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Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

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Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

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sciencedirect.com/science/article/pii/S2211124725009222
Aug 2025
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A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro

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1. scibot 28 Aug 2025
  
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Lymphatic dysfunction correlates with inflammation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

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  DOI: 10.1242/dmm.052148
  
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Jul 2025
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Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects

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sciencedirect.com/science/article/pii/S0896627325004751
Jun 2025
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Generation of a LEUTX-2A-mCherry knock-in H1 human embryonic stem cell line using CRISPR/Cas9 system

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May 2025
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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease

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sciencedirect.com/science/article/pii/S1074761325001384
Apr 2025
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Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression

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  DOI: 10.1016/j.celrep.2025.115592
  
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sciencedirect.com/science/article/pii/S2211124725003638
Mar 2025
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Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

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  DOI: 10.1016/j.stem.2025.02.015
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9
Feb 2025
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FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma

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sciencedirect.com/science/article/pii/S1535610825000534
Jan 2025
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Postprandial parasympathetic signals promote lung type 2 immunity

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  DOI: 10.1016/j.neuron.2024.12.020
  
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PDF-html.html

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52.53.155.43/d05ab25f6245424059e477ea01a07a6495a79e4a/PDF-html.html
Aug 2024
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Non-canonical function of ADAM10 in presynaptic plasticity

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1. scibot 23 Aug 2024
  
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  DOI: 10.1007/s00018-024-05327-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11335265/
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LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration

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  DOI: 10.1038/s42255-024-01110-y
  
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nature.com/articles/s42255-024-01110-y
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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

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ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
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Maternal fluoxetine impairs synaptic transmission and plasticity in the medial prefrontal cortex and alters the structure and function of dorsal raphe nucleus neurons in offspring mice

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sciencedirect.com/science/article/pii/S0091305724001436
Jul 2024
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FEBS Press

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1. scibot 23 Jul 2024
  
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  DOI: 10.1002/1873-3468.14978
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14978
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The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

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cell.com/cell-metabolism/fulltext/S1550-4131(24)00231-6
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Generation of MBP-tdTomato reporter human induced pluripotent stem cell line for live myelin visualization

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Jun 2024
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Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1

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TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons

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Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

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52.53.155.43/be49547c4f9e1293474726024249294abe2db848/2024.02.09.579580v1.full-html.html
May 2024
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AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells

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2024.02.09.579580v1.full-html.html

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1. scibot 10 May 2024
  
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  DOI: 10.1038/nature05972
  
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52.53.155.43/32c668e9e171a0d93bacd7fd25061d69f59c1b8d/2024.02.09.579580v1.full-html.html
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Epstein–Barr Virus BALF0/1 Subverts the Caveolin and ERAD Pathways to Target B-cell Receptor Complexes for Degradation

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biorxiv.org/content/10.1101/2024.01.04.574276v1
Feb 2024
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PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication

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  DOI: 10.1016/j.isci.2024.109033
  
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Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation

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  DOI: 10.1101/2024.02.07.579368
  
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Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition

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Jan 2024
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Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

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  DOI: 10.1016/j.ccell.2023.12.018
  
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Dec 2023
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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  DOI: 10.1016/j.immuni.2023.11.018
  
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Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture

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  DOI: 10.1016/j.cell.2023.11.008
  
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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

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  DOI: 10.1016/j.celrep.2023.113529
  
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sciencedirect.com/science/article/pii/S2211124723015413
Nov 2023
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The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability

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  DOI: 10.1016/j.celrep.2023.113374
  
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sciencedirect.com/science/article/pii/S2211124723013864
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Spatial memory requires hypocretins to elevate medial entorhinal gamma oscillations

1
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  DOI: 10.1016/j.neuron.2023.10.012
  
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Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

1
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  DOI: 10.1101/2023.11.08.566308
  
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biorxiv.org/content/10.1101/2023.11.08.566308v1
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Highly-parallel production of designer organoids by mosaic patterning of progenitors

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  DOI: 10.1101/2023.10.25.564017
  
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biorxiv.org/content/10.1101/2023.10.25.564017v1
Sep 2023
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Anatomical identification of a corticocortical top-down recipient inhibitory circuitry by enhancer-restricted transsynaptic tracing

1
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  DOI: 10.3389/fncir.2023.1245097
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10502327/
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3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages

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  DOI: 10.1016/j.stem.2023.08.005
  
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Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8

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  DOI: 10.1016/j.xcrm.2023.101175
  
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Aug 2023
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Generation of four induced pluripotent stem cells lines from PBMC of the DFNA58 family members: Two hearing-impaired duplication carriers (USPi006-A e USPi007-A) and two normal-hearing noncarriers (USPi004-A and USPi005-A)

1
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Supplemental_Material.doc-html.html

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  DOI: 10.2337/db22-0745
  
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52.53.155.43/f40c8204621797818d872b387b2c0141763e87fb/Supplemental_Material.doc-html.html
Jul 2023
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Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons

1
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Cell Competition Shapes Metastatic Latency and Relapse

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  DOI: 10.1158/2159-8290.CD-22-0236
  
