mouse testis by centrifugal elutriation
    1
    1. scibot 15 Jul 2022
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      DOI: 10.1016/j.xpro.2022.101540

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    sciencedirect.com/science/article/pii/S2666166722004208
  28. Mar 2022
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    BMI-1 regulates DNA end resection and homologous recombination repair
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110536

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    sciencedirect.com/science/article/pii/S2211124722002777
  30. Nov 2021
  31. academic.oup.com academic.oup.com
    Variations of C14ORF39 and SYCE1 identified in idiopathic premature ovarian insufficiency and nonobstructive azoospermia
    1
    1. scibot 25 Nov 2021
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      DOI: 10.1210/clinem/dgab777

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab777/6411788
  32. Sep 2021
  33. www.sciencedirect.com www.sciencedirect.com
    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
    1
    1. scibot 23 Sep 2021
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      DOI: 10.1016/j.molcel.2021.08.028

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    sciencedirect.com/science/article/pii/S109727652100695X
  34. Jun 2021
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    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
    1
    1. scibot 24 Jun 2021
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      DOI: 10.1016/j.molcel.2021.05.026

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    sciencedirect.com/science/article/pii/S109727652100410X
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
    1
    1. scibot 18 May 2021
      Anti phospho-H2AX (Ser139)

      DOI: 10.1016/j.devcel.2021.04.022

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    sciencedirect.com/science/article/pii/S1534580721003609
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    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
    1
    1. scibot 10 May 2021
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      DOI: 10.1016/j.cell.2021.04.016

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    sciencedirect.com/science/article/pii/S0092867421004955
  39. Apr 2021
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    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2020.11.004

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    sciencedirect.com/science/article/pii/S1535610820305961
  41. Mar 2021
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    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
    1
    1. scibot 03 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108808

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    sciencedirect.com/science/article/pii/S2211124721001224
  43. Feb 2021
  44. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
    1
    1. scibot 27 Feb 2021
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      DOI: 10.1016/j.cell.2020.11.042

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    sciencedirect.com/science/article/pii/S0092867420316147
  45. www.cell.com www.cell.com
    Nuclear Deformation Causes DNA Damage by Increasing Replication Stress
    1
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      DOI: 10.1016/j.cub.2020.11.037

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    cell.com/current-biology/abstract/S0960-9822(20)31748-6
  46. Jan 2021
  47. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
    1
    1. scibot 28 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108669

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    sciencedirect.com/science/article/pii/S2211124720316582
  48. link.springer.com link.springer.com
    Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
    1
    1. scibot 12 Jan 2021
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      DOI: 10.1186/s13046-020-01811-8

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    link.springer.com/article/10.1186/s13046-020-01811-8
  49. www.sciencedirect.com www.sciencedirect.com
    USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells
    1
    1. scibot 05 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108533

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    sciencedirect.com/science/article/pii/S2211124720315229
  50. Oct 2020
  51. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A guide to assessing cellular senescence in vitro and in vivo
    1
    1. scibot 22 Oct 2020
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      DOI: 10.1111/febs.15570

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.15570
  52. Sep 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107632

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    sciencedirect.com/science/article/pii/S2211124720305854
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    Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity
    1
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      DOI: 10.1016/j.cels.2020.07.004

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    sciencedirect.com/science/article/pii/S2405471220302477
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    Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells
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    1. scibot 15 Sep 2020
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      DOI: 10.1186/s13148-020-00839-z

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    link.springer.com/article/10.1186/s13148-020-00839-z
  56. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
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      DOI: 10.1016/j.cmet.2020.06.004

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    sciencedirect.com/science/article/pii/S1550413120303053
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
    1
    1. scibot 04 Sep 2020
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      DOI: 10.1016/j.celrep.2020.03.029

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    sciencedirect.com/science/article/pii/S2211124720303430
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
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    1. scibot 13 Jan 2020
      RRID:AB_2755003

      DOI: 10.1016/j.molcel.2019.06.023

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    sciencedirect.com/science/article/pii/S1097276519304794
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    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.10.008

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    sciencedirect.com/science/article/pii/S1097276519307683
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    Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.ccell.2019.09.004

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    sciencedirect.com/science/article/pii/S1535610819304246
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    Untitled document
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.devcel.2019.04.020

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    sciencedirect.com/science/article/pii/S153458071930317X