45 Matching Annotations
  1. Jun 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726006376
  3. www.nature.com www.nature.com
    DNA replication stress and translational repression converge to drive CDK1- and caspase-dependent apoptosis in Ewing sarcoma
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    nature.com/articles/s41388-026-03845-2
  4. Feb 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting CAFs-Mediated Stromal Signaling in a Patient-Derived Organotypic Colorectal Tumor Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316546/
  6. Dec 2025
  7. www.nature.com www.nature.com
    CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen
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    nature.com/articles/s41523-025-00851-7
  8. Nov 2025
  9. www.tandfonline.com www.tandfonline.com
    Novel compounds with promising HuH-7 inhibitory activity as new cancer drug candidates: derivatives of N,N′-diphenylurea linked with 1,2,3-triazole
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    tandfonline.com/doi/abs/10.1080/14756366.2025.2585597
  10. Oct 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Chromatin remodeling activity of EP400 safeguards chromosomal stability by preventing CENP-A mislocalization
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    sciencedirect.com/science/article/pii/S2211124725011945
  12. Aug 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309138/
  14. Jun 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
  16. May 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147910/
  18. Apr 2025
  19. 52.53.155.43 52.53.155.43
    PDF-html.html
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  20. Jan 2025
  21. www.sciencedirect.com www.sciencedirect.com
    The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC
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    sciencedirect.com/science/article/pii/S2666379125000023
  22. www.jidonline.org www.jidonline.org
    5’-cap-dependent translation as a potent therapeutic target for lethal human squamous cell carcinoma
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    jidonline.org/article/S0022-202X(20)32066-2/fulltext
  23. Oct 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443213/
  25. Sep 2024
  26. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    UA influences the progression of breast cancer via the AhR/p27Kip1/cyclin E pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400938R
  27. Jul 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
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    ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
  29. www.biorxiv.org www.biorxiv.org
    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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    biorxiv.org/content/10.1101/2024.06.11.598518v2
  30. Jun 2024
  31. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  32. May 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  34. Mar 2024
  35. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    nature.com/articles/s41596-024-00970-8
  36. www.sciencedirect.com www.sciencedirect.com
    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    sciencedirect.com/science/article/pii/S0092867424002253
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905675/
  38. Feb 2024
  39. 52.53.155.43 52.53.155.43
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  40. www.sciencedirect.com www.sciencedirect.com
    Alternative mRNA splicing events and regulators in epidermal differentiation
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    sciencedirect.com/science/article/pii/S2211124724001426
  41. Nov 2023
  42. www.nature.com www.nature.com
    ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury
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    nature.com/articles/s41467-023-43439-0
  43. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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    pubmed.ncbi.nlm.nih.gov/37279095/
  44. Oct 2023
  45. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
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  46. Sep 2023
  47. link.springer.com link.springer.com
    Neuromedin B receptor as a potential therapeutic target for corticotroph adenomas
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    link.springer.com/article/10.1007/s11102-023-01350-3
  48. Aug 2023
  49. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
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  50. Jul 2023
  51. 52.53.155.43 52.53.155.43
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  52. Jan 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    sciencedirect.com/science/article/pii/S1097276522012175
  54. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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    sciencedirect.com/science/article/pii/S2211124723000426
  55. www.sciencedirect.com www.sciencedirect.com
    The human pre-replication complex is an open complex
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    sciencedirect.com/science/article/pii/S0092867422015215
  56. Dec 2022
  57. www.sciencedirect.com www.sciencedirect.com
    YAP regulates the liver size during the fasting-refeeding transition in mice
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    sciencedirect.com/science/article/pii/S2211383522005196
  58. Nov 2022
  59. www.sciencedirect.com www.sciencedirect.com
    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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    sciencedirect.com/science/article/pii/S2589004222014560
  60. Jul 2022
  61. www.embopress.org www.embopress.org
    LRH-1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance
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    embopress.org/doi/10.15252/embr.202154195
  62. Mar 2022
  63. www.sciencedirect.com www.sciencedirect.com
    Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain
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    sciencedirect.com/science/article/pii/S0361923022000582
  64. Dec 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
  66. Nov 2021
  67. www.sciencedirect.com www.sciencedirect.com
    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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    sciencedirect.com/science/article/pii/S2211124721014078
  68. Oct 2021
  69. www.sciencedirect.com www.sciencedirect.com
    A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
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    sciencedirect.com/science/article/pii/S0960982221012902
  70. Sep 2021
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
  72. Jun 2021
  73. www.sciencedirect.com www.sciencedirect.com
    miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3
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    sciencedirect.com/science/article/pii/S2211124721005763
  74. Oct 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo
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    sciencedirect.com/science/article/pii/S2212877820301599
  76. Jan 2020
  77. www.sciencedirect.com www.sciencedirect.com
    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
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    sciencedirect.com/science/article/pii/S1535610819305239