16 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    EZH2 Inhibitors Sensitize Breast Cancer to HER2 Kinase Inhibitors through Cooperative Effects on YAP and Pro-apoptotic Regulators
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    aacrjournals.org/cancerres/article/86/6/1467/775076/EZH2-Inhibitors-Sensitize-Breast-Cancer-to-HER2
  3. May 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PROTAC-mediated degradation of TAF1 induces apoptosis in AML cells and inhibits tumor growth in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353786/
  5. Feb 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12883205/
  7. www.sciencedirect.com www.sciencedirect.com
    Proteomics landscape of early T-cell precursor acute lymphoblastic leukemia reveals deficient oxidative phosphorylation signatures
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    sciencedirect.com/science/article/pii/S2666379126000030
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856326/
  9. Sep 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402800/
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  13. Oct 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  15. Nov 2022
  16. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
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    aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
  17. Oct 2022
  18. 52.53.155.43 52.53.155.43
    ccr-22-1357-html.html
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    52.53.155.43/b06e31323fa05ae99a3ee4406ee4cfeac8533d8b/ccr-22-1357-html.html
  19. Apr 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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    sciencedirect.com/science/article/pii/S2211124722003709
  21. Oct 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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    sciencedirect.com/science/article/pii/S2211124721012791
  23. Aug 2021
  24. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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    sciencedirect.com/science/article/pii/S1535610821003834
  25. link.springer.com link.springer.com
    Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells
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    link.springer.com/article/10.1186/s13046-021-02057-8
  26. Jul 2021
  27. www.sciencedirect.com www.sciencedirect.com
    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
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    sciencedirect.com/science/article/pii/S1357272521001060
  28. Feb 2021
  29. www.sciencedirect.com www.sciencedirect.com
    Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site
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    sciencedirect.com/science/article/pii/S153561082030605X