70 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin
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    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.celrep.2024.114814

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      AB_2797703

      DOI: 10.1016/j.celrep.2024.114814

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    sciencedirect.com/science/article/pii/S2211124724011653
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
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    1. scibot 26 Sep 2024
      RRID:AB_2797703

      DOI: 10.1101/2024.09.03.611030

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    ncbi.nlm.nih.gov/pmc/articles/PMC11398411/
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    CircPOLA2 sensitizes non-small cell lung cancer cells to ferroptosis and suppresses tumorigenesis via the Merlin-YAP signaling pathway
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.isci.2024.110832

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    sciencedirect.com/science/article/pii/S2589004224020571
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    Heterogeneity of glial progenitor cells during the neurogenesis-to-gliogenesis switch in the developing human cerebral cortex
    1
    1. scibot 25 Sep 2024
      RRID:AB_2715512

      DOI: 10.1016/j.celrep.2021.108788

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    sciencedirect.com/science/article/pii/S2211124721001029
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    EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition
    1
    1. scibot 25 Sep 2024
      RRID:AB_2715512

      DOI: 10.1016/j.ccell.2019.12.015

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    sciencedirect.com/science/article/pii/S1535610819305859
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    OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
    1
    1. scibot 25 Sep 2024
      RRID:AB_2715512

      DOI: 10.1016/j.stem.2019.04.014

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    sciencedirect.com/science/article/pii/S1934590919301638
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.xcrm.2024.101703

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    sciencedirect.com/science/article/pii/S2666379124004245
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1016/j.isci.2021.103097

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    ncbi.nlm.nih.gov/pmc/articles/PMC8482499/
  12. www.mdpi.com www.mdpi.com
    Aspirin Inhibition of Group VI Phospholipase A2 Induces Synthetic Lethality in AAM Pathway Down-Regulated Gingivobuccal Squamous Carcinoma
    1
    1. scibot 02 Aug 2024
      9449

      DOI: 10.3390/cells11010123

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    mdpi.com/2073-4409/11/1/123/htm
  13. Jun 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109828

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    sciencedirect.com/science/article/pii/S2589004224010502
  15. May 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
    1
    1. scibot 30 May 2024
      RRID:AB_2797703

      DOI: 10.1016/j.ebiom.2024.105162

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    sciencedirect.com/science/article/pii/S235239642400197X
  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Repurposing AS1411 for constructing ANM-PROTACs
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.chembiol.2024.03.011

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    sciencedirect.com/science/article/pii/S2451945624001272
  19. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
      RRID:AB_2797703

      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  20. Mar 2024
  21. www.nature.com www.nature.com
    Monolayer culture alters EGFR inhibitor response through abrogation of microRNA-mediated feedback regulation
    1
    1. scibot 28 Mar 2024
      RRID:AB_2797703

      DOI: 10.1038/s41598-024-56920-7

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    nature.com/articles/s41598-024-56920-7
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
    1
    1. scibot 17 Nov 2023
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2023.113417

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    sciencedirect.com/science/article/pii/S2211124723014298
  24. Oct 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
    1
    1. scibot 12 Oct 2023
      RRID:AB_2797703

      DOI: 10.1158/2767-9764.CRC-23-0089

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  26. Aug 2023
  27. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      RRID:AB_2797703

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      RRID:AB_2797703

      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  28. Jul 2023
  29. www.sciencedirect.com www.sciencedirect.com
    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
    1
    1. scibot 27 Jul 2023
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2023.112833

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    sciencedirect.com/science/article/pii/S2211124723008446
  30. Jun 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
    1
    1. scibot 22 Jun 2023
      RRID:AB_2797703

      DOI: 10.1158/2767-9764.CRC-23-0030

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    ncbi.nlm.nih.gov/pmc/articles/PMC10281290/
  32. www.sciencedirect.com www.sciencedirect.com
    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
    1
    1. scibot 21 Jun 2023
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2023.112654

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    sciencedirect.com/science/article/pii/S2211124723006654
  33. May 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Modeling human ectopic pregnancies with trophoblast and vascular organoids
    1
    1. scibot 24 May 2023
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      DOI: 10.1016/j.celrep.2023.112546

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    sciencedirect.com/science/article/pii/S2211124723005570
  35. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
    1
    1. scibot 13 May 2023
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2023.112479

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    sciencedirect.com/science/article/pii/S2211124723004904
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    Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.ccell.2023.04.011

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    sciencedirect.com/science/article/pii/S153561082300137X
  37. Apr 2023
  38. www.sciencedirect.com www.sciencedirect.com
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
    1
    1. scibot 22 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112372

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    sciencedirect.com/science/article/pii/S2211124723003832
  39. Mar 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
    1
    1. scibot 16 Mar 2023
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2023.112252

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    sciencedirect.com/science/article/pii/S2211124723002632
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
    1
    1. scibot 05 Mar 2023
      RRID:AB_2797703

      DOI: 10.1158/0008-5472.CAN-21-2908

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444958/
  42. Feb 2023
  43. academic.oup.com academic.oup.com
    STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice
    1
    1. scibot 17 Feb 2023
      RRID:AB_2797703

      DOI: 10.1210/endocr/bqac215

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    academic.oup.com/endo/article/164/3/bqac215/6967061
  44. www.sciencedirect.com www.sciencedirect.com
    Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.xcrm.2023.100934

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    sciencedirect.com/science/article/pii/S2666379123000265
  45. Jan 2023
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis
    1
    1. scibot 31 Jan 2023
      AB_2797703

