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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s44318-026-00783-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13270093/
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CF10 Displays Improved Synergy with Oxaliplatin in TP53-Null and Wild-Type CRC Cells from Increased Top1cc and Replication Stress

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1. scibot 17 Mar 2026
  
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  DOI: 10.3390/cancers18050882
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12984549/
Jan 2026
54.241.53.176 54.241.53.176

2026.01.09.698661v1.full-html.html

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1. scibot 13 Jan 2026
  
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  RRID:AB_2756354
  
  DOI: 10.64898/2026.01.09.698661
  
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54.241.53.176/229f150d292937106a4e15fcfbf1923f59503af0/2026.01.09.698661v1.full-html.html
May 2025
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Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.012
  
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sciencedirect.com/science/article/pii/S0092867425004143
Sep 2024
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TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.020
  
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sciencedirect.com/science/article/pii/S0092867424009115
Jul 2024
52.53.155.43 52.53.155.43

paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html

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1. scibot 23 Jul 2024
  
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  DOI: 10.1038/s44318-024-00169-3
  
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52.53.155.43/697f670316e6408b23a0d9d6a185a0597054fbec/paul-chowdhuri-das-2024-tdp1-phosphorylation-by-cdk1-in-mitosis-promotes-mus81-dependent-repair-of-trapped-top1-dna-html.html
www.embopress.org www.embopress.org

TDP1 phosphorylation by CDK1 in mitosis promotes MUS81-dependent repair of trapped Top1-DNA covalent complexes

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1. scibot 23 Jul 2024
  
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  DOI: 10.1038/s44318-024-00169-3
  
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embopress.org/doi/10.1038/s44318-024-00169-3
May 2024
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TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114214
  
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sciencedirect.com/science/article/pii/S2211124724005424
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10875566/
Dec 2023
dx.doi.org dx.doi.org

Isolation and detection of DNA–protein crosslinks in mammalian cells

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1. scibot 17 Dec 2023
  
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  DOI: 10.1093/nar/gkad1178
  
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dx.doi.org/10.1093/nar/gkad1178
Apr 2023
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Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair

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1. scibot 14 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.03.021
  
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sciencedirect.com/science/article/pii/S1097276523002113
Dec 2021
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

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1. scibot 09 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110080
  
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sciencedirect.com/science/article/pii/S2211124721015710
Oct 2021
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Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

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1. scibot 16 Oct 2021
  
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  DOI: 10.1016/j.neuron.2021.09.040
  
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sciencedirect.com/science/article/pii/S0896627321007133
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 28 Jul 2021
  
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  RRID:AB_2756354
  
  DOI: 10.1016/j.celrep.2018.11.099
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6364303/
Apr 2021
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Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2020.11.011
  
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sciencedirect.com/science/article/pii/S2451945620304748
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2756354
  
  DOI: 10.1016/j.celrep.2018.11.099
  
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  RRID:AB_2756354 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718318904