94 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
    1
    1. scibot 07 Nov 2024
      RRID:AB_2756376

      DOI: 10.3389/fonc.2024.1441935

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    pmc.ncbi.nlm.nih.gov/articles/PMC11513249/
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
    1
    1. scibot 10 Sep 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cmet.2024.08.005

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    sciencedirect.com/science/article/pii/S1550413124003322
  5. Jul 2024
  6. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
    1
    1. scibot 25 Jul 2024
      RRID:AB_2756376

      DOI: 10.1126/science.adh4567

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    science.org/doi/10.1126/science.adh4567
  7. www.sciencedirect.com www.sciencedirect.com
    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
    1
    1. scibot 19 Jul 2024
      AB_2756376

      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
  8. www.cell.com www.cell.com
    Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer
    1
    1. scibot 18 Jul 2024
      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2024.06.001

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    cell.com/cancer-cell/fulltext/S1535-6108(24)00226-5
  9. www.sciencedirect.com www.sciencedirect.com
    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.012

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    sciencedirect.com/science/article/pii/S0092867424006524
  10. www.cell.com www.cell.com
    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
    1
    1. scibot 12 Jul 2024
      RRID:AB_2756376

      DOI: 10.1016/j.xcrm.2024.101648

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Landscape of tumoral ecosystem for enhanced anti-PD-1 immunotherapy by gut Akkermansia muciniphila
    1
    1. scibot 04 Jun 2024
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2024.114306

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    sciencedirect.com/science/article/pii/S221112472400634X
  13. May 2024
  14. www.sciencedirect.com www.sciencedirect.com
    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
    1
    1. scibot 08 May 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cmet.2024.04.015

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    sciencedirect.com/science/article/pii/S1550413124001359
  15. Apr 2024
  16. www.sciencedirect.com www.sciencedirect.com
    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
    1
    1. scibot 16 Apr 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cell.2024.03.019

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    sciencedirect.com/science/article/pii/S0092867424003106
  17. www.sciencedirect.com www.sciencedirect.com
    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2024.114088

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    sciencedirect.com/science/article/pii/S2211124724004169
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
    1
    1. scibot 03 Apr 2024
      RRID:AB_2756376

      DOI: 10.1158/1078-0432.CCR-23-1003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  19. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
      RRID:AB_2756376

      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  20. Mar 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
    1
    1. scibot 22 Mar 2024
      RRID:AB_2756376

      DOI: 10.1016/j.isci.2024.109366

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
  22. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
    1
    1. scibot 12 Mar 2024
      RRID:AB_2756376

      DOI: 10.1016/j.omton.2024.200766

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    52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
  23. Feb 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
    1
    1. scibot 15 Feb 2024
      RRID:AB_275637

      DOI: 10.1158/2767-9764.CRC-23-0399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
  25. Jan 2024
  26. www.nature.com www.nature.com
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
    1
    1. scibot 25 Jan 2024
      RRID:AB_2756376

      DOI: 10.1038/s41388-024-02947-z

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    nature.com/articles/s41388-024-02947-z
  27. www.sciencedirect.com www.sciencedirect.com
    Multi-omics of the gut microbial ecosystem in patients with microsatellite-instability-high gastrointestinal cancer resistant to immunotherapy
    1
    1. scibot 09 Jan 2024
      RRID:AB_2756376

      DOI: 10.1016/j.xcrm.2023.101355

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    sciencedirect.com/science/article/pii/S2666379123005724
  28. www.sciencedirect.com www.sciencedirect.com
    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
    2
    1. scibot 04 Jan 2024
      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.07.025

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      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.07.025

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    sciencedirect.com/science/article/pii/S1534580723003945
  29. Dec 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
    1
    1. scibot 20 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/0008-5472.CAN-23-1065

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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
    1
    1. scibot 15 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
  32. www.sciencedirect.com www.sciencedirect.com
    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
    1
    1. scibot 02 Dec 2023
      RRID:AB_2756376

