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Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

R-PLA enables enhanced detection of R-loops in mammalian cells using proximity ligation

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  DOI: 10.1016/j.crmeth.2026.101380
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13198002/
May 2026
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Non-centromeric CENP-A regulates epithelial-mesenchymal plasticity and heterogeneity in human cells

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  DOI: 10.1016/j.celrep.2026.117405
  
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sciencedirect.com/science/article/pii/S2211124726004833
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Gastric epithelium from BRCA1 and BRCA2 carriers harbors increased double-stranded DNA damage and enhanced growth potential

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  DOI: 10.1158/1541-7786.MCR-25-0970
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13110856/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RAD51-based homologous recombination deficiency is associated with treatment response and survival in early breast cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC13079792/
Mar 2026
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Overexpression of the ERG oncogene in prostate cancer identifies candidates for PARP inhibitor-based radiosensitization

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  DOI: 10.1172/JCI194949
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12987654/
Feb 2026
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Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability

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pmc.ncbi.nlm.nih.gov/articles/PMC12995521/
Jan 2026
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Cannabidiol does not cause DNA double-strand breaks in a human liver-derived cell model

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  DOI: 10.1186/s42238-025-00365-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12817681/
54.241.53.176 54.241.53.176

2026.01.21.700886v1.full-html.html

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54.241.53.176/bdd50a9018c213744bdf3c237d3ef5763deb458b/2026.01.21.700886v1.full-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever

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  DOI: 10.1038/s44321-025-00347-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12808722/
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5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation

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  DOI: 10.1016/j.xcrm.2025.102537
  
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sciencedirect.com/science/article/pii/S266637912500610X
Aug 2025
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A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.07.023
  
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sciencedirect.com/science/article/pii/S109727652500646X
rupress.org rupress.org

Origin of chromosome 12 trisomy surge in human induced pluripotent stem cells

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  DOI: 10.1083/jcb.202501231
  
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rupress.org/jcb/article/224/11/e202501231/278203/Origin-of-chromosome-12-trisomy-surge-in-human
Jul 2025
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A Bioequivalent Cornea Cross-linking Method using Photo-initiators LAP and Visible light

1
1. scibot 19 Jul 2025
  
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  DOI: 10.1016/j.mtbio.2025.102110
  
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sciencedirect.com/science/article/pii/S2590006425006805
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.011
  
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sciencedirect.com/science/article/pii/S1535610825002612
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Impact of High Adiposity on Endometrial Progesterone Response and Metallothionein Regulation

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1. scibot 19 Apr 2025
  
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  DOI: 10.1210/clinem/dgae236
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11479696/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks

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1. scibot 08 Mar 2025
  
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  DOI: 10.26508/lsa.202403074
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11884936/
Feb 2025
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Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors

1
1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.molcel.2025.01.031
  
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sciencedirect.com/science/article/pii/S109727652500098X
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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.molcel.2025.01.008
  
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sciencedirect.com/science/article/pii/S1097276525000425
Dec 2024
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PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115066
  
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sciencedirect.com/science/article/pii/S2211124724014177
Jul 2024
www.biorxiv.org www.biorxiv.org

MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks

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1. scibot 26 Jul 2024
  
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  DOI: 10.1101/2024.07.20.604390
  
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biorxiv.org/content/10.1101/2024.07.20.604390v1
Apr 2024
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BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response

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1. scibot 09 Apr 2024
  
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sciencedirect.com/science/article/pii/S1097276524002211
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A senescence restriction point acting on chromatin integrates oncogenic signals

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  DOI: 10.1016/j.celrep.2024.114044
  
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sciencedirect.com/science/article/pii/S2211124724003723
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DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability

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  DOI: 10.1016/j.molcel.2024.03.006
  
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sciencedirect.com/science/article/pii/S1097276524001886
Feb 2024
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SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability

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  DOI: 10.1016/j.celrep.2024.113778
  
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sciencedirect.com/science/article/pii/S2211124724001062
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histone bivalency regulates the timing of cerebellar granule cell development

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1. scibot 17 Sep 2023
  
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  DOI: 10.1101/gad.350594.123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
Aug 2023
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Small molecule targeting of transcription-replication conflict for selective chemotherapy

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  DOI: 10.1016/j.chembiol.2023.07.001
  
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sciencedirect.com/science/article/pii/S2451945623002210
Jul 2023
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Protocol for automated multivariate quantitative-image-based cytometry analysis by fluorescence microscopy of asynchronous adherent cells

