15 Matching Annotations
  1. Jun 2024
  2. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    1. scibot 29 Jun 2024
      RRID:AB_2783865

      DOI: 10.1016/j.isci.2024.109978

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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome
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    1. scibot 02 Feb 2024
      RRID:AB_2783865

      DOI: 10.1186/s13578-024-01198-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10829266/
  5. Jun 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    1
    1. scibot 17 Jun 2023
      RRID:AB_2783865

      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  7. May 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Replication stress impairs chromosome segregation and preimplantation development in human embryos
    1
    1. scibot 05 May 2023
      RRID:AB_2783865

      DOI: 10.1016/j.cell.2022.06.028

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    sciencedirect.com/science/article/pii/S0092867422007802
  9. www.nature.com www.nature.com
    Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
    1
    1. scibot 05 May 2023
      AB_2783865

      DOI: 10.1038/s41419-022-05073-4

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    nature.com/articles/s41419-022-05073-4
  10. Jun 2022
  11. www.sciencedirect.com www.sciencedirect.com
    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
    1
    1. scibot 30 Jun 2022
      RRID:AB_2783865

      DOI: 10.1016/j.devcel.2022.06.003

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    sciencedirect.com/science/article/pii/S1534580722004129
  12. www.sciencedirect.com www.sciencedirect.com
    A function for Ataxia telangiectasia and Rad3-related (ATR) kinase in cytokinetic abscission
    1
    1. scibot 17 Jun 2022
      RRID:AB_2783865

      DOI: 10.1016/j.isci.2022.104536

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    sciencedirect.com/science/article/pii/S2589004222008070
  13. Apr 2022
  14. aacrjournals.org aacrjournals.org
    DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-based Antibody-Drug Conjugate Targeting B7-H3 Exerts Potent Antitumor Activities in Preclinical Models
    1
    1. scibot 05 Apr 2022
      RRID:AB_2783865

      DOI: 10.1158/1535-7163.MCT-21-0554

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    aacrjournals.org/mct/article/21/4/635/689570/DS-7300a-a-DNA-Topoisomerase-I-Inhibitor-DXd-Based
  15. Feb 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis
    1
    1. scibot 12 Feb 2022
      RRID:AB_2783865

      DOI: 10.7554/eLife.68677

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    ncbi.nlm.nih.gov/pmc/articles/PMC8824475/
  17. Dec 2021
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
    1
    1. scibot 17 Dec 2021
      RRID:AB_2783865

      DOI: 10.7554/eLife.70691

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    ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
  19. Feb 2021
  20. www.nature.com www.nature.com
    Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51
    1
    1. scibot 09 Feb 2021
      RRID:AB_2783865

      DOI: 10.1038/s41418-020-00733-4

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      Curator: @evieth

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    nature.com/articles/s41418-020-00733-4
  21. Jan 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers
    1
    1. scibot 28 Jan 2021
      RRID:AB_2783865

      DOI: 10.3390/md19010041

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7831112/
  23. Sep 2020
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATR expands embryonic stem cell fate potential in response to replication stress
    1
    1. scibot 14 Sep 2020
      RRID:AB_2783865

      DOI: 10.7554/eLife.54756

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    ncbi.nlm.nih.gov/pmc/articles/PMC7067586/
  25. Jan 2020
  26. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_2783865

      DOI: 10.1016/j.cels.2019.11.001

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      Curator: @ethanbadger

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      RRID:AB_2783865 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2405471219303874
  27. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2783865

      DOI: 10.1016/j.molcel.2019.04.024

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      Curator: @ethanbadger

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      RRID:AB_2783865 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519303168