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SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-xL in Clear Cell Renal Cell Carcinoma

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1. scibot 10 Jun 2026
  
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  RRID:AB_2798602
  
  DOI: 10.1158/0008-5472.CAN-25-3195
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13244386/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors

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1. scibot 25 Jul 2025
  
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  RRID:AB_2798602
  
  DOI: 10.7554/eLife.98372
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12286604/
www.biorxiv.org www.biorxiv.org

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance

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1. scibot 11 Jul 2025
  
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  RRID:AB_2798602
  
  DOI: 10.1101/2025.06.24.661170
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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biorxiv.org/content/10.1101/2025.06.24.661170v1
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia

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1. scibot 22 May 2025
  
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  RRID:AB_2798602
  
  DOI: 10.1038/s41598-025-01657-0
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12089620/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53

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1. scibot 11 Apr 2024
  
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  AB_2798602
  
  DOI: 10.21037/tlcr-24-160
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
Apr 2023
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Higher replication potential of West Nile virus governs apoptosis induction in human neuroblastoma cells

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1. scibot 27 Apr 2023
  
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  RRID:AB_2798602
  
  DOI: 10.1007/s10495-023-01844-2
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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link.springer.com/article/10.1007/s10495-023-01844-2
Feb 2023
www.sciencedirect.com www.sciencedirect.com

IFNγ signaling sensitizes melanoma cells to BH3 Mimetics

1
1. scibot 04 Feb 2023
  
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  RRID:AB_2798602
  
  DOI: 10.1016/j.jid.2023.01.017
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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sciencedirect.com/science/article/pii/S0022202X23000726
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Pituitary adenomas evade apoptosis via noxa deregulation in Cushing’s disease

1
1. scibot 26 Aug 2022
  
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  RRID:AB_2798602
  
  DOI: 10.1016/j.celrep.2022.111223
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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sciencedirect.com/science/article/pii/S2211124722010403
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

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1. scibot 13 Oct 2021
  
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  RRID:AB_2798602
  
  DOI: 10.1016/j.celrep.2021.109815
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
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sciencedirect.com/science/article/pii/S2211124721012791
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target

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1. scibot 01 Jul 2021
  
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  14766
  
  DOI: 10.1016/j.biocel.2021.106028
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:AB_2798602
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sciencedirect.com/science/article/pii/S1357272521001060
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

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1. scibot 22 Apr 2021
  
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  RRID:AB_2798602
  
  DOI: 10.1016/j.ccell.2020.10.010
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2798602
  
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  RRIDCUR:Validated RRID:AB_2798602
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1535610820305419
Jan 2020
www.sciencedirect.com www.sciencedirect.com

BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2798602
  
  DOI: 10.1016/j.ccell.2019.04.005
  
  Resource: (Cell Signaling Technology Cat# 14766, RRID:AB_2798602)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2798602
  
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  RRID:AB_2798602 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1535610819302004