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54.241.53.176 54.241.53.176

2026.01.31.703051.full-html.html

1
1. scibot 12 Feb 2026
  
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  AB_2773729
  
  DOI: 10.64898/2026.01.31.703051
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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54.241.53.176/817d1ae27212347f382894a7416c0a21d3d8e9f2/2026.01.31.703051.full-html.html
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis

1
1. scibot 22 Jul 2025
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2025.116032
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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sciencedirect.com/science/article/pii/S2211124725008034
May 2025
www.nature.com www.nature.com

ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression

1
1. scibot 19 May 2025
  
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  RRID:AB_2773729
  
  DOI: 10.1038/s41556-025-01651-8
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
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nature.com/articles/s41556-025-01651-8
May 2024
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle

1
1. scibot 24 May 2024
  
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  RRID:AB_2773729
  
  DOI: 10.1113/JP285719
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
Feb 2024
52.53.155.43 52.53.155.43

Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice

2
1. scibot 22 Feb 2024
  
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  RRID:AB_2773729
  
  DOI: 10.1101/2023.09.01.555935
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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  RRID:AB_2773729
2. scibot 22 Feb 2024
  
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  RRID:AB_2773729
  
  DOI: 10.1101/2023.09.01.555935
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
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52.53.155.43/fd6bbeebd50ae2c0912f6e8604e8bc905b0c2518/2023.09.01.555935v1.full-html.html
www.sciencedirect.com www.sciencedirect.com

Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer

1
1. scibot 16 Feb 2024
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.molmet.2024.101900
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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sciencedirect.com/science/article/pii/S2212877824000310
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice

1
1. scibot 04 Nov 2023
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.isci.2023.108196
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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sciencedirect.com/science/article/pii/S2589004223022733
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Lactate activates the mitochondrial electron transport chain independently of its metabolism

1
1. scibot 28 Oct 2023
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.molcel.2023.09.034
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276523008006
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes

1
1. scibot 16 Jun 2023
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2023.112641
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
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sciencedirect.com/science/article/pii/S2211124723006526
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway

1
1. scibot 26 Oct 2022
  
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  RRID:AB_2773729
  
  DOI: 10.1126/sciadv.abq0117
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9524954/
www.science.org www.science.org

Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway

1
1. scibot 22 Oct 2022
  
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  RRID:AB_2773729
  
  DOI: 10.1126/sciadv.abq0117
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
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science.org/doi/10.1126/sciadv.abq0117
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells

1
1. scibot 13 Jul 2022
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2022.111069
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773729
  
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sciencedirect.com/science/article/pii/S2211124722008671
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy

1
1. scibot 26 Oct 2021
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.molcel.2021.10.001
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773729
  
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sciencedirect.com/science/article/pii/S1097276521008005
May 2021
www.sciencedirect.com www.sciencedirect.com

The f subunit of human ATP synthase is essential for normal mitochondrial morphology and permeability transition

1
1. scibot 12 May 2021
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2021.109111
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773729
  
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sciencedirect.com/science/article/pii/S2211124721004459
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure

1
1. scibot 30 Apr 2021
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.cmet.2020.12.003
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2773729
  
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sciencedirect.com/science/article/pii/S1550413120306586
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models

1
1. scibot 08 Sep 2020
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2020.01.060
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2773729
  
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  RRID:AB_2773729 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2773729

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sciencedirect.com/science/article/pii/S2211124720300851
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.cmet.2019.11.002
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2773729
  
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  RRID:AB_2773729 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2773729

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sciencedirect.com/science/article/pii/S1550413119306096
www.sciencedirect.com www.sciencedirect.com

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2019.05.066
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2773729
  
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  RRID:AB_2773729 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2773729

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sciencedirect.com/science/article/pii/S2211124719306953
www.sciencedirect.com www.sciencedirect.com

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2773729
  
  DOI: 10.1016/j.celrep.2019.07.098
  
  Resource: (Cell Signaling Technology Cat# 14462, RRID:AB_2773729)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2773729
  
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  RRID:AB_2773729 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2773729

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scibot

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sciencedirect.com/science/article/pii/S2211124719310149