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Shedding light on human olfaction: Electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium

1
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Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-like Phenotype

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jneurosci.org/content/43/27/5092
May 2023
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Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex

1
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Apr 2023
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Inhibiting phosphatase and actin regulator 1 expression is neuroprotective in the context of traumatic brain injury

1
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  DOI: 10.4103/1673-5374.357904
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10075113/
Mar 2023
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A tri-specific killer engager against mesothelin targets NK cells towards lung cancer

1
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Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons

1
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  DOI: 10.3390/ph16030343
  
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mdpi.com/1424-8247/16/3/343
Jan 2023
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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

1
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  DOI: 10.1016/j.immuni.2022.11.013
  
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sciencedirect.com/science/article/pii/S1074761322006033
Dec 2022
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A reference human induced pluripotent stem cell line for large-scale collaborative studies

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Anatomical barriers against SARS-CoV-2 neuroinvasion at vulnerable interfaces visualized in deceased COVID-19 patients

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  DOI: 10.1016/j.neuron.2022.11.007
  
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Suspension culture in a rotating bioreactor for efficient generation of human intestinal organoids

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  DOI: 10.1016/j.crmeth.2022.100337
  
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Cell-type identity of the avian utricle

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  DOI: 10.1016/j.celrep.2022.111432
  
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The parabigeminal nucleus is a source of “retinogeniculate replacement terminals” in mice that lack retinofugal input

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Aug 2022
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Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury

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The presynaptic active zone protein Bassoon as a marker for synapses between Type III cells and afferent nerve fibers in taste buds

1
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academic.oup.com/chemse/article/doi/10.1093/chemse/bjac016/6619055
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Generation of two iPSC lines (UMi038-A & UMi039-A) from siblings bearing an Alzheimer’s disease-associated variant in SORL1

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Mar 2022
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BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states

1
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Jan 2022
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SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model

1
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A stress-reduced passaging technique improves the viability of human pluripotent cells

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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

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Sep 2021
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The Organization of Cholinergic Projections in the Visual Thalamus of the Mouse

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  DOI: 10.1002/cne.25235
  
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onlinelibrary.wiley.com/doi/10.1002/cne.25235
Jul 2021
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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

1
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  Donkey anti-goat Alexa Fluor 647
  
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May 2021
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Generation of a Friedreich’s Ataxia patient-derived iPSC line USFi001-A

1
1. scibot 20 May 2021
  
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  DOI: 10.1016/j.scr.2021.102399
  
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Generation of a heterozygous FLNC mutation-carrying human iPSC line, USFi002-A, for modeling dilated cardiomyopathy

1
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  DOI: 10.1016/j.scr.2021.102394
  
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The embryonic ontogeny of the gonadal somatic cells in mice and monkeys

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  DOI: 10.1016/j.celrep.2021.109075
  
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Apr 2021
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High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

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1. scibot 23 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.04.036
  
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sciencedirect.com/science/article/pii/S0092867420305018
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Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer

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1. scibot 17 Apr 2021
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.ccell.2020.05.019
  
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sciencedirect.com/science/article/pii/S1535610820302695
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Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

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1. scibot 17 Apr 2021
  
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  RRID:AB_2762840
  
  DOI: 10.1038/s41593-020-00794-1
  
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  Curator: @evieth
  
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nature.com/articles/s41593-020-00794-1
Sep 2020
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

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1. scibot 26 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.immuni.2020.03.001
  
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sciencedirect.com/science/article/pii/S1074761320300893
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Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from an arrhythmogenic cardiomyopathy patient carrying the c.2013delC PKP2 mutation

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1. scibot 23 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.scr.2020.101835
  
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  RRID:AB_2762840 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1873506120301367
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Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis

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1. scibot 17 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.celrep.2020.02.024
  
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sciencedirect.com/science/article/pii/S2211124720301856
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Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene

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1. scibot 16 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.scr.2020.101764
  
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sciencedirect.com/science/article/pii/S1873506120300684
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Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network

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1. scibot 09 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.molcel.2020.03.009
  
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sciencedirect.com/science/article/pii/S109727652030157X
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A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.cell.2020.06.011
  
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sciencedirect.com/science/article/pii/S009286742030742X
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Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration

1
1. scibot 03 Sep 2020
  
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  A32849
  
  DOI: 10.1016/j.stem.2019.12.014
  
  Resource: (Thermo Fisher Scientific Cat# A32849, RRID:AB_2762840)
  
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sciencedirect.com/science/article/pii/S1934590919305727
Jan 2020
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Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development

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1. scibot 13 Jan 2020
  
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  RRID:AB_2762840
  
  DOI: 10.1016/j.celrep.2019.09.048
  
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sciencedirect.com/science/article/pii/S2211124719312367
elifesciences.org elifesciences.org

In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

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1. scibot 13 Jan 2020
  
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  RRID:AB_2762840
  
  DOI: 10.7554/eLife.45916
  
  Resource: (Thermo Fisher Scientific Cat# A32849, RRID:AB_2762840)
  
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elifesciences.org/articles/45916

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