      DOI: 10.1016/j.immuni.2023.11.002

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    sciencedirect.com/science/article/pii/S1074761323004831
  33. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
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      DOI: 10.1158/2159-8290.cd-23-0306

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    52.53.155.43/2d1591f4bcff82c10886f9ef5d1f22c1addeb365/cd-23-0306-html.html
  34. 52.53.155.43 52.53.155.43
    can-23-1065-html.html
    2
    1. scibot 01 Dec 2023
      RRID:AB_2756376

      DOI: 10.1158/0008-5472.can-23-1065

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      RRID:AB_2756376

      DOI: 10.1158/0008-5472.can-23-1065

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    52.53.155.43/9a4ebc518d925889ddaa33b397b4737aebb3357f/can-23-1065-html.html
  35. Nov 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
    1
    1. scibot 30 Nov 2023
      RRID:AB_2756376

      DOI: 10.1158/2767-9764.CRC-23-0265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  37. www.sciencedirect.com www.sciencedirect.com
    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.113362

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    sciencedirect.com/science/article/pii/S2211124723013748
  38. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  39. www.sciencedirect.com www.sciencedirect.com
    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
    1
    1. scibot 17 Nov 2023
      RRID:AB_2756376

      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
  40. Oct 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 27 Oct 2023
      RRID:AB_2756376

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  42. Aug 2023
  43. www.sciencedirect.com www.sciencedirect.com
    A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101154

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    sciencedirect.com/science/article/pii/S2666379123003075
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
    1
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      DOI: 10.1038/s43856-023-00336-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
    1
    1. scibot 10 Aug 2023
      RRID:AB_2756376

      DOI: 10.1016/j.isci.2023.107408

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    ncbi.nlm.nih.gov/pmc/articles/PMC10405072/
  46. www.sciencedirect.com www.sciencedirect.com
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
    1
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      RRID:AB_2756376

      DOI: 10.1016/j.ccell.2021.02.007

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    sciencedirect.com/science/article/pii/S1535610821001094
  47. Jul 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
    1
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      RRID:AB_2756376

      DOI: 10.1101/2023.06.27.546707

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    ncbi.nlm.nih.gov/pmc/articles/PMC10327161/
  49. Jun 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
    1
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      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.112704

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    sciencedirect.com/science/article/pii/S2211124723007155
  51. www.sciencedirect.com www.sciencedirect.com
    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
    1
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      RRID:AB_2756376

      DOI: 10.1016/j.celrep.2023.112693

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    sciencedirect.com/science/article/pii/S2211124723007040
  52. www.sciencedirect.com www.sciencedirect.com
    Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
    1
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      RRID:AB_2756376

      DOI: 10.1016/j.isci.2023.106916

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    sciencedirect.com/science/article/pii/S2589004223009938
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating an Adaptive Immune Response with a Telomerase-mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
    1
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      DOI: 10.1158/1535-7163.MCT-23-0039

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  54. 52.53.155.43 52.53.155.43
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  55. May 2023
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    Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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  63. Apr 2023
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    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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  67. Mar 2023
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    Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity
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  69. Jan 2023
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    The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer
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    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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  72. Dec 2022
  73. 52.53.155.43 52.53.155.43
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  74. Nov 2022
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    Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy
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  76. Sep 2022
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  79. Aug 2022
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  82. Jul 2022
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  84. Jun 2022
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  87. May 2022
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  90. Apr 2022
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  92. Mar 2022
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  95. Feb 2022
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    ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression
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  97. Dec 2021
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  99. Sep 2021
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  102. Aug 2021
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  104. Jun 2021
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  106. May 2021
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    Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [64Cu]Cu-NOTA-anti-CD8-Positron Emission Tomography
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  110. Apr 2021
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    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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  114. Mar 2021
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    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
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    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
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  117. Feb 2021
  118. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Peptides Derived From Insulin Granule Proteins are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.
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  119. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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  120. Jan 2021
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    Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing
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  122. Sep 2020
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    Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer
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    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
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  125. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras
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  127. Jan 2020
  128. www.sciencedirect.com www.sciencedirect.com
    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
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    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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