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    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
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      DOI: 10.1016/j.cell.2024.10.012

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    sciencedirect.com/science/article/pii/S0092867424011887
  3. Nov 2024
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    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
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  5. Sep 2024
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    RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages
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    Aldehydes alter TGF-β signaling and induce obesity and cancer
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    sciencedirect.com/science/article/pii/S2211124724010271
  8. Aug 2024
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data
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    biorxiv.org/content/10.1101/2024.08.01.606198v1
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    SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation
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    link.springer.com/article/10.1007/s00395-021-00865-9/tables/2
  12. Jul 2024
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    Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation
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    sciencedirect.com/science/article/pii/S0141813024049250
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    The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation
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    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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  16. Jun 2024
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    Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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  19. May 2024
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    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
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    sciencedirect.com/science/article/pii/S1535610824001636
  21. Apr 2024
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    4R-cembranoid suppresses glial cells inflammatory phenotypes and prevents hippocampal neuronal loss in LPS-treated mice
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    Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease
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    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
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    aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
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    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
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    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
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    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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  28. Mar 2024
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    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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    Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
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    Interrogating endothelial barrier regulation by temporally resolved kinase network generation
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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  34. Feb 2024
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    Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
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    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  41. Jan 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice
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  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    The Crucial Role of Single-Stranded DNA Binding in Enhancing Sensitivity to DNA-Damaging Agents for Schlafen 11 and Schlafen 13
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    Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus
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      DOI: 10.1210/clinem/dgad699

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  46. Nov 2023
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    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
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  48. Oct 2023
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    A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
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  50. Sep 2023
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
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    Taok1 haploinsufficiency leads to autistic-like behaviors in mice via the dorsal raphe nucleus
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  53. Aug 2023
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    Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes
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  55. Jul 2023
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    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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  58. Jun 2023
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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  60. May 2023
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    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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  62. Mar 2023
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    Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing
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  65. Jan 2023
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    mTORC2 loss in oligodendrocyte progenitor cells results in regional hypomyelination in the central nervous system
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  67. Dec 2022
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    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  70. Nov 2022
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    Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2
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    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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  74. Oct 2022
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    Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection
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  76. Sep 2022
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    Exploring ABOBEC3A and APOBEC3B Substrate Specificity and Their Role in HPV Positive Head and Neck Cancer
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  78. Jul 2022
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    Role of Constitutive STAR in Mitochondrial Structure and Function in MA-10 Leydig Cells
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  80. Jun 2022
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    Circulating Protein Disulfide Isomerase is associated with increased risk of Thrombosis in JAK2-mutated Myeloproliferative Neoplasms
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  82. May 2022
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    STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
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    Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine
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  86. Mar 2022
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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    Loss of Slc38a4 imprinting is a major cause of mouse placenta hyperplasia in somatic cell nuclear transferred embryos at late gestation
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    The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
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  91. Dec 2021
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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  93. Nov 2021
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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  95. Oct 2021
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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  97. Sep 2021
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    Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells
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  99. Aug 2021
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    Loss of CREB coactivator CRTC1 in SF1 cells leads to hyperphagia and obesity by high-fat diet but not normal chow diet
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    An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
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    RNA-binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH
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  103. Jul 2021
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    Developmental SMAD6 Loss Leads to Blood Vessel Hemorrhage and Disrupted Endothelial Cell Junctions
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      Mouse monoclonal anti-GAPDH

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  105. May 2021
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    MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells
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    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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  108. Apr 2021
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    Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
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    BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
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  111. Mar 2021
  112. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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  113. Jan 2021
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    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
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    The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer
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  116. Sep 2020
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    Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress
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    ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin
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  119. elifesciences.org elifesciences.org
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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
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  121. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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  122. mct.aacrjournals.org mct.aacrjournals.org
    Novel Miniaturized Drug Conjugate Leverages HSP90 Driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors
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  123. www.mdpi.com www.mdpi.com
    Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib
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    YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA
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  125. Jan 2020
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    A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation
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    Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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      DOI: 10.1016/j.celrep.2019.07.021

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  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes
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  130. elifesciences.org elifesciences.org
    Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity
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  131. wellcomeopenresearch.org wellcomeopenresearch.org
    Proteomic analysis of a filaggrin-deficient skin organoid model shows evidence of increased transcriptional-translational activity, keratinocyte-immune crosstalk and disordered axon guidance
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      DOI: 10.12688/wellcomeopenres.15405.1

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model
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      DOI: 10.12688/wellcomeopenres.15405.2

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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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