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ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance

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sciencedirect.com/science/article/pii/S2211124726010879
Aug 2026
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A maternal Polycomb imprint is maintained in early Drosophila development through lower-order methylation states

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pmc.ncbi.nlm.nih.gov/articles/PMC13494837/
Jul 2026
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YBX1 Confers immunosuppressive bone metastatic traits in non-small cell lung cancer

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1. scibot 30 Jul 2026
  
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  DOI: 10.1038/s41467-026-73931-2
  
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2026.07.11.737985.full-html.html

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A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death

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  DOI: 10.1016/j.cell.2026.06.037
  
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sciencedirect.com/science/article/pii/S0092867426007579
Jun 2026
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Pharmacologic reversion of Merkel cell carcinoma via CBP/p300 inhibition

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pmc.ncbi.nlm.nih.gov/articles/PMC12772197/
May 2026
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A reabsorption mechanism in Drosophila renal tubules maintains amino acid homeostasis

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biorxiv.org/content/10.64898/2026.05.07.723391v1
Jan 2026
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Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry

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1. scibot 16 Jan 2026
  
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  DOI: 10.1016/j.xpro.2025.104326
  
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sciencedirect.com/science/article/pii/S2666166725007324
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Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers

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1. scibot 06 Jan 2026
  
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  DOI: 10.1111/jnc.70341
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70341
Dec 2025
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NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA

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pmc.ncbi.nlm.nih.gov/articles/PMC12709618/
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Recruitment of FBXO22 for targeted degradation of NSD2

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1. scibot 02 Dec 2025
  
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  DOI: 10.1038/s41589-024-01660-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11581931/
Oct 2025
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SMARCA1 regulates PARP1-dependent ABC transporters expression and mediates doxorubicin resistance in triple-negative breast cancer

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1. scibot 29 Oct 2025
  
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  DOI: 10.1016/j.biopha.2025.118698
  
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sciencedirect.com/science/article/pii/S0753332225008923
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Targeted citrullination enables p53 binding to non-canonical sites

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.09.004
  
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sciencedirect.com/science/article/pii/S1097276525007452
Sep 2025
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Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate

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1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.cmet.2025.08.010
  
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sciencedirect.com/science/article/pii/S1550413125003833
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Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism

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1. scibot 10 Sep 2025
  
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  DOI: 10.7554/eLife.104138
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12416886/
May 2025
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Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cmet.2025.04.015
  
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sciencedirect.com/science/article/pii/S1550413125002530
Jan 2025
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Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.024
  
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sciencedirect.com/science/article/pii/S1534580724007639
Dec 2024
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A nonsecretory antimicrobial peptide mediates inflammatory organ damage in Drosophila renal tubules

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1. scibot 24 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115082
  
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sciencedirect.com/science/article/pii/S2211124724014335
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The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma

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1. scibot 12 Dec 2024
  
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  DOI: 10.1093/nar/gkae1121
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1121/7917111
Jul 2024
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ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

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1. scibot 31 Jul 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
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1-s2.0-S2589004224017851-main-html.html

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52.53.155.43/28f1f0cd51770599356cfb72d036c0e468b38b34/1-s2.0-S2589004224017851-main-html.html
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BPS Publications

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1. scibot 18 Jul 2024
  
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  DOI: 10.1111/bph.16439
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16439
Jun 2024
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Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

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  DOI: 10.1016/j.isci.2024.109991
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11154205/
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Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1

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sciencedirect.com/science/article/pii/S2589004224010502
Feb 2024
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EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis

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1. scibot 09 Feb 2024
  
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sciencedirect.com/science/article/pii/S2211124724000421
Nov 2023
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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.biopha.2023.115798
  
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sciencedirect.com/science/article/pii/S0753332223015962
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Recruitment of FBXO22 for Targeted Degradation of NSD2

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1. scibot 10 Nov 2023
  
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  DOI: 10.1101/2023.11.01.564830
  
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biorxiv.org/content/10.1101/2023.11.01.564830v1
Aug 2023
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ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112937
  
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  DOI: 10.1016/j.celrep.2023.112937
  
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52.53.155.43/5c44b570825d260ed49e3beddaa9d47779a57883/PIIS2211124723009488-html.html
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Nuclear transport surveillance of p53 by nuclear pores in glioblastoma

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  DOI: 10.1016/j.celrep.2023.112882
  
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  DOI: 10.1016/j.celrep.2023.112882
  
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52.53.155.43/64ae675a86b73874b1bb5c50aa8d9678e93e36d6/PIIS2211124723008938-html.html
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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

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1. scibot 01 Aug 2023
  
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  DOI: 10.1038/s41594-023-01044-1
  
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nature.com/articles/s41594-023-01044-1
Jun 2023
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Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

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  DOI: 10.1016/j.isci.2023.107028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
May 2023
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Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.isci.2023.106774
  
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sciencedirect.com/science/article/pii/S2589004223008519
Apr 2023
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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation

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BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

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Oct 2022
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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas

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Mar 2022
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Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma

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Jan 2022
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Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation

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Sep 2021
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ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance

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Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation

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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

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May 2021
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Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas

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Mar 2021
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Targeting the mitochondrial permeability transition pore for neuroprotection in a piglet model of neonatal hypoxic‐ischemic encephalopathy

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BPS Publications

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Jan 2020
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EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

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Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

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Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

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  DOI: 10.1016/j.celrep.2019.08.105
  
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Untitled document

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