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  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    4R-cembranoid suppresses glial cells inflammatory phenotypes and prevents hippocampal neuronal loss in LPS-treated mice
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    1. scibot 25 Apr 2024
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      DOI: 10.1002/jnr.25336

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  3. Apr 2024
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    Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S221112472400456X
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    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
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      DOI: 10.1158/0008-5472.CAN-23-1459

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    aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
  6. www.biorxiv.org www.biorxiv.org
    The BLM-TOP3A-RMI1-RMI2 proximity map reveals that RAD54L2 suppresses sister chromatid exchanges
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    1. scibot 12 Apr 2024
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      DOI: 10.1101/2024.04.07.588476

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    biorxiv.org/content/10.1101/2024.04.07.588476v1
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    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
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    sciencedirect.com/science/article/pii/S1934590924000924
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    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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    1. scibot 20 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10946310/
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    Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
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    sciencedirect.com/science/article/pii/S2211124724002250
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    Interrogating endothelial barrier regulation by temporally resolved kinase network generation
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    1. scibot 13 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10927359/
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    sciencedirect.com/science/article/pii/S1097276524001291
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    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  15. Feb 2024
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    Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development
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    sciencedirect.com/science/article/pii/S2589004224004012
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    1. scibot 29 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000972
  18. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
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    sciencedirect.com/science/article/pii/S2211124724000895
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  21. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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      DOI: 10.1038/s41467-024-45067-8

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    nature.com/articles/s41467-024-45067-8
  22. Jan 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice
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    1. scibot 24 Jan 2024
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      DOI: 10.3389/fcvm.2023.1323760

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    ncbi.nlm.nih.gov/pmc/articles/PMC10800928/
  24. Dec 2023
  25. www.sciencedirect.com www.sciencedirect.com
    The Crucial Role of Single-Stranded DNA Binding in Enhancing Sensitivity to DNA-Damaging Agents for Schlafen 11 and Schlafen 13
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      DOI: 10.1016/j.isci.2023.108529

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    sciencedirect.com/science/article/pii/S2589004223026068
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    Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus
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      DOI: 10.1210/clinem/dgad699

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    dx.doi.org/10.1210/clinem/dgad699
  27. Nov 2023
  28. www.sciencedirect.com www.sciencedirect.com
    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
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    sciencedirect.com/science/article/pii/S2211124723012640
  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
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    sciencedirect.com/science/article/pii/S221112472301272X
  31. Sep 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
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    sciencedirect.com/science/article/pii/S1097276523006950
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    Taok1 haploinsufficiency leads to autistic-like behaviors in mice via the dorsal raphe nucleus
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    sciencedirect.com/science/article/pii/S2211124723010896
  34. Aug 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes
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      DOI: 10.1016/j.isci.2023.107618

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    sciencedirect.com/science/article/pii/S2589004223016954
  36. Jul 2023
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    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    sciencedirect.com/science/article/pii/S2211124723008185
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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      DOI: 10.1016/j.biopha.2023.115038

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    sciencedirect.com/science/article/pii/S0753332223008284
  39. Jun 2023
  40. www.nature.com www.nature.com
    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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  41. May 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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    sciencedirect.com/science/article/pii/S2211124723004588
  43. Mar 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing
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      DOI: 10.1016/j.neuron.2023.02.021

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    sciencedirect.com/science/article/pii/S0896627323001253
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    BPS Publications
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      DOI: 10.1111/bph.16047

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16047
  46. Jan 2023
  47. www.jneurosci.org www.jneurosci.org
    mTORC2 loss in oligodendrocyte progenitor cells results in regional hypomyelination in the central nervous system
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      DOI: 10.1523/JNEUROSCI.0010-22.2022

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    jneurosci.org/content/43/4/540
  48. Dec 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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      DOI: 10.7554/eLife.78609

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    ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
  50. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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      DOI: 10.1158/2159-8290.CD-21-1491

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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  51. Nov 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2
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    ncbi.nlm.nih.gov/pmc/articles/PMC9672403/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
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      DOI: 10.1016/j.isci.2022.105419

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    ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide)
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      DOI: 10.1016/j.isci.2022.105431

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    ncbi.nlm.nih.gov/pmc/articles/PMC9646960/
  55. Oct 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9474420/
  57. Sep 2022
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    Exploring ABOBEC3A and APOBEC3B Substrate Specificity and Their Role in HPV Positive Head and Neck Cancer
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  59. Jul 2022
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    Role of Constitutive STAR in Mitochondrial Structure and Function in MA-10 Leydig Cells
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  61. Jun 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating Protein Disulfide Isomerase is associated with increased risk of Thrombosis in JAK2-mutated Myeloproliferative Neoplasms
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  63. May 2022
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    STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
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    Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti-inflammatory lipid N-acylethanolamine
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  67. Mar 2022
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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  69. Feb 2022
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    Loss of Slc38a4 imprinting is a major cause of mouse placenta hyperplasia in somatic cell nuclear transferred embryos at late gestation
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    The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
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  72. Dec 2021
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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  74. Nov 2021
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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  76. Oct 2021
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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  78. Sep 2021
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    Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells
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  80. Aug 2021
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    Loss of CREB coactivator CRTC1 in SF1 cells leads to hyperphagia and obesity by high-fat diet but not normal chow diet
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    An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
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    RNA-binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH
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  84. Jul 2021
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    Developmental SMAD6 Loss Leads to Blood Vessel Hemorrhage and Disrupted Endothelial Cell Junctions
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      Mouse monoclonal anti-GAPDH

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  86. May 2021
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    MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells
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    HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
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  89. Apr 2021
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    Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
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    BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
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  92. Mar 2021
  93. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence
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  94. Jan 2021
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    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
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    The Reprimo-Like Gene Is an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer
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  97. Sep 2020
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    Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress
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    ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin
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    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
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    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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    Novel Miniaturized Drug Conjugate Leverages HSP90 Driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors
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    Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib
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      anti-GAPDH

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    YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA
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      monoclonal mouse anti-GAPDH

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  106. Jan 2020
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    A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation
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    Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes
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    Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity
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    Proteomic analysis of a filaggrin-deficient skin organoid model shows evidence of increased transcriptional-translational activity, keratinocyte-immune crosstalk and disordered axon guidance
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model
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      DOI: 10.12688/wellcomeopenres.15405.2

      Resource: (Cell Signaling Technology Cat# 97166, RRID:AB_2756824)

      Curator: @evieth

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      RRID:AB_2756824 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6790913/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 13 Jan 2020
      RRID:AB_2756824

      DOI: 10.7554/eLife.44161

      Resource: (Cell Signaling Technology Cat# 97166, RRID:AB_2756824)

      Curator: @evieth

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      RRID:AB_2756824 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6436895/
  115. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2756824

      DOI: 10.1016/j.molcel.2019.03.018

      Resource: (Cell Signaling Technology Cat# 97166, RRID:AB_2756824)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2756824

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      RRID:AB_2756824 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519302229