      DOI: 10.1002/hipo.23502

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    onlinelibrary.wiley.com/doi/10.1002/hipo.23502
  47. www.sciencedirect.com www.sciencedirect.com
    The human placenta shapes the phenotype of decidual macrophages
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111977

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    sciencedirect.com/science/article/pii/S2211124722018812
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anlotinib Suppressed Ovarian Cancer Progression via Inducing G2/M Phase Arrest and Apoptosis
    1
    1. scibot 11 Jan 2023
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      DOI: 10.3390/jcm12010162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9821756/
  49. Dec 2022
  50. www.sciencedirect.com www.sciencedirect.com
    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
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      DOI: 10.1016/j.celrep.2022.111819

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    sciencedirect.com/science/article/pii/S2211124722017119
  51. Nov 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
    1
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      DOI: 10.1016/j.ccell.2022.10.021

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    sciencedirect.com/science/article/pii/S1535610822005128
  53. Oct 2022
  54. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
    1
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      DOI: 10.1016/j.celrep.2022.111561

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    sciencedirect.com/science/article/pii/S221112472201422X
  55. www.sciencedirect.com www.sciencedirect.com
    Spatial epitope barcoding reveals clonal tumor patch behaviors
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      DOI: 10.1016/j.ccell.2022.09.014

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    sciencedirect.com/science/article/pii/S1535610822004433
  56. Sep 2022
  57. www.sciencedirect.com www.sciencedirect.com
    CDK14 inhibition reduces mammary stem cell activity and suppresses triple negative breast cancer progression
    1
    1. scibot 15 Sep 2022
      RRID:AB_2797703

      DOI: 10.1016/j.celrep.2022.111331

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    sciencedirect.com/science/article/pii/S2211124722011597
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
    1
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      DOI: 10.1016/j.isci.2022.104952

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    ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity
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      DOI: 10.1158/2159-8290.CD-21-0694

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  60. Aug 2022
  61. 52.53.155.43 52.53.155.43
    can-21-2908-html.html
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      DOI: 10.1158/0008-5472.can-21-2908

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  62. www.sciencedirect.com www.sciencedirect.com
    GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming
    1
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      AB_2797703

      DOI: 10.1016/j.jcmgh.2022.06.009

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    sciencedirect.com/science/article/pii/S2352345X22001552
  63. Jul 2022
  64. www.sciencedirect.com www.sciencedirect.com
    METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma
    1
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      CST, #9449

      DOI: 10.1016/j.ebiom.2022.104142

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  65. May 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
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    sciencedirect.com/science/article/pii/S1934590922001576
  67. Mar 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer
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      DOI: 10.1126/sciadv.abk3338

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  69. www.sciencedirect.com www.sciencedirect.com
    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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  70. www.sciencedirect.com www.sciencedirect.com
    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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  71. Feb 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration
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  73. Nov 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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  75. Oct 2021
  76. www.sciencedirect.com www.sciencedirect.com
    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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      DOI: 10.1158/0008-5472.CAN-21-1545

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  78. Aug 2021
  79. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
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  81. Jul 2021
  82. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lower androgen levels promote abnormal cartilage development in female patients with adolescent idiopathic scoliosis
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      DOI: 10.21037/atm-20-3171

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      DOI: 10.21037/atm-20-3171

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  84. May 2021
  85. peerj.com peerj.com
    Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells
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      DOI: 10.7717/peerj.11388

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  86. www.sciencedirect.com www.sciencedirect.com
    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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      DOI: 10.1016/j.devcel.2020.07.014

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    sciencedirect.com/science/article/pii/S1534580720305888
  87. Apr 2021
  88. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma
    1
    1. scibot 22 Apr 2021
      KI67

      DOI: 10.1016/j.ccell.2020.08.014

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    sciencedirect.com/science/article/pii/S1535610820304256
  89. Feb 2021
  90. www.nature.com www.nature.com
    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
    1
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      anti-Ki67

      DOI: 10.1038/s42255-020-00325-z

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    nature.com/articles/s42255-020-00325-z
  91. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14985

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14985
  92. Nov 2020
  93. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
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      anti-Ki67

      DOI: 10.1007/s10571-020-01006-x

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  94. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      DOI: 10.1002/1878-0261.12820

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12820
  95. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Lonidamine potentiates the oncolytic efficiency of M1 virus independent of hexokinase 2 but via inhibition of antiviral immunity
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      RRID:AB_2797703

      DOI: 10.1186/s12935-020-01598-w

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    cancerci.biomedcentral.com/article/10.1186/s12935-020-01598-w
  96. Oct 2020
  97. www.cell.com www.cell.com
    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
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      DOI: 10.1016/j.celrep.2020.108286

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    cell.com/cell-reports/abstract/S2211-1247(20)31275-4
  98. Sep 2020
  99. www.nature.com www.nature.com
    Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer
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      RRID:AB_2797703

      DOI: 10.1038/s41388-020-01416-7

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  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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      Ki-67

      DOI: 10.1016/j.celrep.2020.108092

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  101. Jan 2020
  102. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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      RRID:AB_2797703

      DOI: 10.1016/j.cmet.2019.06.014

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  103. www.sciencedirect.com www.sciencedirect.com
    Maturation of the Human Intestinal Immune System Occurs Early in Fetal Development
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      RRID:AB_2797703

      DOI: 10.1016/j.devcel.2019.09.008

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