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TIGIT and PD-L1 co-blockade promotes dendritic cell-dependent production of non-exhausted CD8+ T cells

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.immuni.2026.10.005
  
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A stroma-sensing TGF-β blockade reprograms CAF-myeloid niches to induce durable tumor immunity

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.ccell.2026.10.007
  
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sciencedirect.com/science/article/pii/S1535610826004733
Aug 2026
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The SATvac model of CD8+ T cell expansion and contraction phases considering memory and effector cell differentiation

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1. scibot 27 Aug 2026
  
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  DOI: 10.1371/journal.pcbi.1014702
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13506100/
Jul 2026
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Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors

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1. scibot 06 Jul 2026
  
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2. scibot 05 Jul 2026
  
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sciencedirect.com/science/article/pii/S1074761326002578
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B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.003
  
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sciencedirect.com/science/article/pii/S1074761326002542
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LEF1 and niche factors determine T cell stemness across chronic diseases

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1. scibot 04 Jul 2026
  
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  DOI: 10.1016/j.cell.2026.06.022
  
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sciencedirect.com/science/article/pii/S0092867426007099
Jun 2026
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Stem-like precursors of exhausted Th cells upheld by a Tox-Myb-Eomes transcriptional hierarchy propagate Th cell responses in chronic infection

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1. scibot 26 Jun 2026
  
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sciencedirect.com/science/article/pii/S1074761326002311
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The transcription factor Eomes drives a stemness program in CD4+ T cells that promotes anti-tumor immunity in response to immunotherapy

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.018
  
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sciencedirect.com/science/article/pii/S1074761326002293
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Monocytic niches escape T cell surveillance and promote Mycobacterium tuberculosis persistence in lymph nodes

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.017
  
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sciencedirect.com/science/article/pii/S1074761326002281
May 2026
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Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.cell.2026.02.019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13235417/
Apr 2026
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Requirements for development of T helper 1 and T follicular helper cells from a common precursor

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117296
  
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sciencedirect.com/science/article/pii/S2211124726003748
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Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes

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1. scibot 23 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.022
  
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sciencedirect.com/science/article/pii/S1074761326001330
Feb 2026
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Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.006
  
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sciencedirect.com/science/article/pii/S1074761326000270
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Hormonal rewiring of immunity during dietary restriction ensures host defense and systemic glucose conservation

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.003
  
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sciencedirect.com/science/article/pii/S1074761326000026
Nov 2025
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.004
  
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sciencedirect.com/science/article/pii/S1074761325004340
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The transcription factor NFIL3 drives innate lymphoid cell specification from lymphoid progenitors

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1. scibot 01 Nov 2025
  
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  DOI: 10.1016/j.immuni.2025.10.005
  
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sciencedirect.com/science/article/pii/S1074761325004352
Aug 2025
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Enhanced formation of tertiary lymphoid structures shapes the anti-tumor microenvironment in hepatocellular carcinoma after FOLFOX-HAIC therapy

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102298
  
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sciencedirect.com/science/article/pii/S2666379125003714
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
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Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.005
  
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sciencedirect.com/science/article/pii/S1074761325002742
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
Feb 2025
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A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115301
  
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sciencedirect.com/science/article/pii/S2211124725000725
Jun 2024
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Therapeutic potential of co-signaling receptor modulation in hepatitis B

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.038
  
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May 2024
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101567
  
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Feb 2024
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Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.immuni.2023.12.006
  
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Dec 2023
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.018
  
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May 2023
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

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1. scibot 12 May 2023
  
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Apr 2023
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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

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  DOI: 10.1016/j.ccell.2023.03.015
  
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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1. scibot 05 Apr 2023
  
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  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Jan 2023
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CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.002
  
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Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors

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1. scibot 24 Jan 2023
  
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  DOI: 10.1016/j.medj.2022.12.007
  
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sciencedirect.com/science/article/pii/S2666634022005232
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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.ccell.2022.12.007
  
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sciencedirect.com/science/article/pii/S1535610822005931
Jun 2022
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Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.xpro.2022.101444
  
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sciencedirect.com/science/article/pii/S2666166722003240
Mar 2022
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

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1. scibot 18 Mar 2022
  
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  DOI: 10.1016/j.xcrm.2022.100554
  
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

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CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection

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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

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Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

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A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma

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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

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  DOI: 10.1016/j.cell.2021.07.015
  
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Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

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Feb 2021
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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

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  DOI: 10.3389/fimmu.2020.583382
  
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Nov 2020
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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

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Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19

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In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

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Jan 2020
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Untitled document

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  DOI: 10.1016/j.immuni.2019.04.010
  
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