30 Matching Annotations
  1. Dec 2023
  2. www.sciencedirect.com www.sciencedirect.com
    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
    1
    1. scibot 20 Dec 2023
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2023.113581

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    sciencedirect.com/science/article/pii/S2211124723015930
  3. www.sciencedirect.com www.sciencedirect.com
    ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation
    2
    1. scibot 17 Dec 2023
      RRID:AB_2755041

      DOI: 10.1016/j.molcel.2023.11.015

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    2. scibot 17 Dec 2023
      RRID:AB_2755041

      DOI: 10.1016/j.molcel.2023.11.015

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    sciencedirect.com/science/article/pii/S1097276523009607
  4. Jun 2023
  5. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine
    1
    1. scibot 21 Jun 2023
      RRID:AB_2755041

      DOI: 10.1016/j.cell.2023.05.027

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    sciencedirect.com/science/article/pii/S0092867423005779
  6. May 2023
  7. www.sciencedirect.com www.sciencedirect.com
    Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
    1
    1. scibot 19 May 2023
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2023.112522

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    sciencedirect.com/science/article/pii/S2211124723005338
  8. www.sciencedirect.com www.sciencedirect.com
    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
    1
    1. scibot 18 May 2023
      RRID:AB_2755041

      DOI: 10.1016/j.isci.2023.106758

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    sciencedirect.com/science/article/pii/S2589004223008350
  9. Mar 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
    1
    1. scibot 28 Mar 2023
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2023.02.014

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    sciencedirect.com/science/article/pii/S1074761323000882
  11. Feb 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation
    1
    1. scibot 16 Feb 2023
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2023.01.015

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    sciencedirect.com/science/article/pii/S1074761323000250
  13. Jan 2023
  14. www.science.org www.science.org
    Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis
    1
    1. scibot 26 Jan 2023
      AB_2755041

      DOI: 10.1126/scisignal.abh1083

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    science.org/doi/10.1126/scisignal.abh1083
  15. Dec 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
    1
    1. scibot 17 Dec 2022
      AB_2755041

      DOI: 10.7554/eLife.78609

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    ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
  17. Nov 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    1
    1. scibot 24 Nov 2022
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2022.111688

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    sciencedirect.com/science/article/pii/S2211124722015625
  19. Oct 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
    1
    1. scibot 26 Oct 2022
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2022.111532

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    sciencedirect.com/science/article/pii/S2211124722013882
  21. www.science.org www.science.org
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 25 Oct 2022
      RRID:AB_2755041

      DOI: 10.1126/sciadv.abn6545

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    science.org/doi/10.1126/sciadv.abn6545
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
    1
    1. scibot 07 Oct 2022
      RRID:AB_2755041

      DOI: 10.1126/sciadv.abn6545

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    ncbi.nlm.nih.gov/pmc/articles/PMC9491709/
  23. www.sciencedirect.com www.sciencedirect.com
    Non-canonical inflammasome activation analysis in a mouse model of Citrobacter rodentium infection
    1
    1. scibot 06 Oct 2022
      RRID:AB_2755041

      DOI: 10.1016/j.xpro.2022.101741

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    sciencedirect.com/science/article/pii/S2666166722006219
  24. Jun 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
    1
    1. scibot 02 Jun 2022
      RRID:AB_2755041

      DOI: 10.1016/j.neuron.2022.05.009

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    sciencedirect.com/science/article/pii/S0896627322004500
  26. Mar 2022
  27. www.hindawi.com www.hindawi.com
    Temporal Characterization of Microglia-Associated Pro- and Anti-Inflammatory Genes in a Neonatal Inflammation-Sensitized Hypoxic-Ischemic Brain Injury Model
    1
    1. scibot 26 Mar 2022
      RRID:AB_2755041

      DOI: 10.1155/2022/2479626

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    hindawi.com/journals/omcl/2022/2479626/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal Characterization of Microglia-Associated Pro- and Anti-Inflammatory Genes in a Neonatal Inflammation-Sensitized Hypoxic-Ischemic Brain Injury Model
    1
    1. scibot 11 Mar 2022
      RRID:AB_2755041

      DOI: 10.1155/2022/2479626

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    ncbi.nlm.nih.gov/pmc/articles/PMC8906938/
  29. Feb 2022
  30. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
    2
    1. scibot 11 Feb 2022
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2022.01.003

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    2. scibot 09 Feb 2022
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2022.01.003

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    pubmed.ncbi.nlm.nih.gov/35139355/
  31. Nov 2021
  32. www.sciencedirect.com www.sciencedirect.com
    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
    1
    1. scibot 09 Nov 2021
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2021.10.004

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    sciencedirect.com/science/article/pii/S1074761321004106
  33. Aug 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shigella OspC3 suppresses murine cytosolic LPS sensing
    1
    1. scibot 19 Aug 2021
      RRID:AB_2755041

      DOI: 10.1016/j.isci.2021.102910

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    ncbi.nlm.nih.gov/pmc/articles/PMC8361271/
  35. Jun 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
    1
    1. scibot 12 Jun 2021
      AG-20B-0042-C100

      DOI: 10.1016/j.immuni.2021.05.004

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    sciencedirect.com/science/article/pii/S1074761321002107
  37. Mar 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
    1
    1. scibot 13 Mar 2021
      AB_2755041

      DOI: 10.3389/fimmu.2021.620238

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    ncbi.nlm.nih.gov/pmc/articles/PMC7947244/
  39. Feb 2021
  40. www.nature.com www.nature.com
    A comprehensive guide to studying inflammasome activation and cell death
    1
    1. scibot 26 Feb 2021
      RRID:AB_2755041

      DOI: 10.1038/s41596-020-0374-9

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    nature.com/articles/s41596-020-0374-9
  41. Sep 2020
  42. www.sciencedirect.com www.sciencedirect.com
    The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation
    1
    1. scibot 10 Sep 2020
      RRID:AB_2755041

      DOI: 10.1016/j.cmet.2020.07.016

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      RRIDCUR:Validated RRID:AB_2755041
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    sciencedirect.com/science/article/pii/S1550413120304113
  43. www.sciencedirect.com www.sciencedirect.com
    Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    1
    1. scibot 10 Sep 2020
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2020.107967

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    sciencedirect.com/science/article/pii/S2211124720309487
  44. www.sciencedirect.com www.sciencedirect.com
    A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
    1
    1. scibot 08 Sep 2020
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2020.03.030

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720303442
  45. www.sciencedirect.com www.sciencedirect.com
    An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
    1
    1. scibot 05 Sep 2020
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2020.107959

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    sciencedirect.com/science/article/pii/S2211124720309402
  46. Jan 2020
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2755041

      DOI: 10.1016/j.immuni.2019.04.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6791531/