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Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity

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1. scibot 18 Apr 2026
  
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Targeting leucine-rich repeat kinase 2 overcomes resistance to oncolytic herpes simplex virus-based therapies in glioblastoma

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Mar 2026
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Understanding Glioblastoma Dynamics Using 3D Organoids and Engineered Extracellular Matrix

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54.241.53.176/e72524355eb321529f4dd9a65278a0820d03292a/1-s2.0-S2589004226007479-main-html.html
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L-Lactate reprograms tumor-associated macrophages to drive pancreatic cancer progression via BCL3 lactylation

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NN-01-195, a novel conjugate of HSP90 and AURKA inhibitors, effectively targets solid tumors

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Nociceptive neurons protect cancer cells against oxidative stress

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CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression

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pH-responsive CaCO3 nanoplatform amplifies SDT via calcium overload-ROS loop for deep tumor therapy

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USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis

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1. scibot 03 Mar 2026
  
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sciencedirect.com/science/article/pii/S2589004226003020
Feb 2026
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Construction of a clickable probe-based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

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1. scibot 26 Feb 2026
  
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  DOI: 10.1002/imt2.70107
  
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A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma

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1-s2.0-S2589004226002919-main-html.html

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1. scibot 12 Feb 2026
  
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Biomimetic hydrogel for the construction of patient-derived bladder cancer organoids with aggressive growth

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1. scibot 12 Feb 2026
  
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HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling

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1. scibot 10 Feb 2026
  
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  DOI: 10.1007/s11010-026-05491-4
  
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link.springer.com/article/10.1007/s11010-026-05491-4
Jan 2026
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NUSAP1 Recruits DAXX to Suppress HIF‐Driven Triple‐Negative Breast Cancer Progression

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METTL3/CD98-mediated glutamate efflux in CAFs drives CD8+ T cell exhaustion and impedes neoadjuvant immunochemotherapy

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The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

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Dec 2025
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NEXN targeting MYOCD by facilitating EMT-related β-catenin nuclear translocation modulates the metastasis of hepatocellular carcinoma

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Protocol for the generation of three-dimensional micropatterned neuroepithelial tissues using hPSCs, bioprinting, and matrix scaffolds

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Nov 2025
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Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy

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1-s2.0-S2589004225023971-main-html.html

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1-s2.0-S2589004225023156-main-html.html

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BPS Publications

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  DOI: 10.1111/bph.70220
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70220
Oct 2025
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PreTA-mediated metabolism of 5-fluorouracil by intratumoral Citrobacter freundii drives chemoresistance in pancreatic cancer

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STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency

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  DOI: 10.1016/j.chembiol.2025.10.001
  
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Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro

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  DOI: 10.1177/15347354251375951
  
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Zuojin Wan Suppresses the Progression of Colorectal Cancer by Inhibiting M2 Tumor-Associated Macrophages Through JAK2/STAT3 Signaling Pathway and In Vivo and In Vitro

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pmc.ncbi.nlm.nih.gov/articles/PMC12480819/
Sep 2025
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High-throughput bioprinting to produce micropatterened neuroepithelial tissues and model TSC2-deficient brain malformations

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A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

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Antibacterial hyaluronic acid hydrogel with sustained release of larazotide as effective colitis treatment

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  DOI: 10.1016/j.jconrel.2025.114205
  
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sciencedirect.com/science/article/pii/S016836592500817X
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RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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BDH2 promotes GLIPR1 promoter methylation and thus increases 5-FU sensitivity in colorectal cancer

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Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma

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GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer

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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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PRMT5-mediated methylation of METTL3 promotes cisplatin resistance in ovarian cancer by facilitating DNA repair mechanisms

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FMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer

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DSCC1 restrains 53BP1/RIF1 signaling at DNA double-strand breaks to promote homologous recombination repair

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Vagal pathway activation links chronic stress to decline in intestinal stem cell function

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7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death

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USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5

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Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling

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Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

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N6-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism

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Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy

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The in vivo effects of knockdown of long non-coding RNA XIST on fibroid growth and gene expression

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Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation

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Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer

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A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma

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LncRNA CARMN m6A demethylation by ALKBH5 inhibits mutant p53‐driven tumour progression through miR‐5683/FGF2

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Cancer-associated endocrine cells participate in pancreatic carcinogenesis

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Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma

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Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models

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Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers

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Neuronal activity promotes glioma progression by inducing proneural-to-mesenchymal transition in glioma stem cells

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A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8

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372-html.html

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N6-methyladenosine modification of B7-H3 mRNA promotes the development and progression of colorectal cancer

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CREB3L4 promotes hepatocellular carcinoma progression and decreases sorafenib chemosensitivity by promoting RHEB-mTORC1 signaling pathway

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Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis

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Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

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FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

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Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression

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Patient-derived organoids as personalized avatars and a potential immunotherapy model in cervical cancer

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Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis

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WIPF1 promotes gastric cancer progression by regulating PI3K/Akt signaling in a myocardin-dependent manner

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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis

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IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

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SSRN-id4493933-html.html

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Live-cell Imaging-based Dynamic vascular formation Assay for Antivascular Drug Evaluation and Screening

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IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma

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METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2

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N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis

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Stress Granules determine the Development of Obesity-associated Pancreatic Cancer

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Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma

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Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer

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Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes

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Allicin ameliorates IMQ-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A

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Ki67 testing in the clinical management of patients with non‑metastatic colorectal cancer: Detecting the optimal cut‑off value based on the Restricted Cubic Spline model

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Necroptosis plays a crucial role in the exacerbation of... : Neural Regeneration Research

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can-21-3822-html.html

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Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE

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Jun 2022
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mct-21-0848-html.html

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can-21-3868-html.html

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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

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PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway

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Calcium-activated chloride channel is involved in the onset of diarrhea triggered by EGFR tyrosine kinase inhibitor treatment in rats

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Untitled document

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