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  DOI: 10.1016/j.xpro.2023.102446
  
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sciencedirect.com/science/article/pii/S2666166723004136
Apr 2023
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NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

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  DOI: 10.1016/j.celrep.2023.112372
  
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sciencedirect.com/science/article/pii/S2211124723003832
Mar 2023
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Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest

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  DOI: 10.1016/j.celrep.2023.112215
  
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sciencedirect.com/science/article/pii/S2211124723002267
Dec 2022
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The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response

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  DOI: 10.1016/j.celrep.2022.111819
  
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sciencedirect.com/science/article/pii/S2211124722017119
Nov 2022
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POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

1
1. scibot 18 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111716
  
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sciencedirect.com/science/article/pii/S2211124722015947
www.nature.com www.nature.com

DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts

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1. scibot 09 Nov 2022
  
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  DOI: 10.1038/s41388-022-02517-1
  
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nature.com/articles/s41388-022-02517-1
Sep 2022
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Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.molcel.2022.09.009
  
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sciencedirect.com/science/article/pii/S109727652200898X
Aug 2022
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Increasing cell size remodels the proteome and promotes senescence

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1. scibot 22 Aug 2022
  
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  DOI: 10.1016/j.molcel.2022.07.017
  
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sciencedirect.com/science/article/pii/S1097276522007134
Jul 2022
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Optimized protocol for isolation of germ cells from mouse testis by centrifugal elutriation

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1. scibot 15 Jul 2022
  
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  DOI: 10.1016/j.xpro.2022.101540
  
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sciencedirect.com/science/article/pii/S2666166722004208
Mar 2022
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BMI-1 regulates DNA end resection and homologous recombination repair

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  DOI: 10.1016/j.celrep.2022.110536
  
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Nov 2021
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Variations of C14ORF39 and SYCE1 identified in idiopathic premature ovarian insufficiency and nonobstructive azoospermia

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  DOI: 10.1210/clinem/dgab777
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab777/6411788
Sep 2021
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A hydride transfer complex reprograms NAD metabolism and bypasses senescence

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  DOI: 10.1016/j.molcel.2021.08.028
  
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sciencedirect.com/science/article/pii/S109727652100695X
Jun 2021
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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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  DOI: 10.1016/j.molcel.2021.05.026
  
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May 2021
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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness

1
1. scibot 18 May 2021
  
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  Anti phospho-H2AX (Ser139)
  
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

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  DOI: 10.1016/j.cell.2021.04.016
  
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sciencedirect.com/science/article/pii/S0092867421004955
Apr 2021
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MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

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  DOI: 10.1016/j.ccell.2020.11.004
  
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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

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  DOI: 10.1016/j.celrep.2021.108808
  
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sciencedirect.com/science/article/pii/S2211124721001224
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

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1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.cell.2020.11.042
  
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Nuclear Deformation Causes DNA Damage by Increasing Replication Stress

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  DOI: 10.1016/j.cub.2020.11.037
  
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cell.com/current-biology/fulltext/S0960-9822(20)31748-6
Jan 2021
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DCAF14 promotes stalled fork stability to maintain genome integrity

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  DOI: 10.1016/j.celrep.2020.108669
  
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jeccr.biomedcentral.com jeccr.biomedcentral.com

Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer

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  DOI: 10.1186/s13046-020-01811-8
  
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USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

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  DOI: 10.1016/j.celrep.2020.108533
  
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sciencedirect.com/science/article/pii/S2211124720315229
Oct 2020
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

A guide to assessing cellular senescence in vitro and in vivo

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  DOI: 10.1111/febs.15570
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.15570
Sep 2020
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Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis

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Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity

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  DOI: 10.1016/j.cels.2020.07.004
  
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Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells

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  DOI: 10.1186/s13148-020-00839-z
  
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Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage

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  DOI: 10.1016/j.cmet.2020.06.004
  
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Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

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  DOI: 10.1016/j.celrep.2020.03.029
  
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sciencedirect.com/science/article/pii/S2211124720303430
Jan 2020
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C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex

1
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  RRID:AB_2755003
  
  DOI: 10.1016/j.molcel.2019.06.023
  
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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

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  DOI: 10.1016/j.molcel.2019.10.008
  
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Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer

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  DOI: 10.1016/j.ccell.2019.09.004
  
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sciencedirect.com/science/article/pii/S1535610819304246
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Untitled document

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  DOI: 10.1016/j.devcel.2019.04.020
  
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sciencedirect.com/science/article/pii/S153458071930317X